The San Francisco 49ers had a record of 4-1 at home against the Patriots between the 1971 and 2013 seasons.
| OPP | REC | W% | GP | W | L | T | TD | PTS | PPG | OPP PTS | OPP PPG | 1DWN | 3DWN% | 4DWN% | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 4-1 | .800 | 5 | 4 | 1 | 0 | 18 | 134 | 26.8 | 80 | 16.0 | 89 | |||
| 2 | 4-1 | .800 | 5 | 4 | 1 | 0 | 15 | 114 | 22.8 | 63 | 12.6 | 113 | |||
| 3 | 3-2 | .600 | 5 | 3 | 2 | 0 | 17 | 141 | 28.2 | 116 | 23.2 | 105 | 0.0 | ||
| 4 | 3-2 | .600 | 5 | 3 | 2 | 0 | 13 | 103 | 20.6 | 121 | 24.2 | 97 | |||
| 5 | 3-4 | .429 | 7 | 3 | 4 | 0 | 13 | 121 | 17.3 | 132 | 18.9 | 122 | |||
| 6 | 5-1 | .833 | 6 | 5 | 1 | 0 | 15 | 123 | 20.5 | 92 | 15.3 | 112 | |||
| 7 | 3-4 | .429 | 7 | 3 | 4 | 0 | 21 | 167 | 23.9 | 144 | 20.6 | 140 | |||
| 8 | 3-3 | .500 | 6 | 3 | 3 | 0 | 15 | 126 | 21.0 | 119 | 19.8 | 128 | |||
| 9 | 4-1 | .800 | 5 | 4 | 1 | 0 | 14 | 114 | 22.8 | 87 | 17.4 | 111 | |||
| 10 | 3-3 | .500 | 6 | 3 | 3 | 0 | 16 | 124 | 20.7 | 79 | 13.2 | 110 | 75.0 | ||
| 11 | 1-1 | .500 | 2 | 1 | 1 | 0 | 5 | 43 | 21.5 | 41 | 20.5 | 50 | |||
| 12 | 3-3 | .500 | 6 | 3 | 3 | 0 | 20 | 155 | 25.8 | 130 | 21.7 | 116 | |||
| 13 | 4-3 | .571 | 7 | 4 | 3 | 0 | 24 | 179 | 25.6 | 123 | 17.6 | 148 | |||
| 14 | 3-2 | .600 | 5 | 3 | 2 | 0 | 9 | 102 | 20.4 | 79 | 15.8 | 98 | |||
| 15 | 1-1 | .500 | 2 | 1 | 1 | 0 | 6 | 45 | 22.5 | 29 | 14.5 | 28 | 33.3 | 100.0 | |
| 16 | 2-0 | 1.000 | 2 | 2 | 0 | 0 | 6 | 54 | 27.0 | 20 | 10.0 | 36 | 36.7 | 0.0 | |
| 17 | 1-0 | 1.000 | 1 | 1 | 0 | 0 | 2 | 20 | 20.0 | 3 | 3.0 | 15 | 50.0 | 100.0 |
JetsMore 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
