Lonzo Ball has his most career points per game versus the Lakers, with 19.6 per game.

lonzo ball highest career ppg by opponent
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LALMILHOUSASPHXCHIGSWSACMINBKNDETOKCDALLACATLNYKUTABOSCHADENNOPTOR19.616.614.514.413.513.313.112.912.812.412.412.312.211.911.511.311.211.010.810.810.810.6
OPPGPPPGMPGRPGAPGSPGBPGTPGFGMFGAFG%3PM3PA3P%FTMFTAFT%MINPTSREBASTSTLBLKTOVPF+/-
LakersLakers
519.635.46.06.81.60.42.27.614.054.33.07.838.51.42.070.017798303482119+11
BucksBucks
516.634.07.07.61.81.03.06.013.444.84.08.646.50.61.442.917083353895158+5
RocketsRockets
1314.532.55.66.81.80.82.55.011.244.83.17.540.81.51.882.6423189738824113228+16
SpursSpurs
1114.435.05.47.41.70.42.55.312.143.63.07.142.30.81.460.038515859811942722+22
SunsSuns
1013.530.84.76.02.10.63.15.111.942.92.35.740.41.01.566.730813547602163125-12
BullsBulls
613.333.35.86.52.00.52.34.811.542.02.36.834.11.31.588.9200803539123147+26
WarriorsWarriors
1213.132.84.66.21.90.43.14.812.338.52.56.936.11.11.956.539315755742353724-48
KingsKings
912.931.95.08.21.70.72.05.011.443.72.26.335.10.71.350.028711645741561817+9
TimberwolvesTimberwolves
912.828.25.06.11.70.33.24.410.442.63.07.739.10.91.461.525411545551532918-21
NetsNets
912.431.15.14.41.10.41.64.911.642.32.26.037.00.41.140.028011246401041420-43
PistonsPistons
1012.434.56.45.91.60.92.65.010.746.72.04.940.80.40.757.134512464591692623+113
ThunderThunder
812.333.66.36.91.10.83.44.812.139.22.47.033.90.41.330.0268985055962731+9
MavericksMavericks
1312.232.15.95.21.20.21.54.511.339.53.07.539.80.30.933.341715977681632030-56
ClippersClippers
911.931.66.85.71.30.23.24.411.339.22.46.736.70.61.150.028410761511222921-50
HawksHawks
411.527.68.08.32.00.82.03.89.340.53.07.341.41.01.0100.011046323383810+19
KnicksKnicks
711.334.56.35.31.11.02.34.111.735.42.66.937.50.41.042.9242794437871623-26
JazzJazz
1111.232.25.05.61.20.52.34.512.635.31.75.332.80.51.054.535412355621362530-2
CelticsCeltics
511.035.87.27.81.01.23.64.011.634.52.46.636.40.60.875.017955363956189-15
HornetsHornets
610.831.34.26.81.50.71.84.29.046.32.56.240.50.00.30.0188652541941112+1
NuggetsNuggets
1210.835.07.86.81.81.02.64.411.139.81.85.831.40.20.440.0420130948121123119+52
PelicansPelicans
410.835.58.88.81.30.82.54.012.332.71.57.819.41.31.583.314243353553109+5
RaptorsRaptors
710.629.25.34.01.30.72.93.69.039.72.65.745.00.91.175.0204743728952011-4
Trail BlazersTrail Blazers
1310.531.34.36.11.30.62.33.99.939.52.25.540.80.40.571.440713656791783034-4
GrizzliesGrizzlies
1010.432.25.35.71.70.52.13.910.138.61.96.131.10.71.353.832210453571752121+85
PacersPacers
710.334.15.64.70.40.63.13.99.142.22.15.638.50.40.950.0238723933342216-7
CavaliersCavaliers
89.834.86.18.01.90.62.93.610.335.41.86.029.20.81.166.72787849641552315+29
HeatHeat
99.734.26.45.61.80.72.93.711.133.02.06.929.00.30.937.53078758501662616+3
76ers76ers
69.531.45.34.31.80.82.53.710.734.41.76.027.80.51.050.01885732261151515-22
WizardsWizards
78.429.25.65.71.71.31.93.010.030.01.76.725.50.71.450.0204593940129139-29
MagicMagic
78.029.95.96.01.90.72.62.98.633.32.05.934.10.30.740.02095641421351815+6