Lito Sheppard has defended the most passes in a game, with 7 passes defended versus the Cowboys on October 8, 2006.
Interpreted as:
most passes defended by a player in a regular-season game| NAME | PDEF | DATE | TM | OPP | TKL | AST | COMB | SCK | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | L. Sheppard | 7 | 10/8/2006 |  PHI | vs |  DAL | 7 | 1 | 8 | 0.0 | 0 | 2 | 102 | 1 | 0 | 0 | 0 |
| 2 | | M. Lattimore | 6 | 10/10/2021 |  NO | @ |  WAS | 1 | 0 | 1 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3 | | K. Fuller | 6 | 12/24/2017 |  CHI | vs |  CLE | 1 | 0 | 1 | 0.0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
| 4 | | T. Johnson | 6 | 10/2/2016 |  LA | @ |  ARI | 5 | 0 | 5 | 0.0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
| 5 | | D. Amerson | 6 | 11/29/2015 |  OAK | @ |  TEN | 2 | 0 | 2 | 0.0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 |
| 6 | | T. McBride | 6 | 12/29/2013 |  NYG | vs | WAS | 0 | 0 | 0 | 0.0 | 0 | 2 | 17 | 0 | 0 | 0 | 0 |
| 7 | | L. Webb | 6 | 11/10/2013 |  BAL | vs |  CIN | 2 | 3 | 5 | 0.0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
| 8 | | T. Brown | 6 | 10/29/2012 |  SF | @ | ARI | 1 | 0 | 1 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | | B. Grimes | 6 | 12/5/2010 |  ATL | @ |  TB | 6 | 1 | 7 | 0.0 | 0 | 1 | 33 | 0 | 0 | 0 | 0 |
| 10 | | T. McGee | 6 | 11/17/2008 |  BUF | vs | CLE | 6 | 0 | 6 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 11 | | F. Brown | 6 | 10/7/2007 | STL | vs | ARI | 9 | 0 | 9 | 0.0 | 0 | 2 | 12 | 0 | 0 | 0 | 0 |
| 12 | | C. Rogers | 6 | 11/12/2006 | WAS | @ | PHI | 4 | 1 | 5 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | | M. McKenzie | 6 | 9/14/2003 |  GB | vs |  DET | 3 | 0 | 3 | 0.0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
| 14 | | C. Bailey | 6 | 11/17/2002 | WAS | @ | NYG | 7 | 0 | 7 | 0.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
| 15 | | R. Barber | 6 | 9/15/2002 | TB | @ | BAL | 3 | 2 | 5 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | | A. Glenn | 6 | 9/8/2002 |  HOU | vs | DAL | 5 | 0 | 5 | 0.0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
| 17 | | D. O'Neal | 6 | 10/7/2001 |  DEN | vs |  KC | 3 | 0 | 3 | 0.0 | 0 | 4 | 69 | 0 | 0 | 0 | 0 |
| 18 | | DJ Turner II | 5 | 10/12/2025 | CIN | @ | GB | 3 | 1 | 4 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 19 | | Q. Mitchell | 5 | 9/28/2025 | PHI | @ | TB | 4 | 1 | 5 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | | K. Nixon | 5 | 9/11/2025 | GB | vs |  WAS | 2 | 0 | 2 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 | | J. Bradberry IV | 5 | 11/26/2023 | PHI | vs | BUF | 3 | 0 | 3 | 0.0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 |
| 22 | | A. Taylor | 5 | 9/24/2023 | NO | @ | GB | 5 | 0 | 5 | 1.0 | 14 | 0 | 0 | 0 | 0 | 0 | 0 |
| 23 | | D. Slay | 5 | 9/19/2022 | PHI | vs |  MIN | 1 | 0 | 1 | 0.0 | 0 | 2 | 19 | 0 | 0 | 0 | 0 |
| 24 | | J. Jenkins | 5 | 11/22/2020 | NO | vs | ATL | 4 | 1 | 5 | 0.0 | 0 | 1 | 3 | 0 | 0 | 0 | 0 |
| 25 | | E. Rowe | 5 | 11/1/2020 |  MIA | vs |  LAR | 5 | 2 | 7 | 0.0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 |
StatMuse has game-level data for passes defended going back to the 2001 season.
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|---|---|---|---|---|
| Eagles | 8 | 2 | 0 | .800 |
| Cowboys | 4 | 5 | 1 | .450 |
| Commanders | 3 | 8 | 0 | .273 |
| Giants | 2 | 10 | 0 | .167 |
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