Wilt Chamberlain has scored the most points in a loss, with 78 points against the Lakers on December 8, 1961.

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All-time
Regular season

	NAME	PTS	DATE	TM		OPP	MIN	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Wilt Chamberlain W. Chamberlain	78	12/8/1961	PHI	vs	LAL	63	43	1			31	62	50.0				16	31	51.6	51.6				4
2	David Thompson D. Thompson	73	4/9/1978	DEN	@	DET	43	7	2	0	1	28	38	73.7				17	20	85.0	78.0	3	4	4	2
3	Wilt Chamberlain W. Chamberlain	72	11/3/1962	SFW	@	LAL	48	18	1			29	48	60.4				14	18	77.8	64.4				0
4	Devin Booker D. Booker	70	3/24/2017	PHX	@	BOS	45	8	6	3	1	21	40	52.5	4	11	36.4	24	26	92.3	68.0	2	6	5	3	-6
5	Wilt Chamberlain W. Chamberlain	70	3/10/1963	SFW	@	SYR	48	18	3			27	38	71.1				16	22	72.7	73.4				2
6	Wilt Chamberlain W. Chamberlain	67	1/11/1963	SFW	vs	LAL	48	25	1			28	47	59.6				11	17	64.7	61.5				1
7	Wilt Chamberlain W. Chamberlain	67	2/25/1962	PHI	vs	NYK	48	21	1			25	38	65.8				17	22	77.3	70.3				1
8	Wilt Chamberlain W. Chamberlain	67	2/17/1962	PHI	@	STL	48	28	2			26	44	59.1				15	20	75.0	63.4				1
9	Wilt Chamberlain W. Chamberlain	65	2/13/1962	PHI	@	CIN	48	22	4			24	40	60.0				17	30	56.7	61.1				3
10	Michael Jordan M. Jordan	64	1/16/1993	CHI	vs	ORL	47	6	1	5	0	27	49	55.1	1	5	20.0	9	11	81.8	59.4	4	2	2	5
11	George Gervin G. Gervin	63	4/9/1978	SAS	@	NOJ	33	2	1	2	1	23	49	46.9				17	20	85.0	54.5				3
12	Wilt Chamberlain W. Chamberlain	63	11/26/1964	SFW	@	PHI	48	32	3			27	58	46.6				9	20	45.0	47.2				2
13	Wilt Chamberlain W. Chamberlain	63	12/14/1962	SFW	vs	LAL	48	30	1			24	41	58.5				15	20	75.0	63.3				4
14	Devin Booker D. Booker	62	1/26/2024	PHX	@	IND	38	5	4	1	2	22	37	59.5	6	12	50.0	12	13	92.3	72.6	0	5	4	2	+1
15	Karl-Anthony Towns K. Towns	62	1/22/2024	MIN	vs	CHA	38	8	2	0	0	21	35	60.0	10	15	66.7	10	14	71.4	75.3	3	5	7	2	0
16	Wilt Chamberlain W. Chamberlain	62	1/14/1962	PHI	@	BOS	48	28	2			27	45	60.0				8	11	72.7	62.2				1
17	Nikola Jokić N. Jokić	61	4/1/2025	DEN	vs	MIN	53	10	10	2	0	18	29	62.1	6	11	54.5	19	24	79.2	77.1	2	8	4	5	+2
18	Jalen Brunson J. Brunson	61	3/29/2024	NYK	@	SAS	43	4	6	1	0	25	47	53.2	5	13	38.5	6	6	100.0	61.4	1	3	1	2	+20
19	Michael Jordan M. Jordan	61	4/16/1987	CHI	vs	ATL	41	10	1	4	1	22	38	57.9	0	3	0.0	17	21	81.0	64.6	5	5	3	3
20	Wilt Chamberlain W. Chamberlain	61	11/21/1962	SFW	vs	CIN	48	22	3			27	52	51.9				7	15	46.7	52.0				3
21	De'Aaron Fox D. Fox	60	11/15/2024	SAC	vs	MIN	44	3	7	3	1	22	35	62.9	6	10	60.0	10	11	90.9	75.3	2	1	6	3	+1
22	Stephen Curry S. Curry	60	2/3/2024	GSW	@	ATL	41	6	4	0	1	22	38	57.9	10	23	43.5	6	6	100.0	73.8	1	5	2	1	-1
23	Bradley Beal B. Beal	60	1/6/2021	WAS	@	PHI	38	7	5	1	0	20	35	57.1	7	10	70.0	13	15	86.7	72.1	4	3	4	3	-9
24	Damian Lillard D. Lillard	60	11/8/2019	POR	vs	BKN	40	4	5	0	0	19	33	57.6	7	16	43.8	15	15	100.0	75.8	0	4	2	1	+4
25	Kemba Walker K. Walker	60	11/17/2018	CHA	vs	PHI	45	7	4	4	0	21	34	61.8	6	14	42.9	12	12	100.0	76.4	0	7	9	2	+1