Between the 2000 and 2013 seasons, the San Francisco 49ers had their most points in a home game against the Cardinals on December 7, 2003, with 50 points.
Interpreted as:
49ers most points in a home regular-season game from 2000 to 2013| TEAM | PTS | DATE | TM | OPP | RESULT | PASS TD | RUSH TD | RET TD | TD | FGM | XPM | XP2 | SFTY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 50 | 12/7/2003 | vs | W 50-14 | 4 | 3 | 0 | 7 | 0 | 6 | 0 | 1 | ||
| 2 | | 49ers | 49 | 9/7/2003 | vs | W 49-7 | 2 | 2 | 1 | 5 | 5 | 4 | 0 | 0 | ||
| 3 | | 49ers | 48 | 10/9/2011 | vs | W 48-3 | 3 | 2 | 1 | 6 | 2 | 6 | 0 | 0 | ||
| 4 | | 49ers | 45 | 10/7/2012 | vs | W 45-3 | 3 | 3 | 0 | 6 | 1 | 6 | 0 | 0 | ||
| 5 | | 49ers | 40 | 12/12/2010 | vs | W 40-21 | 3 | 0 | 1 | 4 | 4 | 4 | 0 | 0 | ||
| 6 | | 49ers | 38 | 1/2/2011 | vs | W 38-7 | 2 | 2 | 1 | 5 | 1 | 5 | 0 | 0 | ||
| 7 | | 49ers | 38 | 10/27/2002 | vs | W 38-28 | 4 | 1 | 0 | 5 | 1 | 5 | 0 | 0 | ||
| 8 | | 49ers | 37 | 10/6/2002 | vs | W 37-13 | 1 | 2 | 1 | 4 | 3 | 4 | 0 | 0 | ||
| 9 | | 49ers | 35 | 10/4/2009 | vs | W 35-0 | 2 | 0 | 3 | 5 | 0 | 5 | 0 | 0 | ||
| 10 | | 49ers | 35 | 11/16/2008 | vs | W 35-16 | 2 | 3 | 0 | 5 | 0 | 5 | 0 | 0 | ||
| 11 | | 49ers | 35 | 12/2/2001 | vs | W 35-0 | 2 | 3 | 0 | 5 | 0 | 5 | 0 | 0 | ||
| 12 | | 49ers | 34 | 12/23/2013 | vs | W 34-24 | 1 | 2 | 1 | 4 | 2 | 4 | 0 | 0 | ||
| 13 | | 49ers | 34 | 10/6/2013 | vs | W 34-3 | 1 | 2 | 1 | 4 | 2 | 4 | 0 | 0 | ||
| 14 | | 49ers | 34 | 9/8/2013 | vs | W 34-28 | 3 | 1 | 0 | 4 | 2 | 4 | 0 | 0 | ||
| 15 | | 49ers | 34 | 10/8/2006 | vs | W 34-20 | 3 | 0 | 1 | 4 | 2 | 4 | 0 | 0 | ||
| 16 | | 49ers | 33 | 9/11/2011 | vs | W 33-17 | 0 | 1 | 2 | 3 | 4 | 3 | 0 | 0 | ||
| 17 | | 49ers | 32 | 10/13/2013 | vs | W 32-20 | 2 | 1 | 0 | 3 | 3 | 3 | 0 | 1 | ||
| 18 | | 49ers | 32 | 11/19/2012 | vs | W 32-7 | 2 | 1 | 0 | 3 | 3 | 3 | 0 | 1 | ||
| 19 | | 49ers | 31 | 9/21/2008 | vs | W 31-13 | 2 | 2 | 0 | 4 | 1 | 4 | 0 | 0 | ||
| 20 | | 49ers | 31 | 9/25/2005 | vs | L 31-34 | 3 | 0 | 1 | 4 | 1 | 4 | 0 | 0 | ||
| 21 | | 49ers | 31 | 10/10/2004 | vs | W 31-28 | 2 | 0 | 1 | 3 | 3 | 0 | 2 | 0 | ||
| 22 | | 49ers | 31 | 12/1/2002 | vs | W 31-24 | 0 | 3 | 1 | 4 | 1 | 4 | 0 | 0 | ||
| 23 | | 49ers | 30 | 11/17/2003 | vs | W 30-14 | 2 | 1 | 0 | 3 | 3 | 3 | 0 | 0 | ||
| 24 | | 49ers | 30 | 11/2/2003 | vs | W 30-10 | 3 | 0 | 1 | 4 | 1 | 3 | 0 | 0 | ||
| 25 | | 49ers | 28 | 9/11/2005 | vs | W 28-25 | 2 | 1 | 1 | 4 | 0 | 4 | 0 | 0 | ||
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Team Leaders 
PASS
2,151
Jones
RUSH
922
McCaffrey
REC
820
McCaffrey
Team Rankings
PPG
24.6
11th
OPP PPG
20.9
11th
RUSH YDS/G
101.4
25th
PASS YDS/G
256.6
6th
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| AFC East | W | L | T | PCT |
|---|---|---|---|---|
11 | 3 | 0 | .786 | |
10 | 4 | 0 | .714 | |
 Dolphins - e | 6 | 8 | 0 | .429 |
 Jets - e | 3 | 11 | 0 | .214 |
| AFC North | W | L | T | PCT |
8 | 6 | 0 | .571 | |
7 | 7 | 0 | .500 | |
 Bengals - e | 4 | 10 | 0 | .286 |
 Browns - e | 3 | 11 | 0 | .214 |
| AFC South | W | L | T | PCT |
10 | 4 | 0 | .714 | |
9 | 5 | 0 | .643 | |
8 | 6 | 0 | .571 | |
 Titans - e | 2 | 12 | 0 | .143 |
| AFC West | W | L | T | PCT |
 Broncos - x | 12 | 2 | 0 | .857 |
10 | 4 | 0 | .714 | |
 Chiefs - e | 6 | 8 | 0 | .429 |
 Raiders - e | 2 | 12 | 0 | .143 |
Patriots
Ravens
Jaguars
Chargers| NFC East | W | L | T | PCT |
|---|---|---|---|---|
9 | 5 | 0 | .643 | |
6 | 7 | 1 | .464 | |
 Commanders - e | 4 | 10 | 0 | .286 |
 Giants - e | 2 | 12 | 0 | .143 |
| NFC North | W | L | T | PCT |
10 | 4 | 0 | .714 | |
9 | 4 | 1 | .679 | |
8 | 6 | 0 | .571 | |
 Vikings - e | 6 | 8 | 0 | .429 |
| NFC South | W | L | T | PCT |
7 | 7 | 0 | .500 | |
7 | 7 | 0 | .500 | |
 Falcons - e | 5 | 9 | 0 | .357 |
 Saints - e | 4 | 10 | 0 | .286 |
| NFC West | W | L | T | PCT |
 Rams - x | 11 | 3 | 0 | .786 |
11 | 3 | 0 | .786 | |
10 | 4 | 0 | .714 | |
 Cardinals - e | 3 | 11 | 0 | .214 |
Eagles
Panthers
