Patrick Mahomes had the most passing touchdowns by a quarterback in his 2nd season, with 50 touchdowns.
| NAME | TD | SEASON | TM | GP | CMP | ATT | PCT | YDS | AVG | YDS/G | INT | RTG | TD% | INT% | SCK | SCKY | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | P. Mahomes | 50 | 2018 |  KC | 16 | 383 | 580 | 66.0 | 5,097 | 8.8 | 318.6 | 12 | 113.8 | 8.6 | 2.1 | 26 | 171 |
| 2 |  | D. Marino | 48 | 1984 |  MIA | 16 | 362 | 564 | 64.2 | 5,084 | 9.0 | 317.8 | 17 | 108.9 | 8.5 | 3.0 | 13 | 120 |
| 3 |  | K. Warner | 41 | 1999 |  STL | 16 | 325 | 499 | 65.1 | 4,353 | 8.7 | 272.1 | 13 | 109.2 | 8.2 | 2.6 | 29 | 201 |
| 4 |  | J. Herbert | 38 | 2021 |  LAC | 17 | 443 | 672 | 65.9 | 5,014 | 7.5 | 294.9 | 15 | 97.7 | 5.7 | 2.2 | 31 | 214 |
| 5 |  | L. Jackson | 36 | 2019 |  BAL | 15 | 265 | 401 | 66.1 | 3,127 | 7.8 | 208.5 | 6 | 113.3 | 9.0 | 1.5 | 23 | 106 |
| 6 |  | B. Bortles | 35 | 2015 |  JAX | 16 | 355 | 606 | 58.6 | 4,428 | 7.3 | 276.8 | 18 | 88.2 | 5.8 | 3.0 | 51 | 320 |
| 7 |  | J. Burrow | 34 | 2021 |  CIN | 16 | 366 | 520 | 70.4 | 4,611 | 8.9 | 288.2 | 14 | 108.3 | 6.5 | 2.7 | 51 | 370 |
| 8 |  | C. Wentz | 33 | 2017 |  PHI | 13 | 265 | 440 | 60.2 | 3,296 | 7.5 | 253.5 | 7 | 101.9 | 7.5 | 1.6 | 28 | 162 |
| 9 |  | D. Culpepper | 33 | 2000 |  MIN | 16 | 297 | 474 | 62.7 | 3,937 | 8.3 | 246.1 | 16 | 98.0 | 7.0 | 3.4 | 34 | 181 |
| 10 |  | D. Carr | 32 | 2015 |  OAK | 16 | 350 | 573 | 61.1 | 3,987 | 7.0 | 249.2 | 13 | 91.1 | 5.6 | 2.3 | 31 | 230 |
| 11 |  | C. Palmer | 32 | 2005 | CIN | 16 | 345 | 509 | 67.8 | 3,836 | 7.5 | 239.8 | 12 | 101.1 | 6.3 | 2.4 | 19 | 105 |
| 12 |  | B. Purdy | 31 | 2023 |  SF | 16 | 308 | 444 | 69.4 | 4,280 | 9.6 | 267.5 | 11 | 113.0 | 7.0 | 2.5 | 28 | 153 |
| 13 | | J. Garcia | 31 | 2000 | SF | 16 | 355 | 561 | 63.3 | 4,278 | 7.6 | 267.4 | 10 | 97.6 | 5.5 | 1.8 | 24 | 155 |
| 14 | | D. Anderson | 29 | 2007 |  CLE | 16 | 298 | 527 | 56.5 | 3,787 | 7.2 | 236.7 | 19 | 82.5 | 5.5 | 3.6 | 14 | 109 |
| 15 |  | J. Goff | 28 | 2017 |  LAR | 15 | 296 | 477 | 62.1 | 3,804 | 8.0 | 253.6 | 7 | 100.5 | 5.9 | 1.5 | 25 | 172 |
| 16 |  | J. Winston | 28 | 2016 |  TB | 16 | 345 | 567 | 60.8 | 4,090 | 7.2 | 255.6 | 18 | 86.1 | 4.9 | 3.2 | 35 | 239 |
| 17 |  | N. Foles | 27 | 2013 | PHI | 13 | 203 | 317 | 64.0 | 2,891 | 9.1 | 222.4 | 2 | 119.2 | 8.5 | 0.6 | 28 | 173 |
| 18 |  | A. Dalton | 27 | 2012 | CIN | 16 | 329 | 528 | 62.3 | 3,669 | 6.9 | 229.3 | 16 | 87.4 | 5.1 | 3.0 | 46 | 229 |
| 19 | | B. Esiason | 27 | 1985 | CIN | 15 | 251 | 431 | 58.2 | 3,443 | 8.0 | 229.5 | 12 | 93.2 | 6.3 | 2.8 | 32 | 289 |
| 20 |  | K. Murray | 26 | 2020 |  ARI | 16 | 375 | 558 | 67.2 | 3,971 | 7.1 | 248.2 | 12 | 94.3 | 4.7 | 2.2 | 27 | 176 |
| 21 |  | D. Watson | 26 | 2018 |  HOU | 16 | 345 | 505 | 68.3 | 4,165 | 8.2 | 260.3 | 9 | 103.1 | 5.1 | 1.8 | 62 | 384 |
| 22 |  | M. Mariota | 26 | 2016 |  TEN | 15 | 276 | 451 | 61.2 | 3,426 | 7.6 | 228.4 | 9 | 95.6 | 5.8 | 2.0 | 23 | 156 |
| 23 |  | R. Wilson | 26 | 2013 |  SEA | 16 | 257 | 407 | 63.1 | 3,357 | 8.2 | 209.8 | 9 | 101.2 | 6.4 | 2.2 | 44 | 272 |
| 24 | | A. Brooks | 26 | 2001 |  NO | 16 | 312 | 558 | 55.9 | 3,832 | 6.9 | 239.5 | 22 | 76.4 | 4.7 | 3.9 | 50 | 330 |
| 25 |  | P. Manning | 26 | 1999 |  IND | 16 | 331 | 533 | 62.1 | 4,135 | 7.8 | 258.4 | 15 | 90.7 | 4.9 | 2.8 | 14 | 116 |
StatMuse has season-level data for passing touchdowns going back to the 1921 season.
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PASS YDS/G
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