J.J. Watt has the most tackles for loss by a defensive lineman in a season, with 39 tackles in 2012.
| NAME | TFL | SEASON | TM | GP | TKL | AST | COMB | SCK | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J.J. Watt | 39 | 2012 |  HOU | 16 | 69 | 12 | 81 | 20.5 | 138.5 | 0 | 0 | 0 | 4 | 2 | 0 |
| 2 | | J.J. Watt | 29 | 2015 | HOU | 16 | 57 | 19 | 76 | 17.5 | 117.5 | 0 | 0 | 0 | 3 | 1 | 0 |
| 3 | | J.J. Watt | 29 | 2014 | HOU | 16 | 59 | 19 | 78 | 20.5 | 140 | 1 | 80 | 1 | 4 | 5 | 1 |
| 4 |  | A. Donald | 25 | 2018 |  LAR | 16 | 41 | 18 | 59 | 20.5 | 183.5 | 0 | 0 | 0 | 4 | 2 | 0 |
| 5 |  | M. Strahan | 24 | 2001 |  NYG | 16 | 61 | 12 | 73 | 22.5 | 177.5 | 0 | 0 | 0 | 6 | 1 | 1 |
| 6 |  | M. Crosby | 23 | 2023 |  LV | 17 | 55 | 35 | 90 | 14.5 | 100 | 0 | 0 | 0 | 2 | 1 | 0 |
| 7 |  | K. Mack | 23 | 2015 | OAK | 16 | 57 | 20 | 77 | 15.0 | 89 | 0 | 0 | 0 | 2 | 0 | 0 |
| 8 |  | R. Quinn | 23 | 2013 |  STL | 16 | 50 | 7 | 57 | 19.0 | 145 | 0 | 0 | 0 | 7 | 2 | 1 |
| 9 | | J. Pierre-Paul | 23 | 2011 | NYG | 16 | 66 | 20 | 86 | 16.5 | 112 | 0 | 0 | 0 | 2 | 0 | 0 |
| 10 | | M. Strahan | 23 | 2003 | NYG | 16 | 60 | 15 | 75 | 18.5 | 126.5 | 0 | 0 | 0 | 3 | 1 | 0 |
| 11 |  | M. Garrett | 22 | 2024 |  CLE | 17 | 40 | 7 | 47 | 14.0 | 92 | 0 | 0 | 0 | 3 | 1 | 0 |
| 12 | | M. Crosby | 22 | 2022 | LV | 17 | 58 | 31 | 89 | 12.5 | 102 | 0 | 0 | 0 | 3 | 1 | 0 |
| 13 | | A. Donald | 22 | 2015 | STL | 16 | 44 | 25 | 69 | 11.0 | 59.5 | 0 | 0 | 0 | 0 | 1 | 0 |
| 14 | | J.J. Watt | 22 | 2013 | HOU | 16 | 65 | 15 | 80 | 10.5 | 70.5 | 0 | 0 | 0 | 4 | 2 | 0 |
| 15 |  | N. Bosa | 21 | 2021 |  SF | 17 | 40 | 12 | 52 | 15.5 | 122 | 0 | 0 | 0 | 4 | 0 | 0 |
| 16 | | D. Hunter | 21 | 2018 |  MIN | 16 | 51 | 21 | 72 | 14.5 | 91 | 0 | 0 | 0 | 0 | 1 | 1 |
| 17 |  | N. Suh | 21 | 2014 |  DET | 16 | 44 | 9 | 53 | 8.5 | 54.5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18 |  | J. Allen | 21 | 2011 | MIN | 16 | 48 | 18 | 66 | 22.0 | 150.5 | 1 | 14 | 0 | 4 | 4 | 0 |
| 19 | | C. Griffin | 21 | 2004 |  WAS | 15 | 56 | 14 | 70 | 6.0 | 40 | 0 | 0 | 0 | 0 | 1 | 0 |
| 20 | | A. Donald | 20 | 2019 | LAR | 16 | 29 | 19 | 48 | 12.5 | 69.5 | 0 | 0 | 0 | 2 | 1 | 0 |
| 21 | | C. Campbell | 20 | 2018 |  JAX | 16 | 53 | 19 | 72 | 10.5 | 73.5 | 0 | 0 | 0 | 1 | 1 | 0 |
| 22 | | J. Abraham | 20 | 2008 |  ATL | 16 | 37 | 1 | 38 | 16.5 | 109.5 | 0 | 0 | 0 | 4 | 0 | 0 |
| 23 | | J. Allen | 20 | 2008 | MIN | 16 | 41 | 13 | 54 | 14.5 | 102.5 | 0 | 0 | 0 | 3 | 0 | 0 |
| 24 | | J. Tuck | 20 | 2008 | NYG | 16 | 51 | 14 | 65 | 12.0 | 84.5 | 1 | 41 | 1 | 3 | 0 | 0 |
| 25 | | H. Douglas | 20 | 2002 |  PHI | 16 | 45 | 8 | 53 | 12.5 | 89 | 0 | 0 | 0 | 2 | 0 | 0 |
StatMuse has season-level data for tackles for loss going back to the 2001 season.
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