Drew Brees has the most career passing touchdowns against the Panthers, with 55 touchdowns.

Interpreted as:

most passing touchdowns by a player vs panthers

	NAME	TD	GP	CMP	ATT	PCT	YDS	AVG	YDS/G	INT	RTG	TD%	INT%	SCK	SCKY
1	Drew Brees D. Brees	55	28	737	1,083	68.1	7,949	7.3	283.9	21	98.2	5.1	1.9	43	290
2	Matt Ryan M. Ryan	41	28	638	968	65.9	7,463	7.7	266.5	20	94.6	4.2	2.1	65	426
3	Brett Favre B. Favre	23	10	227	365	62.2	2,609	7.1	260.9	13	89.9	6.3	3.6	22	162
4	Tom Brady T. Brady	17	11	284	425	66.8	3,101	7.3	281.9	6	95.6	4.0	1.4	14	94
5	Aaron Rodgers A. Rodgers	16	7	155	248	62.5	1,896	7.6	270.9	5	99.1	6.5	2.0	20	151
6	Jeff Garcia J. Garcia	16	10	214	357	59.9	2,526	7.1	252.6	6	89.5	4.5	1.7	17	98
7	Eli Manning E. Manning	15	8	173	273	63.4	1,890	6.9	236.3	9	88.3	5.5	3.3	18	119
8	Chris Chandler C. Chandler	14	12	172	277	62.1	2,272	8.2	189.3	13	85.3	5.1	4.7	30	243
9	Aaron Brooks A. Brooks	13	9	160	300	53.3	1,949	6.5	216.6	8	76.9	4.3	2.7	18	106
10	Matthew Stafford M. Stafford	12	7	163	250	65.2	1,749	7.0	249.9	6	91.6	4.8	2.4	21	142
11	Kurt Warner K. Warner	12	8	155	236	65.7	1,829	7.8	228.6	18	74.3	5.1	7.6	12	88
12	Brad Johnson B. Johnson	12	9	174	306	56.9	2,046	6.7	227.3	4	85.0	3.9	1.3	16	102
13	Baker Mayfield B. Mayfield	10	7	134	196	68.4	1,519	7.8	217.0	5	97.7	5.1	2.6	15	100
14	Kirk Cousins K. Cousins	10	8	163	240	67.9	1,643	6.8	205.4	4	94.1	4.2	1.7	10	69
15	Jameis Winston J. Winston	10	13	237	392	60.5	2,931	7.5	225.5	18	73.0	2.6	4.6	37	246
16	Russell Wilson R. Wilson	10	8	169	248	68.1	2,025	8.2	253.1	4	99.6	4.0	1.6	19	126
17	Steve Young S. Young	10	6	134	203	66.0	1,582	7.8	263.7	5	95.7	4.9	2.5	15	53
18	Kyler Murray K. Murray	9	5	114	163	69.9	935	5.7	187.0	5	89.9	5.5	3.1	14	82
19	Dak Prescott D. Prescott	9	4	83	123	67.5	808	6.6	202.0	0	110.1	7.3	0.0	6	32
20	Derek Carr D. Carr	9	6	124	184	67.4	1,337	7.3	222.8	3	98.0	4.9	1.6	8	50
21	Josh Freeman J. Freeman	9	6	122	200	61.0	1,400	7.0	233.3	8	80.4	4.5	4.0	9	50
22	Ben Roethlisberger B. Roethlisberger	9	4	76	104	73.1	969	9.3	242.3	0	130.6	8.7	0.0	8	61
23	Josh McCown J. McCown	8	5	97	170	57.1	1,214	7.1	242.8	7	77.9	4.7	4.1	15	92
24	Tua Tagovailoa T. Tagovailoa	7	3	75	98	76.5	748	7.6	249.3	0	121.5	7.1	0.0	5	53
25	Patrick Mahomes P. Mahomes	7	2	57	82	69.5	641	7.8	320.5	0	121.0	8.5	0.0	7	54

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StatMuse has game-level data for passing touchdowns going back to the 1950 season.

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