Wilt Chamberlain had the most games with 48+ points, with 138 games.

Interpreted as:

most 48 or more point regular-season games by a player in NBA history

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	Wilt Chamberlain W. Chamberlain	138	7,742		56.1	26.1				22.8	41.2	55.4				10.4	17.4	59.9	57.4					3,600					247
2	Michael Jordan M. Jordan	44	2,311	42.5	52.5	7.7	4.5	3.1	1.3	19.6	33.0	59.3	1.0	2.4	43.3	12.4	14.2	87.2	67.0	2.3	5.4	2.9	1,871	337	200	135	57	129	133	+55
3	James Harden J. Harden	30	1,604	39.8	53.5	7.4	7.8	2.1	0.7	15.8	29.8	53.1	6.6	14.4	45.8	15.3	17.0	89.6	71.7	1.4	6.0	5.1	1,195	222	234	64	20	152	93	+389
4	Kobe Bryant K. Bryant	30	1,618	43.4	53.9	6.3	3.3	1.6	0.4	18.6	34.7	53.5	4.1	9.0	45.7	12.7	14.3	88.8	65.7	1.0	5.3	2.8	1,302	188	99	48	13	84	79	+331
5	Elgin Baylor E. Baylor	24	1,270		52.9					19.5						13.9	17.4	80.1											90
6	Stephen Curry S. Curry	20	1,045	36.4	52.3	5.3	5.1	1.6	0.4	16.9	28.0	60.4	9.9	16.8	58.8	8.6	9.1	95.0	81.7	0.5	4.8	3.1	729	105	102	31	8	62	39	+208
7	Rick Barry R. Barry	20	1,034	44.3	51.7	8.5	5.1	3.3		20.1	38.8	51.8				11.5	12.9	89.5	58.1	1.0	6.3	2.0	886	169	101	23		4	65
8	Damian Lillard D. Lillard	17	923	39.2	54.3	4.5	7.4	1.4	0.2	16.8	28.9	58.1	7.8	14.2	54.8	12.9	13.6	94.4	77.7	0.5	4.0	2.4	667	76	126	23	4	40	24	+191
9	LeBron James L. James	16	840	42.1	52.5	8.0	7.1	1.4	0.9	18.0	29.9	60.3	5.1	9.1	56.2	11.4	13.9	81.6	72.9	1.5	6.5	3.0	674	128	114	23	14	48	35	+161
10	Allen Iverson A. Iverson	14	727	45.3	51.9	4.5	5.6	2.6	0.1	18.4	33.2	55.3	2.8	5.9	47.6	12.4	15.1	82.1	65.1	0.9	3.6	4.6	634	63	79	36	2	64	36	+83
11	Kareem Abdul-Jabbar K. Abdul-Jabbar	14	714		51.0	14.3	4.5	0.3	2.3	20.2	31.8	63.6				10.6	14.1	74.7	67.1					200	63	1	7
12	Giannis Antetokounmpo G. Antetokounmpo	13	681	37.0	52.4	13.2	4.8	1.5	0.8	18.8	29.5	64.0	1.7	4.7	36.1	13.0	17.0	76.5	70.9	2.8	10.3	2.8	481	171	63	19	11	37	33	+144
13	Devin Booker D. Booker	12	648	39.1	54.0	5.3	6.7	1.2	0.5	19.0	31.3	60.6	4.7	9.9	47.1	11.3	12.7	89.5	73.2	0.8	4.5	3.1	469	64	80	14	6	37	33	+60
14	Kevin Durant K. Durant	12	613	43.8	51.1	7.6	5.9	1.8	0.9	16.8	31.0	54.0	5.0	10.2	49.2	12.6	14.0	89.9	68.7	0.7	6.9	3.8	526	91	71	21	11	45	29	+56
15	Dominique Wilkins D. Wilkins	12	616	42.3	51.3	7.5	2.8	2.3	0.6	18.0	31.3	57.6	1.3	2.5	50.0	14.1	16.3	86.2	66.8	3.0	4.5	3.5	507	90	33	28	7	42	28
16	Bob Pettit B. Pettit	12	605		50.4					19.0	34.5	55.1				12.4	15.2	81.9	61.2										44
17	Joel Embiid J. Embiid	11	580	35.0	52.7	13.0	4.5	1.4	2.3	18.5	28.2	65.8	0.8	2.7	30.0	14.8	16.3	91.1	74.6	3.6	9.4	2.8	385	143	49	15	25	31	33	+164
18	Luka Dončić L. Dončić	10	535	40.0	53.5	10.4	8.5	1.7	0.7	17.7	28.1	63.0	6.3	12.2	51.6	11.8	15.0	78.7	77.1	1.0	9.4	3.8	400	104	85	17	7	38	28	+108
19	Russell Westbrook R. Westbrook	10	512	40.6	51.2	11.4	9.1	2.3	0.3	17.5	35.9	48.7	3.7	10.2	36.3	12.5	14.9	83.9	60.3	2.3	9.1	4.2	406	114	91	23	3	42	32	+34
20	Larry Bird L. Bird	10	504	42.5	50.4	11.2	6.2	1.6	0.7	19.0	30.8	61.7	1.3	4.0	32.5	11.1	11.7	94.9	70.1	2.2	9.0	3.6	425	112	62	16	7	36	25
21	Kyrie Irving K. Irving	9	471	39.2	52.3	5.4	4.9	2.1	0.4	17.3	28.4	60.9	7.6	12.2	61.8	10.1	11.1	91.0	78.5	1.1	4.3	1.8	353	49	44	19	4	16	25	+162
22	Bernard King B. King	9	468	42.1	52.0	8.1	3.7	1.1	0.2	19.4	30.9	62.9	0.0	0.3	0.0	13.1	15.9	82.5	68.6	3.2	4.9	3.3	379	73	33	10	2	30	29
23	Bob McAdoo B. McAdoo	9	449		49.9	17.4	2.8			20.3	29.8	68.3				9.2	12.0	76.9	71.2					157	25				31
24	Oscar Robertson O. Robertson	9	443		49.2	10.9	8.8			16.6	30.3	54.6				16.1	18.1	89.0	64.3					98	79				25
25	Tracy McGrady T. McGrady	8	408	42.8	51.0	8.8	5.0	2.3	1.3	18.3	33.0	55.3	5.4	10.4	51.8	9.1	13.5	67.6	65.5	2.6	6.1	3.8	342	70	40	18	10	30	19	+57