The San Francisco 49ers are 6-4 against the Cardinals between September 25, 2021 and September 25, 2026.
| TEAM | DATE | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 10/10/2021 | @ | L 10-17 | 1 | 19 | 338 | 304 | 27.3 | 20.0 | ||
| 2 | | 49ers | 11/7/2021 | vs | L 17-31 | 2 | 22 | 337 | 437 | 40.0 | |||
| 3 | | 49ers | 11/21/2022 | @ | W 38-10 | 5 | 21 | 387 | 314 | 54.5 | |||
| 4 | | 49ers | 1/8/2023 | vs | W 38-13 | 5 | 21 | 311 | 255 | 46.2 | 0.0 | ||
| 5 | | 49ers | 10/1/2023 | vs | W 35-16 | 5 | 30 | 395 | 362 | 60.0 | 100.0 | ||
| 6 | | 49ers | 12/17/2023 | @ | W 45-29 | 6 | 24 | 406 | 436 | 57.1 | |||
| 7 | | 49ers | 10/6/2024 | vs | L 23-24 | 2 | 22 | 384 | 358 | 54.5 | 0.0 | ||
| 8 | | 49ers | 1/5/2025 | @ | L 24-47 | 3 | 26 | 436 | 393 | 38.5 | 50.0 | ||
| 9 | | 49ers | 9/21/2025 | vs | W 16-15 | 1 | 19 | 355 | 260 | 20.0 | 50.0 | ||
| 10 | | 49ers | 11/16/2025 | @ | W 41-22 | 5 | 24 | 281 | 488 | 33.3 | |||
| Average | 3.5 | 22.8 | 363.0 | 360.7 | 42.0 | 0.1 | |||||||
| Total | 35 | 228 | 3,630 | 3,607 | 42.0 | 33.3 |
SF
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More 49ers Stats
Team Leaders 
PASS
492
Purdy
RUSH
91
McCaffrey
REC
103
Evans
Team Rankings
PPG
31.0
4th
OPP PPG
10.0
3rd
RUSH YDS/G
134.5
8th
PASS YDS/G
246.0
10th
Seahawks
Rams
DEN
WAS
ATL
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
| NFC North | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
1 | 2 | 0 | .333 | |
| NFC South | W | L | T | PCT |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
1 | 2 | 0 | .333 | |
0 | 2 | 0 | .000 | |
| NFC West | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 |
Eagles
Giants
Cowboys
Vikings
Lions
Bears
Packers
Panthers
Saints
Buccaneers| AFC East | W | L | T | PCT |
|---|---|---|---|---|
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
| AFC North | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
| AFC South | W | L | T | PCT |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
0 | 2 | 0 | .000 | |
0 | 2 | 0 | .000 | |
| AFC West | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 |
Bills
Patriots
Jets
Dolphins
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Ravens
Steelers
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Jaguars
Titans
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