Between the 2000 and 2020 seasons, Calvin Johnson had the most games with 200+ receiving yards, with 5 games.

most 200 yard receiving games 2000 to 2020
Interpreted as:
most 200 or more yard receiving regular-season games by a player 2000 to 2020
JohnsonCooperJonesJohnsonOwensHillBrownGreenHopkinsGordonJefferyWayneWhiteJohnsonBoldinBurressHoltWallerLockettKuppFullerKittleThomas53333222222222222111111
NAMEGPREC YDSRECTRGREC AVGREC YDS/GREC TDRUSH YDSATTRUSH AVGRUSH YDS/GRUSH TD
Calvin JohnsonCalvin Johnson51,219577721.4243.85000.00
Amari CooperAmari Cooper3653324620.4217.76000.00
Julio JonesJulio Jones3812354723.2270.7415115.05.00
Andre JohnsonAndre Johnson3709344720.9236.35000.00
Terrell OwensTerrell Owens3718375019.4239.33515.01.70
Tyreek HillTyreek Hill2484232921.0242.05000.00
Antonio BrownAntonio Brown2497284117.8248.5022211.011.00
A.J. GreenA.J. Green2451212821.5225.53000.00
DeAndre HopkinsDeAndre Hopkins2462172027.2231.03000.00
Josh GordonJosh Gordon2498243220.8249.03000.00
Alshon JefferyAlshon Jeffery2467222821.2233.53010.00.00
Reggie WayneReggie Wayne2412274015.3206.02000.00
Roddy WhiteRoddy White2411192321.6205.54000.00
Chad JohnsonChad Johnson2469222821.3234.54010.00.00
Anquan BoldinAnquan Boldin2425233118.5212.53000.00
Plaxico BurressPlaxico Burress2457193024.1228.54000.00
Torry HoltTorry Holt2403182822.4201.53000.00
Darren WallerDarren Waller1200131715.4200.02000.00
Tyler LockettTyler Lockett1200152013.3200.03000.00
Cooper KuppCooper Kupp122071031.4220.01000.00
Will FullerWill Fuller1217141615.5217.03000.00
George KittleGeorge Kittle12107930.0210.01000.00
Michael ThomasMichael Thomas1211121517.6211.01000.00
Adam ThielenAdam Thielen1202121516.8202.02414.04.00
Odell Beckham Jr.Odell Beckham Jr.122281027.8222.02000.00
StatMuse has game-level data for receiving yards going back to the 1960 season.

Try also: