Derrick Henry rushed for his most yards in a game against the Texans on January 3, 2021, with 250 yards.

Interpreted as:

Derrick Henry most rushing yards in a regular-season game record

	NAME	RUSH YDS	DATE	TM		OPP	ATT	YPC	RUSH TD	REC YDS	REC	TRG	AVG	REC TD
1	Derrick Henry D. Henry	250	1/3/2021	TEN	@	HOU	34	7.4	2	0	0	0		0
2	Derrick Henry D. Henry	238	12/6/2018	TEN	vs	JAX	17	14.0	4	0	0	0		0
3	Derrick Henry D. Henry	219	10/30/2022	TEN	@	HOU	32	6.8	2	9	1	1	9.0	0
4	Derrick Henry D. Henry	216	12/27/2025	BAL	@	GB	36	6.0	4	0	0	0		0
5	Derrick Henry D. Henry	215	12/13/2020	TEN	@	JAX	26	8.3	2	7	2	2	3.5	0
6	Derrick Henry D. Henry	212	10/18/2020	TEN	vs	HOU	22	9.6	2	52	2	5	26.0	0
7	Derrick Henry D. Henry	211	12/29/2019	TEN	@	HOU	32	6.6	3	0	0	0		0
8	Derrick Henry D. Henry	199	9/29/2024	BAL	vs	BUF	24	8.3	1	10	3	3	3.3	1
9	Derrick Henry D. Henry	188	11/10/2019	TEN	vs	KC	23	8.2	2	3	2	2	1.5	0
10	Derrick Henry D. Henry	182	9/19/2021	TEN	@	SEA	35	5.2	3	55	6	6	9.2	0
11	Derrick Henry D. Henry	178	11/29/2020	TEN	@	IND	27	6.6	3	7	2	4	3.5	0
12	Derrick Henry D. Henry	170	12/16/2018	TEN	@	NYG	33	5.2	2	0	1	1	0.0	0
13	Derrick Henry D. Henry	169	9/7/2025	BAL	@	BUF	18	9.4	2	13	1	1	13.0	0
14	Derrick Henry D. Henry	169	10/21/2024	BAL	@	TB	15	11.3	0	13	1	1	13.0	1
15	Derrick Henry D. Henry	162	12/21/2024	BAL	vs	PIT	24	6.8	0	27	2	2	13.5	0
16	Derrick Henry D. Henry	159	11/24/2019	TEN	vs	JAX	19	8.4	2	16	1	1	16.0	0
17	Derrick Henry D. Henry	157	10/3/2021	TEN	@	NYJ	33	4.8	1	20	2	2	10.0	0
18	Derrick Henry D. Henry	153	1/7/2024	TEN	vs	JAX	19	8.1	1	0	0	0		0
19	Derrick Henry D. Henry	151	9/22/2024	BAL	@	DAL	25	6.0	2	23	1	1	23.0	0
20	Derrick Henry D. Henry	149	12/1/2019	TEN	@	IND	26	5.7	1	17	3	3	5.7	0
21	Derrick Henry D. Henry	147	12/25/2024	BAL	@	HOU	27	5.4	1	18	2	2	9.0	0
22	Derrick Henry D. Henry	147	12/20/2020	TEN	vs	DET	24	6.1	1	5	2	2	2.5	0
23	Derrick Henry D. Henry	143	10/18/2021	TEN	vs	BUF	20	7.2	3	13	2	3	6.5	0
24	Derrick Henry D. Henry	140	11/25/2024	BAL	@	LAC	24	5.8	0	0	0	0		0
25	Derrick Henry D. Henry	138	1/4/2025	BAL	vs	CLE	20	6.9	2	23	2	3	11.5	0

Unlock 2x data

Results may be incomplete. StatMuse has complete game-level data for rushing yards going back to the 1960 season.

More Titans Stats

Team Leaders

PASS

3,169

Ward

RUSH

1,082

Pollard

REC

560

Okonkwo

Team Rankings

PPG

16.7

30th

OPP PPG

28.1

28th

RUSH YDS/G

93.5

30th

PASS YDS/G

190.6

29th

2025 Division Standings

TEAM	W	L	PCT
Jaguars	13	4	.765
Texans	12	5	.706
Colts	8	9	.471
Titans	3	14	.176

Last Game

Titans

3 - 14

Final

Jaguars

13 - 4

Sun 4 Jan 2026

NFL 2025 Leaders

Pass Yards Leaders

4,707

Stafford

4,564

Goff

4,552

Prescott

Rush Yards Leaders

1,621

Cook

1,595

Henry

1,585

Taylor

Rec Yards Leaders

1,793

Smith-Njigba

1,715

Nacua

1,429

Pickens

Pass TD Leaders

46

Stafford

34

Goff

31

Maye

Rush TD Leaders

18

Taylor

16

Henry

14

Allen

Rec TD Leaders

14

Adams

11

McBride

11

St. Brown

QB Rating Leaders

113.5

Maye

109.2

Stafford

105.5

Goff

Sack Leaders

23.0

Garrett

16.5

Burns

15.0

Hunter

NFL 2025 Rankings

PPG Rankings

30.5

28.8

28.4

28.3

27.9

Opp PPG Rankings

17.2

17.4

18.3

18.8

19.1

19.3

Total Yards Rankings

394.6

391.9

379.4

376.3

373.2

369.5

Rush Yards Rankings

159.6

156.6

144.5

134.7

129.1

128.9

Pass Yards Rankings

278.5

276.9

268.6

262.3

256.1

254.0

Sack Leaders

68.0

57.0

53.0

49.0

48.0

NFL Fantasy 2025

Fantasy RB Rankings

316.3

Taylor

314.6

McCaffrey

291.8

Robinson

Fantasy WR Rankings

246

Nacua

240.9

Smith-Njigba

207

St. Brown

Fantasy TE Rankings

189.9

McBride

125.1

Goedert

122.8

Pitts

Fantasy K Rankings

202

Myers

194

Fairbairn

187.6

Aubrey

NFL 2025 Betting

Best Record ATS

12-5

11-6

10-6-1

Worst Record ATS

5-12

5-11-1

6-11

7-10

NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - y	14	3	0	.824
Bills - w	12	5	0	.706
Dolphins - e	7	10	0	.412
Jets - e	3	14	0	.176
AFC North	W	L	T	PCT
Steelers - y	10	7	0	.588
Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
AFC South	W	L	T	PCT
Jaguars - y	13	4	0	.765
Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
Titans - e	3	14	0	.176
AFC West	W	L	T	PCT
Broncos - z*	14	3	0	.824
Chargers - w	11	6	0	.647
Chiefs - e	6	11	0	.353
Raiders - e	3	14	0	.176

NFC East	W	L	T	PCT
Eagles - y	11	6	0	.647
Cowboys - e	7	9	1	.441
Commanders - e	5	12	0	.294
Giants - e	4	13	0	.235
NFC North	W	L	T	PCT
Bears - y	11	6	0	.647
Packers - w	9	7	1	.559
Vikings - e	9	8	0	.529
Lions - e	9	8	0	.529
NFC South	W	L	T	PCT
Panthers - y	8	9	0	.471
Buccaneers - e	8	9	0	.471
Falcons - e	8	9	0	.471
Saints - e	6	11	0	.353
NFC West	W	L	T	PCT
Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
49ers - w	12	5	0	.706
Cardinals - e	3	14	0	.176