Kyler Murray had the most passing yards by a quarterback in a Week-2 game in 2021, with 400 yards against the Vikings on September 19, 2021.
| NAME | YDS | DATE | TM | OPP | CMP | ATT | PCT | AVG | TD | INT | RTG | TD% | INT% | SCK | SCKY | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | K. Murray | 400 | 9/19/2021 | vs | 29 | 36 | 80.6 | 11.1 | 3 | 2 | 117.6 | 8.3 | 5.6 | 3 | 29 | ||
| 2 |  | D. Carr | 382 | 9/19/2021 | @ | 28 | 37 | 75.7 | 10.3 | 2 | 0 | 126.2 | 5.4 | 0.0 | 2 | 9 | ||
| 3 |  | R. Tannehill | 347 | 9/19/2021 | @ | 27 | 40 | 67.5 | 8.7 | 0 | 0 | 94.5 | 0.0 | 0.0 | 3 | 27 | ||
| 4 |  | R. Wilson | 343 | 9/19/2021 | vs | 22 | 31 | 71.0 | 11.1 | 2 | 0 | 128.8 | 6.5 | 0.0 | 3 | 23 | ||
| 5 |  | P. Mahomes | 343 | 9/19/2021 | @ | 24 | 31 | 77.4 | 11.1 | 3 | 1 | 131.5 | 9.7 | 3.2 | 0 | 0 | ||
| 6 |  | J. Herbert | 338 | 9/19/2021 | vs | 31 | 41 | 75.6 | 8.2 | 1 | 2 | 87.2 | 2.4 | 4.9 | 2 | 25 | ||
| 7 |  | T. Heinicke | 336 | 9/16/2021 | vs | 34 | 46 | 73.9 | 7.3 | 2 | 1 | 99.5 | 4.3 | 2.2 | 1 | 16 | ||
| 8 |  | T. Bridgewater | 328 | 9/19/2021 | @ | 26 | 34 | 76.5 | 9.6 | 2 | 0 | 125.6 | 5.9 | 0.0 | 3 | 26 | ||
| 9 |  | S. Darnold | 305 | 9/19/2021 | vs | 26 | 38 | 68.4 | 8.0 | 2 | 1 | 99.1 | 5.3 | 2.6 | 2 | 11 | ||
| 10 |  | M. Ryan | 300 | 9/19/2021 | @ | 35 | 46 | 76.1 | 6.5 | 2 | 3 | 80.0 | 4.3 | 6.5 | 1 | 7 | ||
| 11 |  | B. Roethlisberger | 295 | 9/19/2021 | vs | 27 | 40 | 67.5 | 7.4 | 1 | 1 | 87.0 | 2.5 | 2.5 | 2 | 3 | ||
| 12 |  | M. Stafford | 278 | 9/19/2021 | @ | 19 | 30 | 63.3 | 9.3 | 2 | 1 | 101.8 | 6.7 | 3.3 | 1 | 8 | ||
| 13 |  | T. Brady | 276 | 9/19/2021 | vs | 24 | 36 | 66.7 | 7.7 | 5 | 0 | 129.2 | 13.9 | 0.0 | 3 | 17 | ||
| 14 |  | A. Rodgers | 255 | 9/20/2021 | vs | 22 | 27 | 81.5 | 9.4 | 4 | 0 | 145.6 | 14.8 | 0.0 | 3 | 28 | ||
| 15 |  | D. Jones | 249 | 9/16/2021 | @ | 22 | 32 | 68.8 | 7.8 | 1 | 0 | 102.2 | 3.1 | 0.0 | 4 | 21 | ||
| 16 |  | C. Wentz | 247 | 9/19/2021 | vs | 20 | 31 | 64.5 | 8.0 | 1 | 1 | 86.4 | 3.2 | 3.2 | 3 | 27 | ||
| 17 |  | J. Goff | 246 | 9/20/2021 | @ | 26 | 36 | 72.2 | 6.8 | 2 | 1 | 97.7 | 5.6 | 2.8 | 1 | 10 | ||
| 18 |  | K. Cousins | 244 | 9/19/2021 | @ | 22 | 32 | 68.8 | 7.6 | 3 | 0 | 122.4 | 9.4 | 0.0 | 1 | 2 | ||
