Wilt Chamberlain had the most games with 50+ points, with 118 games.

Interpreted as:

most efficient 50 or more point regular-season games by a player NBA

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	Wilt Chamberlain W. Chamberlain	118	6,772		57.4	26.3				23.5	41.9	56.0				10.4	17.5	59.5	57.8					3,102					209
2	Michael Jordan M. Jordan	31	1,677	42.4	54.1	7.6	4.5	3.4	1.2	20.0	32.8	60.9	1.2	2.5	47.4	13.0	14.7	88.4	68.9	2.0	5.6	2.9	1,313	236	140	104	37	89	93	+40
3	James Harden J. Harden	25	1,362	40.0	54.5	7.6	8.2	2.1	0.6	16.1	30.0	53.5	6.8	14.6	46.4	15.6	17.3	90.0	72.4	1.4	6.1	5.3	999	189	204	52	15	133	76	+330
4	Kobe Bryant K. Bryant	25	1,377	44.0	55.1	6.3	3.4	1.6	0.5	18.7	35.0	53.4	4.3	9.4	45.5	13.4	15.1	89.1	66.2	1.0	5.3	2.7	1,101	158	86	39	12	68	67	+285
5	Elgin Baylor E. Baylor	17	930		54.7	18.6				20.5						13.8	17.6	78.0						317					64
6	Damian Lillard D. Lillard	15	826	39.4	55.1	4.4	7.4	1.4	0.2	17.0	29.4	57.8	7.7	14.5	53.5	13.3	14.1	94.3	77.3	0.5	3.9	2.4	590	66	111	21	3	36	22	+165
7	Stephen Curry S. Curry	15	801	36.9	53.4	5.5	5.5	1.7	0.4	17.4	28.3	61.6	9.9	16.5	59.7	8.7	9.2	94.9	82.6	0.4	5.1	3.4	553	83	83	25	6	51	26	+142
8	LeBron James L. James	14	744	42.5	53.1	7.9	7.1	1.5	0.9	18.4	30.6	59.9	5.2	9.3	56.2	11.2	13.9	80.5	72.3	1.4	6.4	3.2	595	110	99	21	12	45	31	+135
9	Rick Barry R. Barry	14	743	44.3	53.1	8.8	6.1	3.5		20.9	38.3	54.5				11.4	12.6	90.3	60.6	1.0	6.3	2.0	620	123	86	21		4	42
10	Allen Iverson A. Iverson	11	582	45.3	52.9	4.4	5.5	2.5	0.2	18.6	33.8	55.1	2.7	5.5	49.2	12.9	16.0	80.7	64.7	0.9	3.5	4.5	499	48	61	28	2	50	30	+69
11	Kareem Abdul-Jabbar K. Abdul-Jabbar	10	521		52.1	12.7	5.4	0.5	2.5	20.3	31.7	64.0				11.5	15.1	76.2	67.9					127	54	1	5
12	Giannis Antetokounmpo G. Antetokounmpo	9	488	36.8	54.2	14.0	4.8	1.3	0.6	18.9	29.2	64.6	1.6	4.4	35.0	14.9	18.7	79.8	72.4	3.1	10.9	3.3	331	126	43	12	5	30	21	+126
13	Kevin Durant K. Durant	9	468	44.2	52.0	7.9	5.6	1.4	0.7	17.2	30.3	56.8	5.4	10.0	54.4	12.1	13.7	88.6	71.5	0.9	7.0	4.2	398	71	50	13	6	38	21	+55
14	Joel Embiid J. Embiid	8	435	35.3	54.4	13.5	4.9	1.0	2.5	19.1	28.6	66.8	0.9	2.5	35.0	15.3	17.0	89.7	75.3	3.8	9.8	2.9	283	108	39	8	20	23	22	+122
15	Devin Booker D. Booker	8	454	38.9	56.8	5.5	5.4	0.9	0.6	19.9	32.3	61.6	5.5	10.8	51.2	11.5	13.0	88.5	74.7	1.0	4.5	3.5	311	44	43	7	5	28	22	+44
16	Bernard King B. King	8	419	42.0	52.4	7.8	3.5	1.1	0.3	19.4	30.4	63.8	0.0	0.4	0.0	13.6	16.6	82.0	69.5	3.3	4.5	3.4	336	62	28	9	2	27	26
17	Luka Dončić L. Dončić	7	388	41.5	55.4	9.7	8.9	2.4	0.9	18.6	28.3	65.7	6.0	11.7	51.2	12.3	15.6	78.9	78.9	1.0	8.7	4.3	291	68	62	17	6	30	20	+60
18	Dominique Wilkins D. Wilkins	7	374	42.3	53.4	5.9	2.4	2.3	0.9	19.0	31.4	60.5	0.9	1.7	50.0	14.6	17.4	83.6	68.3	2.4	3.4	3.4	296	41	17	16	6	24	16
19	Kyrie Irving K. Irving	6	326	37.9	54.3	4.8	5.3	2.0	0.5	18.0	29.0	62.1	8.2	12.2	67.1	10.2	11.0	92.4	80.3	1.2	3.7	2.2	228	29	32	12	3	13	17	+106
20	Adrian Dantley A. Dantley	6	316	43.5	52.7	7.7	4.2	1.2	0.2	19.3	26.7	72.5	0.0	0.0		14.0	16.3	85.7	77.8			2.7	261	46	25	7	1	16	21
21	Pete Maravich P. Maravich	6	320	46.2	53.3	4.8	4.3			21.0	35.0	60.0				11.3	13.5	84.0	65.1				277	29	26				20
22	Bob Pettit B. Pettit	6	313		52.2					20.5	34.0	60.3				11.2	14.2	78.8	64.8										18
23	Shai Gilgeous-Alexander S. Gilgeous-Alexander	5	262	38.4	52.4	6.4	5.2	1.8	1.0	16.8	30.8	54.5	3.0	7.8	38.5	15.8	17.4	90.8	68.1	1.4	5.0	2.2	192	32	26	9	5	11	15	+67
24	Jayson Tatum J. Tatum	5	269	40.1	53.8	8.4	4.8	0.0	0.4	17.0	28.6	59.4	7.0	11.6	60.3	12.8	14.0	91.4	77.4	1.6	6.8	2.4	201	42	24	0	2	12	13	+69
25	Bradley Beal B. Beal	5	269	40.2	53.8	4.4	3.0	0.8	0.6	18.8	32.6	57.7	5.6	10.6	52.8	10.6	12.2	86.9	70.8	2.4	2.0	4.6	201	22	15	4	3	23	15	+3