The San Francisco 49ers have a 29-28 record against the NFC West in the regular-season and playoffs since 2017.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 9/17/2017 | 0-1 | @ | L 9-12 | .000 | 0 | 11 | 248 | 312 | 16.7 | |||
| 2 | | 49ers | 9/21/2017 | 0-1 | vs | L 39-41 | .000 | 5 | 25 | 421 | 418 | 50.0 | 66.7 | ||
| 3 | | 49ers | 10/1/2017 | 0-1 | @ | L 15-18 | .000 | 0 | 20 | 305 | 368 | 26.3 | 100.0 | ||
| 4 | | 49ers | 11/5/2017 | 0-1 | vs | L 10-20 | .000 | 1 | 17 | 329 | 368 | 35.3 | 0.0 | ||
| 5 | | 49ers | 11/26/2017 | 0-1 | vs | L 13-24 | .000 | 1 | 16 | 280 | 318 | 31.3 | 100.0 | ||
| 6 | | 49ers | 12/31/2017 | 1-0 | @ | W 34-13 | 1.000 | 4 | 25 | 461 | 251 | 50.0 | |||
| 7 | | 49ers | 10/7/2018 | 0-1 | vs | L 18-28 | .000 | 3 | 33 | 447 | 220 | 58.8 | 50.0 | ||
| 8 | | 49ers | 10/21/2018 | 0-1 | vs | L 10-39 | .000 | 1 | 16 | 228 | 339 | 27.3 | 0.0 | ||
| 9 | | 49ers | 10/28/2018 | 0-1 | @ | L 15-18 | .000 | 1 | 16 | 267 | 321 | 35.7 | |||
| 10 | | 49ers | 12/2/2018 | 0-1 | @ | L 16-43 | .000 | 2 | 24 | 452 | 331 | 43.8 | 50.0 | ||
| 11 | | 49ers | 12/16/2018 | 1-0 | vs | W 26-23 | 1.000 | 2 | 20 | 351 | 385 | 30.0 | |||
| 12 | | 49ers | 12/30/2018 | 0-1 | @ | L 32-48 | .000 | 4 | 22 | 391 | 377 | 27.3 | 100.0 | ||
| 13 | | 49ers | 10/13/2019 | 1-0 | @ | W 20-7 | 1.000 | 2 | 22 | 331 | 157 | 47.1 | 100.0 | ||
| 14 | | 49ers | 10/31/2019 | 1-0 | @ | W 28-25 | 1.000 | 4 | 21 | 411 | 357 | 64.7 | 100.0 | ||
| 15 | | 49ers | 11/11/2019 | 0-1 | vs | L 24-27 | .000 | 2 | 21 | 302 | 336 | 40.0 | 0.0 | ||
| 16 | | 49ers | 11/17/2019 | 1-0 | vs | W 36-26 | 1.000 | 5 | 26 | 442 | 266 | 46.2 | 0.0 | ||
| 17 | | 49ers | 12/21/2019 | 1-0 | vs | W 34-31 | 1.000 | 4 | 19 | 334 | 395 | 40.0 | |||
| 18 | | 49ers | 12/29/2019 | 1-0 | @ | W 26-21 | 1.000 | 3 | 18 | 398 | 348 | 50.0 | |||
| 19 | | 49ers | 9/13/2020 | 0-1 | vs | L 20-24 | .000 | 2 | 18 | 366 | 404 | 18.2 | 0.0 | ||
| 20 | | 49ers | 10/18/2020 | 1-0 | vs | W 24-16 | 1.000 | 3 | 24 | 390 | 311 | 38.5 | 100.0 | ||
| 21 | | 49ers | 11/1/2020 | 0-1 | @ | L 27-37 | .000 | 4 | 24 | 351 | 350 | 46.2 | 100.0 | ||
| 22 | | 49ers | 11/29/2020 | 1-0 | @ | W 23-20 | 1.000 | 2 | 18 | 345 | 308 | 21.4 | 100.0 | ||
| 23 | | 49ers | 12/26/2020 | 1-0 | @ | W 20-12 | 1.000 | 3 | 22 | 398 | 350 | 22.2 | |||
| 24 | | 49ers | 1/3/2021 | 0-1 | vs | L 23-26 | .000 | 2 | 17 | 328 | 280 | 40.0 | 100.0 | ||
| 25 | | 49ers | 10/3/2021 | 0-1 | vs | L 21-28 | .000 | 3 | 23 | 457 | 234 | 14.3 | 75.0 | ||
| Average | .509 | 2.8 | 20.7 | 361.2 | 323.6 | 41.0 | 0.0 | ||||||||
| Total | 29-28 | .509 | 158 | 1,181 | 20,586 | 18,444 | 41.0 | 51.6 | |||||||
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More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |