Kyler Murray had the most passing yards by a quarterback in a Week-2 game in 2021, with 400 yards versus the Vikings on September 19, 2021.
| NAME | YDS | DATE | TM | OPP | CMP | ATT | PCT | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | K. Murray | 400 | 9/19/2021 | vs | 29 | 36 | 80.6 | 11.1 | 3 | 2 | 117.6 | 8.3 | 5.6 | 3 | 29 | ||
| 2 |  | D. Carr | 382 | 9/19/2021 | @ | 28 | 37 | 75.7 | 10.3 | 2 | 0 | 126.2 | 5.4 | 0.0 | 2 | 9 | ||
| 3 |  | R. Tannehill | 347 | 9/19/2021 | @ | 27 | 40 | 67.5 | 8.7 | 0 | 0 | 94.5 | 0.0 | 0.0 | 3 | 27 | ||
| 4 |  | R. Wilson | 343 | 9/19/2021 | vs | 22 | 31 | 71.0 | 11.1 | 2 | 0 | 128.8 | 6.5 | 0.0 | 3 | 23 | ||
| 5 |  | P. Mahomes | 343 | 9/19/2021 | @ | 24 | 31 | 77.4 | 11.1 | 3 | 1 | 131.5 | 9.7 | 3.2 | 0 | 0 | ||
| 6 |  | J. Herbert | 338 | 9/19/2021 | vs | 31 | 41 | 75.6 | 8.2 | 1 | 2 | 87.2 | 2.4 | 4.9 | 2 | 25 | ||
| 7 |  | T. Heinicke | 336 | 9/16/2021 | vs | 34 | 46 | 73.9 | 7.3 | 2 | 1 | 99.5 | 4.3 | 2.2 | 1 | 16 | ||
| 8 |  | T. Bridgewater | 328 | 9/19/2021 | @ | 26 | 34 | 76.5 | 9.6 | 2 | 0 | 125.6 | 5.9 | 0.0 | 3 | 26 | ||
| 9 |  | S. Darnold | 305 | 9/19/2021 | vs | 26 | 38 | 68.4 | 8.0 | 2 | 1 | 99.1 | 5.3 | 2.6 | 2 | 11 | ||
| 10 |  | M. Ryan | 300 | 9/19/2021 | @ | 35 | 46 | 76.1 | 6.5 | 2 | 3 | 80.0 | 4.3 | 6.5 | 1 | 7 | ||
| 11 |  | B. Roethlisberger | 295 | 9/19/2021 | vs | 27 | 40 | 67.5 | 7.4 | 1 | 1 | 87.0 | 2.5 | 2.5 | 2 | 3 | ||
| 12 |  | M. Stafford | 278 | 9/19/2021 | @ | 19 | 30 | 63.3 | 9.3 | 2 | 1 | 101.8 | 6.7 | 3.3 | 1 | 8 | ||
| 13 |  | T. Brady | 276 | 9/19/2021 | vs | 24 | 36 | 66.7 | 7.7 | 5 | 0 | 129.2 | 13.9 | 0.0 | 3 | 17 | ||
| 14 |  | A. Rodgers | 255 | 9/20/2021 | vs | 22 | 27 | 81.5 | 9.4 | 4 | 0 | 145.6 | 14.8 | 0.0 | 3 | 28 | ||
| 15 |  | D. Jones | 249 | 9/16/2021 | @ | 22 | 32 | 68.8 | 7.8 | 1 | 0 | 102.2 | 3.1 | 0.0 | 4 | 21 | ||
| 16 |  | C. Wentz | 247 | 9/19/2021 | vs | 20 | 31 | 64.5 | 8.0 | 1 | 1 | 86.4 | 3.2 | 3.2 | 3 | 27 | ||
| 17 |  | J. Goff | 246 | 9/20/2021 | @ | 26 | 36 | 72.2 | 6.8 | 2 | 1 | 97.7 | 5.6 | 2.8 | 1 | 10 | ||
| 18 |  | K. Cousins | 244 | 9/19/2021 | @ | 22 | 32 | 68.8 | 7.6 | 3 | 0 | 122.4 | 9.4 | 0.0 | 1 | 2 | ||
