Derrick Thomas has the most sacks in a Week-1 game, with 6 sacks against the Oakland Raiders on September 6, 1998.
Interpreted as:
most defensive sacks by a player in week 1| NAME | SCK | DATE | TM | OPP | TKL | AST | COMB | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Thomas | 6.0 | 9/6/1998 |  KC | vs |  OAK | 0 | 0 | 0 | 0 | ||||||
| 2 |  | B. Gay | 5.5 | 9/4/1983 |  DET | @ |  TB | 0 | 0 | 0 | 0 | ||||||
| 3 |  | C. Jones | 5.0 | 9/12/2021 |  ARI | @ |  TEN | 6 | 0 | 6 | 46 | 0 | 0 | 0 | 2 | 0 | 0 |
| 4 | | C. Campbell | 4.0 | 9/10/2017 |  JAX | @ |  HOU | 4 | 2 | 6 | 17.5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | | C. Haley | 4.0 | 9/4/1994 |  DAL | @ |  PIT | 0 | 0 | 0 | 0 | ||||||
| 6 | | C. Banks | 4.0 | 9/6/1992 |  IND | vs |  CLE | 1 | 3 | 0 | 0 | ||||||
| 7 | | M. Gastineau | 4.0 | 9/2/1984 |  NYJ | @ | IND | 0 | 0 | 0 | 0 | ||||||
| 8 | | D. Betters | 4.0 | 9/4/1983 |  MIA | @ |  BUF | 0 | 0 | 0 | 0 | ||||||
| 9 | | J. Osborne | 4.0 | 9/4/1983 |  CHI | vs |  ATL | 0 | 0 | 0 | 0 | ||||||
| 10 | | C. Doleman | 3.5 | 9/3/1995 | ATL | vs |  CAR | 0 | 0 | 0 | 0 | ||||||
| 11 | | L. Marshall | 3.5 | 9/8/1985 |  NYG | vs |  PHI | 0 | 0 | 0 | 0 | ||||||
| 12 | | A. Taylor | 3.0 | 9/8/2024 |  NO | vs | CAR | 5 | 1 | 6 | 26 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | | G. Rousseau | 3.0 | 9/8/2024 | BUF | vs | ARI | 6 | 0 | 6 | 11 | 0 | 0 | 0 | 1 | 0 | 0 |
| 14 |  | T.J. Watt | 3.0 | 9/10/2023 | PIT | vs |  SF | 5 | 0 | 5 | 17 | 0 | 0 | 0 | 2 | 1 | 0 |
| 15 | | D. Jackson | 3.0 | 9/10/2023 | SF | @ | PIT | 3 | 0 | 3 | 20 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | | J. Hines-Allen | 3.0 | 9/10/2023 | JAX | @ | IND | 7 | 3 | 10 | 3 | 0 | 0 | 0 | 0 | 0 | 0 |
| 17 | | A. Highsmith | 3.0 | 9/11/2022 | PIT | @ |  CIN | 6 | 3 | 9 | 23 | 0 | 0 | 0 | 1 | 0 | 0 |
| 18 |  | K. Mack | 3.0 | 9/11/2022 |  LAC | vs | LV | 5 | 1 | 6 | 17 | 0 | 0 | 0 | 1 | 0 | 0 |
| 19 | | D. Kennard | 3.0 | 9/8/2019 | DET | @ | ARI | 4 | 0 | 4 | 19 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | | T.J. Watt | 3.0 | 9/9/2018 | PIT | @ | CLE | 7 | 3 | 10 | 16 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 |  | V. Miller | 3.0 | 9/9/2018 |  DEN | vs |  SEA | 6 | 1 | 7 | 19 | 0 | 0 | 0 | 2 | 1 | 0 |
| 22 |  | J. Houston | 3.0 | 9/8/2013 | KC | @ | JAX | 5 | 0 | 5 | 27 | 0 | 0 | 0 | 0 | 0 | 0 |
| 23 | | R. Quinn | 3.0 | 9/8/2013 |  STL | vs | ARI | 3 | 0 | 3 | 17 | 0 | 0 | 0 | 2 | 0 | 0 |
| 24 | | T. Suggs | 3.0 | 9/11/2011 |  BAL | vs | PIT | 5 | 0 | 5 | 25 | 0 | 0 | 0 | 2 | 0 | 0 |
| 25 |  | C. Matthews | 3.0 | 9/12/2010 |  GB | @ | PHI | 7 | 0 | 7 | 11 | 0 | 0 | 0 | 1 | 0 | 0 |
StatMuse has game-level data for sacks going back to the 1982 season.
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