Derrick Henry has rushed for the most yards for the Titans in a game, with 250 yards versus the Texans on January 3, 2021.
Interpreted as:
most rushing yards by a titans player in a regular-season game| NAME | RUSH YDS | DATE | TM | OPP | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Henry | 250 | 1/3/2021 |  TEN | @ |  HOU | 34 | 7.4 | 2 | 0 | 0 | 0 | 0 | |
| 2 | | D. Henry | 238 | 12/6/2018 | TEN | vs |  JAX | 17 | 14.0 | 4 | 0 | 0 | 0 | 0 | |
| 3 |  | C. Johnson | 228 | 11/1/2009 | TEN | vs | JAX | 24 | 9.5 | 2 | 11 | 2 | 3 | 5.5 | 0 |
| 4 | | D. Henry | 219 | 10/30/2022 | TEN | @ | HOU | 32 | 6.8 | 2 | 9 | 1 | 1 | 9.0 | 0 |
| 5 |  | E. George | 216 | 8/31/1997 |  TEN | vs |  OAK | 35 | 6.2 | 1 | 0 | 0 | 0 | ||
| 6 | | B. Cannon | 216 | 12/10/1961 | HOU | @ |  NYT | 25 | 8.6 | 3 | 114 | 5 | 22.8 | 2 | |
| 7 | | D. Henry | 215 | 12/13/2020 | TEN | @ | JAX | 26 | 8.3 | 2 | 7 | 2 | 2 | 3.5 | 0 |
| 8 | | D. Henry | 212 | 10/18/2020 | TEN | vs | HOU | 22 | 9.6 | 2 | 52 | 2 | 5 | 26.0 | 0 |
| 9 | | D. Henry | 211 | 12/29/2019 | TEN | @ | HOU | 32 | 6.6 | 3 | 0 | 0 | 0 | 0 | |
| 10 | | E. Campbell | 206 | 11/16/1980 |  HOU | @ |  CHI | 31 | 6.6 | 0 | 0 | 0 | 0 | ||
| 11 | | E. Campbell | 203 | 12/21/1980 | HOU | vs |  MIN | 29 | 7.0 | 1 | -1 | 1 | -1.0 | 0 | |
| 12 | | E. Campbell | 203 | 10/19/1980 | HOU | vs |  TB | 33 | 6.2 | 0 | 8 | 1 | 8.0 | 0 | |
| 13 | | E. Campbell | 202 | 10/26/1980 | HOU | vs |  CIN | 27 | 7.5 | 2 | 0 | 0 | 0 | ||
| 14 | | E. George | 199 | 12/9/1999 | TEN | vs | OAK | 28 | 7.1 | 2 | 50 | 6 | 8 | 8.3 | 0 |
| 15 | | E. Campbell | 199 | 11/20/1978 | HOU | vs |  MIA | 28 | 7.1 | 4 | 0 | 0 | 0 | ||
| 16 | | C. Johnson | 197 | 9/20/2009 | TEN | vs | HOU | 16 | 12.3 | 2 | 87 | 9 | 11 | 9.7 | 1 |
| 17 | | C. Johnson | 195 | 10/21/2012 | TEN | @ |  BUF | 18 | 10.8 | 2 | 3 | 1 | 2 | 3.0 | 0 |
| 18 | | E. Campbell | 195 | 11/22/1979 | HOU | @ |  DAL | 33 | 5.9 | 2 | 0 | 0 | 0 | ||
| 19 | | G. Brown | 194 | 11/21/1993 | HOU | @ |  CLE | 34 | 5.7 | 1 | 28 | 2 | 14.0 | 0 | |
| 20 | | C. Johnson | 190 | 11/27/2011 | TEN | vs | TB | 23 | 8.3 | 0 | 3 | 1 | 2 | 3.0 | 0 |
| 21 | | D. Henry | 188 | 11/10/2019 | TEN | vs |  KC | 23 | 8.2 | 2 | 3 | 2 | 2 | 1.5 | 0 |
| 22 | | E. Campbell | 186 | 10/11/1981 | HOU | vs |  SEA | 39 | 4.8 | 2 | 16 | 3 | 5.3 | 0 | |
| 23 | | H. Granger | 183 | 12/4/1966 | HOU | vs |  SD | 19 | 9.6 | 0 | 3 | 2 | 1.5 | 0 | |
| 24 | | D. Henry | 182 | 9/19/2021 | TEN | @ | SEA | 35 | 5.2 | 3 | 55 | 6 | 6 | 9.2 | 0 |
| 25 | | E. Campbell | 182 | 10/4/1981 | HOU | vs | CIN | 37 | 4.9 | 1 | 3 | 1 | 3.0 | 0 | |
Results may be incomplete. StatMuse has complete game-level data for rushing yards going back to the 1960 season.
More Titans Stats
Team Rankings
PPG
12.8
32nd
OPP PPG
30.0
28th
RUSH YDS/G
87.0
28th
PASS YDS/G
153.5
31st
Colts 
ARI 
NE 
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 0 | 0 | 1.000 |
 Commanders | 2 | 2 | 0 | .500 |
| NFC North | W | L | T | PCT |
 Lions | 3 | 1 | 0 | .750 |
 Packers | 2 | 1 | 1 | .625 |
| NFC South | W | L | T | PCT |
| Buccaneers | 3 | 1 | 0 | .750 |
 Falcons | 2 | 2 | 0 | .500 |
| NFC West | W | L | T | PCT |
 49ers | 4 | 1 | 0 | .800 |
| Seahawks | 3 | 1 | 0 | .750 |
Steelers 
BAL 
NYG 
NO 
DEN 