| 19 |  | L. Jackson | 239 | 9/19/2021 | vs | 18 | 26 | 69.2 | 9.2 | 1 | 2 | 78.8 | 3.8 | 7.7 | 1 | 9 | ||
| 20 |  | D. Prescott | 237 | 9/19/2021 | @ | 23 | 27 | 85.2 | 8.8 | 0 | 1 | 87.8 | 0.0 | 3.7 | 2 | 16 | ||
| 21 |  | B. Mayfield | 213 | 9/19/2021 | vs | 19 | 21 | 90.5 | 10.1 | 1 | 1 | 105.0 | 4.8 | 4.8 | 2 | 14 | ||
| 22 |  | Z. Wilson | 210 | 9/19/2021 | vs | 19 | 33 | 57.6 | 6.4 | 0 | 4 | 37.0 | 0.0 | 12.1 | 4 | 26 | ||
| 23 |  | J. Burrow | 207 | 9/19/2021 | @ | 19 | 30 | 63.3 | 6.9 | 2 | 3 | 66.3 | 6.7 | 10.0 | 5 | 28 | ||
| 24 |  | J. Hurts | 190 | 9/19/2021 | vs | 12 | 23 | 52.2 | 8.3 | 0 | 0 | 80.0 | 0.0 | 0.0 | 2 | 13 | ||
| 25 |  | J. Garoppolo | 189 | 9/19/2021 | @ | 22 | 30 | 73.3 | 6.3 | 1 | 0 | 100.6 | 3.3 | 0.0 | 0 | 0 | ||
PIT
BAL
WAS
CAR
TB
NYJ
CHIMore Cardinals Stats
Team Leaders 
PASS
3,123
Brissett
RUSH
315
Carter
REC
1,174
McBride
Team Rankings
PPG
20.9
23rd
OPP PPG
28.2
29th
RUSH YDS/G
94.0
29th
PASS YDS/G
255.2
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 13 | 3 | 0 | .813 |
 Bills - w | 11 | 5 | 0 | .688 |
 Dolphins - e | 7 | 9 | 0 | .438 |
 Jets - e | 3 | 13 | 0 | .188 |
| AFC North | W | L | T | PCT |
9 | 7 | 0 | .563 | |
8 | 8 | 0 | .500 | |
 Bengals - e | 6 | 10 | 0 | .375 |
 Browns - e | 4 | 12 | 0 | .250 |
| AFC South | W | L | T | PCT |
 Jaguars - x | 12 | 4 | 0 | .750 |
 Texans - x | 11 | 5 | 0 | .688 |
 Colts - e | 8 | 8 | 0 | .500 |
 Titans - e | 3 | 13 | 0 | .188 |
| AFC West | W | L | T | PCT |
 Broncos - y | 13 | 3 | 0 | .813 |
 Chargers - w | 11 | 5 | 0 | .688 |
 Chiefs - e | 6 | 10 | 0 | .375 |
 Raiders - e | 2 | 14 | 0 | .125 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 5 | 0 | .688 |
 Cowboys - e | 7 | 8 | 1 | .469 |
 Commanders - e | 4 | 12 | 0 | .250 |
 Giants - e | 3 | 13 | 0 | .188 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 5 | 0 | .688 |
 Packers - w | 9 | 6 | 1 | .594 |
 Vikings - e | 8 | 8 | 0 | .500 |
 Lions - e | 8 | 8 | 0 | .500 |
| NFC South | W | L | T | PCT |
8 | 8 | 0 | .500 | |
7 | 9 | 0 | .438 | |
 Falcons - e | 7 | 9 | 0 | .438 |
 Saints - e | 6 | 10 | 0 | .375 |
| NFC West | W | L | T | PCT |
 Seahawks - x | 13 | 3 | 0 | .813 |
 49ers - x | 12 | 4 | 0 | .750 |
 Rams - w | 11 | 5 | 0 | .688 |
 Cardinals - e | 3 | 13 | 0 | .188 |
