Since 2001, the San Francisco 49ers have earned their most PPR fantasy points in a game versus the Saints on December 8, 2019, with 165 points.
Interpreted as:
most ppr points in one regular-season game by a 49ers since 2001| TEAM | FPTS (PPR) | DATE | TM | OPP | TD | OFF | |||
|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 165 | 12/8/2019 | @ | 6 | 516 | ||
| 2 | | 49ers | 148.5 | 10/7/2012 | vs | 6 | 621 | ||
| 3 | | 49ers | 147.8 | 12/22/2025 | @ | 6 | 440 | ||
| 4 | | 49ers | 147.8 | 11/17/2019 | vs | 5 | 442 | ||
| 5 | | 49ers | 142.6 | 12/7/2003 | vs | 7 | 496 | ||
| 6 | | 49ers | 141.2 | 10/14/2001 | @ | 5 | 517 | ||
| 7 | | 49ers | 140.1 | 10/10/2004 | vs | 3 | 448 | ||
| 8 | | 49ers | 139.7 | 9/8/2013 | vs | 4 | 494 | ||
| 9 | | 49ers | 139.6 | 9/15/2019 | @ | 5 | 571 | ||
| 10 | | 49ers | 139.4 | 12/28/2025 | vs | 6 | 496 | ||
| 11 | | 49ers | 139.2 | 12/30/2024 | vs | 5 | 475 | ||
| 12 | | 49ers | 135.6 | 12/3/2023 | @ | 6 | 456 | ||
| 13 | | 49ers | 131.3 | 12/14/2003 | @ | 5 | 502 | ||
| 14 | | 49ers | 131.1 | 12/8/2002 | @ | 4 | 401 | ||
| 15 | | 49ers | 131.1 | 12/17/2023 | @ | 6 | 406 | ||
| 16 | | 49ers | 126.5 | 10/31/2019 | @ | 4 | 411 | ||
| 17 | | 49ers | 126.4 | 10/8/2023 | vs | 6 | 421 | ||
| 18 | | 49ers | 126.1 | 12/14/2025 | vs | 4 | 430 | ||
| 19 | | 49ers | 125.8 | 11/18/2001 | @ | 3 | 417 | ||
| 20 | | 49ers | 125.8 | 9/21/2017 | vs | 5 | 421 | ||
| 21 | | 49ers | 125.7 | 12/20/2020 | @ | 4 | 458 | ||
| 22 | | 49ers | 125.5 | 10/10/2024 | @ | 4 | 483 | ||
| 23 | | 49ers | 125.3 | 10/2/2025 | @ | 2 | 407 | ||
| 24 | | 49ers | 124.3 | 9/27/2020 | @ | 4 | 420 | ||
| 25 | | 49ers | 123.8 | 9/12/2021 | @ | 5 | 442 | ||
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More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |