8 players were tied for the most tackles for loss in a game in 2021, with 4 tackles. The first three are Uchenna Nwosu on January 9, 2022, Charles Harris on December 19, 2021 and Josh Hines-Allen on October 31, 2021.
Interpreted as:
most tackles for loss by a player single regular-season game in 2021 NFL| NAME | TFL | DATE | TM | OPP | TKL | AST | COMB | SCK | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | U. Nwosu | 4 | 1/9/2022 | @ | 6 | 1 | 7 | 1.0 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 2 | | C. Harris | 4 | 12/19/2021 | vs | 7 | 5 | 12 | 1.5 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 3 | | J. Hines-Allen | 4 | 10/31/2021 | @ | 5 | 1 | 6 | 2.0 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 4 |  | M. Parsons | 4 | 10/31/2021 | @ | 10 | 1 | 11 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 5 | | D. Davis | 4 | 10/25/2021 | @ | 7 | 3 | 10 | 2.0 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 6 | | N. Bolton | 4 | 10/24/2021 | @ | 9 | 6 | 15 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 7 |  | M. Garrett | 4 | 9/26/2021 | vs | 6 | 1 | 7 | 4.5 | 24.5 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 8 |  | C. Jones | 4 | 9/12/2021 | @ | 6 | 0 | 6 | 5.0 | 46 | 0 | 0 | 0 | 2 | 0 | 0 | ||
| 9 | | K. Seymour | 3 | 1/9/2022 | vs | 3 | 0 | 3 | 1.0 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 10 |  | V. Miller | 3 | 1/9/2022 | vs | 5 | 0 | 5 | 1.0 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 11 |  | M. Crosby | 3 | 1/9/2022 | vs | 6 | 1 | 7 | 2.0 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 12 |  | T.J. Watt | 3 | 1/3/2022 | vs | 5 | 0 | 5 | 4.0 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 13 | | A. Highsmith | 3 | 1/3/2022 | vs | 7 | 0 | 7 | 2.0 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 14 | | V. Miller | 3 | 1/2/2022 | @ | 5 | 0 | 5 | 2.0 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 15 | | C. Jordan | 3 | 1/2/2022 | vs | 6 | 2 | 8 | 3.5 | 21.5 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 16 | | F. Luvu | 3 | 1/2/2022 | @ | 6 | 3 | 9 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 17 |  | A. Donald | 3 | 12/26/2021 | @ | 5 | 1 | 6 | 1.0 | 11 | 0 | 0 | 0 | 1 | 0 | 0 | ||
| 18 | | C. Dunlap | 3 | 12/21/2021 | @ | 4 | 0 | 4 | 3.0 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 19 | | L. David | 3 | 12/19/2021 | vs | 8 | 3 | 11 | 1.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | ||
| 20 | | A. Donald | 3 | 12/13/2021 | @ | 3 | 2 | 5 | 3.0 | 35 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 21 | | D. Fowler Jr. | 3 | 12/12/2021 | @ | 3 | 0 | 3 | 1.0 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 22 | | T. Hill | 3 | 12/12/2021 | vs | 5 | 2 | 7 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 23 | | D. Jones | 3 | 12/12/2021 | vs | 3 | 0 | 3 | 2.0 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 24 | | A. Al-Shaair | 3 | 12/12/2021 | @ | 8 | 3 | 11 | 1.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 25 | | K. Grugier-Hill | 3 | 12/5/2021 | vs | 10 | 10 | 20 | 1.0 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | ||
CHIStatMuse has game-level data for tackles for loss going back to the 2001 season.
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| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |