12 players are tied for the most interceptions by a defensive back in a game, with 4 interceptions. The first three are DeAngelo Hall on October 24, 2010, Deltha O'Neal on October 7, 2001 and Kwamie Lassiter on December 27, 1998.
Interpreted as:
most defensive interceptions in a regular-season game by any db| NAME | INT | DATE | TM | OPP | TKL | AST | COMB | SCK | SCKY | INT YDS | INT TD | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Hall | 4 | 10/24/2010 |  WAS | @ |  CHI | 7 | 0 | 7 | 0.0 | 0 | 92 | 1 | 0 | 0 | 0 |
| 2 | | D. O'Neal | 4 | 10/7/2001 |  DEN | vs |  KC | 3 | 0 | 3 | 0.0 | 0 | 69 | 0 | 0 | 0 | 0 |
| 3 | | K. Lassiter | 4 | 12/27/1998 |  ARI | vs |  SD | 0.0 | 36 | 0 | 0 | ||||||
| 4 | | D. Cherry | 4 | 9/29/1985 | KC | vs |  SEA | 0.0 | 24 | 0 | 0 | ||||||
| 5 | | W. Buchanon | 4 | 9/24/1978 |  GB | @ | SD | 77 | 1 | 0 | |||||||
| 6 | | D. Anderson | 4 | 12/3/1973 |  MIA | vs |  PIT | 121 | 2 | 0 | |||||||
| 7 | | W. Brown | 4 | 11/15/1964 | DEN | vs |  NYJ | 91 | 0 | 0 | |||||||
| 8 | | B. Hunt | 4 | 10/4/1964 | KC | vs |  HOU | 108 | 1 | 0 | |||||||
| 9 | | B. Ply | 4 | 12/16/1962 | DLT | vs | SD | 108 | 0 | 0 | |||||||
| 10 | | J. Norton | 4 | 11/26/1961 |  STL | @ | PIT | 110 | 2 | 0 | |||||||
| 11 | | D. Baker | 4 | 12/4/1960 |  SF | @ |  LA | 49 | 0 | 0 | |||||||
| 12 | | J. Norton | 4 | 11/20/1960 | STL | @ | WAS | 20 | 0 | 0 | |||||||
| 13 | | G. Gonsoulin | 4 | 9/18/1960 | DEN | @ |  BUF | 28 | 0 | 0 | |||||||
| 14 | | J. Whitehead | 3 | 9/11/2023 |  NYJ | vs | BUF | 1 | 1 | 2 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 15 | | A. Adams | 3 | 12/2/2018 |  TB | vs |  CAR | 1 | 0 | 1 | 0.0 | 0 | 21 | 0 | 0 | 0 | 0 |
| 16 | | K. Byard III | 3 | 10/22/2017 | TEN | @ |  CLE | 2 | 2 | 4 | 0.0 | 0 | 60 | 0 | 0 | 0 | 0 |
| 17 | | K. Coleman | 3 | 10/16/2011 |  PHI | @ | WAS | 5 | 2 | 7 | 0.0 | 0 | 25 | 0 | 0 | 0 | 0 |
| 18 | | G. Quin | 3 | 11/28/2010 |  HOU | vs | TEN | 3 | 1 | 4 | 0.0 | 0 | 12 | 0 | 0 | 0 | 0 |
| 19 | | L. Bodden | 3 | 11/22/2009 |  NE | vs |  NYJ | 3 | 0 | 3 | 0.0 | 0 | 60 | 1 | 0 | 0 | 0 |
| 20 | | A. Talib | 3 | 10/4/2009 | TB | @ | WAS | 4 | 0 | 4 | 0.0 | 0 | 61 | 0 | 0 | 0 | 0 |
| 21 | | L. Hall | 3 | 12/21/2008 |  CIN | @ | CLE | 1 | 1 | 2 | 0.0 | 0 | 87 | 1 | 0 | 0 | 0 |
| 22 | | M. Trufant | 3 | 12/9/2007 | SEA | vs | ARI | 4 | 2 | 6 | 0.0 | 0 | 96 | 1 | 0 | 0 | 0 |
| 23 | | A. Rolle | 3 | 11/18/2007 | ARI | @ | CIN | 3 | 1 | 4 | 0.0 | 0 | 127 | 2 | 0 | 0 | 0 |
| 24 | | A. Cromartie | 3 | 11/11/2007 | SD | vs |  IND | 6 | 0 | 6 | 0.0 | 0 | 27 | 0 | 0 | 0 | 0 |
| 25 | | A. Samuel | 3 | 11/26/2006 | NE | vs | CHI | 8 | 0 | 8 | 0.0 | 0 | 26 | 0 | 0 | 0 | 0 |
Results may be incomplete. StatMuse has complete game-level data for interceptions going back to the 1960 season.
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