| 19 |  | L. Jackson | 239 | 9/19/2021 | vs | 18 | 26 | 69.2 | 9.2 | 1 | 2 | 78.8 | 3.8 | 7.7 | 1 | 9 | ||
| 20 |  | D. Prescott | 237 | 9/19/2021 | @ | 23 | 27 | 85.2 | 8.8 | 0 | 1 | 87.8 | 0.0 | 3.7 | 2 | 16 | ||
| 21 |  | B. Mayfield | 213 | 9/19/2021 | vs | 19 | 21 | 90.5 | 10.1 | 1 | 1 | 105.0 | 4.8 | 4.8 | 2 | 14 | ||
| 22 |  | Z. Wilson | 210 | 9/19/2021 | vs | 19 | 33 | 57.6 | 6.4 | 0 | 4 | 37.0 | 0.0 | 12.1 | 4 | 26 | ||
| 23 |  | J. Burrow | 207 | 9/19/2021 | @ | 19 | 30 | 63.3 | 6.9 | 2 | 3 | 66.3 | 6.7 | 10.0 | 5 | 28 | ||
| 24 |  | J. Hurts | 190 | 9/19/2021 | vs | 12 | 23 | 52.2 | 8.3 | 0 | 0 | 80.0 | 0.0 | 0.0 | 2 | 13 | ||
| 25 |  | J. Garoppolo | 189 | 9/19/2021 | @ | 22 | 30 | 73.3 | 6.3 | 1 | 0 | 100.6 | 3.3 | 0.0 | 0 | 0 | ||
PIT
BAL
WAS
CAR
TB
NYJ
CHIMore Cardinals Stats
Team Leaders 
PASS
3,123
Brissett
RUSH
315
Carter
REC
1,174
McBride
Team Rankings
PPG
20.9
23rd
OPP PPG
28.2
29th
RUSH YDS/G
94.0
29th
PASS YDS/G
255.2
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 13 | 3 | 0 | .813 |
 Bills - w | 11 | 5 | 0 | .688 |
 Dolphins - e | 7 | 9 | 0 | .438 |
 Jets - e | 3 | 13 | 0 | .188 |
| AFC North | W | L | T | PCT |
9 | 7 | 0 | .563 | |
8 | 8 | 0 | .500 | |
 Bengals - e | 6 | 10 | 0 | .375 |
 Browns - e | 4 | 12 | 0 | .250 |
| AFC South | W | L | T | PCT |
 Jaguars - x | 12 | 4 | 0 | .750 |
 Texans - x | 11 | 5 | 0 | .688 |
 Colts - e | 8 | 8 | 0 | .500 |
 Titans - e | 3 | 13 | 0 | .188 |
| AFC West | W | L | T | PCT |
 Broncos - y | 13 | 3 | 0 | .813 |
 Chargers - w | 11 | 5 | 0 | .688 |
 Chiefs - e | 6 | 10 | 0 | .375 |
 Raiders - e | 2 | 14 | 0 | .125 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 5 | 0 | .688 |
 Cowboys - e | 7 | 8 | 1 | .469 |
 Commanders - e | 4 | 12 | 0 | .250 |
 Giants - e | 3 | 13 | 0 | .188 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 5 | 0 | .688 |
 Packers - w | 9 | 6 | 1 | .594 |
 Vikings - e | 8 | 8 | 0 | .500 |
 Lions - e | 8 | 8 | 0 | .500 |
| NFC South | W | L | T | PCT |
8 | 8 | 0 | .500 | |
7 | 9 | 0 | .438 | |
 Falcons - e | 7 | 9 | 0 | .438 |
 Saints - e | 6 | 10 | 0 | .375 |
| NFC West | W | L | T | PCT |
 Seahawks - x | 13 | 3 | 0 | .813 |
 49ers - x | 12 | 4 | 0 | .750 |
 Rams - w | 11 | 5 | 0 | .688 |
 Cardinals - e | 3 | 13 | 0 | .188 |
