Since 2021, the Los Angeles Rams, the Arizona Cardinals and the Seattle Seahawks are tied for the most wins versus the 49ers, with 4 wins.
Interpreted as:
most regular-season wins against the 49ers since 2021| TEAM | W | GP | L | T | TD | PTS | PPG | OPP PTS | OPP PPG | 1DWN | 3DWN% | 4DWN% | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Rams | 4 | 10 | 6 | 0 | 23 | 205 | 20.5 | 245 | 24.5 | 210 | 46.2 | 72.2 |
| 2 |  | Cardinals | 4 | 10 | 6 | 0 | 26 | 224 | 22.4 | 287 | 28.7 | 202 | 41.7 | 61.1 |
| 3 |  | Seahawks | 4 | 10 | 6 | 0 | 20 | 177 | 17.7 | 224 | 22.4 | 174 | 33.6 | 50.0 |
| 4 |  | Chiefs | 2 | 2 | 0 | 0 | 10 | 72 | 36.0 | 41 | 20.5 | 46 | 60.9 | 50.0 |
| 5 |  | Vikings | 2 | 3 | 1 | 0 | 8 | 71 | 23.7 | 68 | 22.7 | 58 | 51.5 | 33.3 |
| 6 |  | Packers | 2 | 2 | 0 | 0 | 8 | 68 | 34.0 | 38 | 19.0 | 43 | 45.8 | 33.3 |
| 7 |  | Bills | 1 | 1 | 0 | 0 | 5 | 35 | 35.0 | 10 | 10.0 | 20 | 50.0 | 100.0 |
| 8 |  | Ravens | 1 | 1 | 0 | 0 | 3 | 33 | 33.0 | 19 | 19.0 | 23 | 36.4 | 100.0 |
| 9 |  | Browns | 1 | 2 | 1 | 0 | 2 | 27 | 13.5 | 43 | 21.5 | 33 | 25.0 | 20.0 |
| 10 |  | Buccaneers | 1 | 4 | 3 | 0 | 9 | 71 | 17.8 | 104 | 26.0 | 77 | 36.5 | 54.5 |
| 11 |  | Dolphins | 1 | 2 | 1 | 0 | 4 | 46 | 23.0 | 50 | 25.0 | 35 | 21.1 | 50.0 |
| 12 |  | Broncos | 1 | 1 | 0 | 0 | 1 | 11 | 11.0 | 10 | 10.0 | 14 | 31.6 | |
| 13 |  | Texans | 1 | 2 | 1 | 0 | 3 | 33 | 16.5 | 38 | 19.0 | 38 | 45.2 | 50.0 |
| 14 |  | Titans | 1 | 2 | 1 | 0 | 5 | 44 | 22.0 | 54 | 27.0 | 34 | 48.0 | 100.0 |
| 15 |  | Falcons | 1 | 3 | 2 | 0 | 6 | 51 | 17.0 | 65 | 21.7 | 50 | 50.0 | 0.0 |
| 16 |  | Bengals | 1 | 2 | 1 | 0 | 6 | 54 | 27.0 | 43 | 21.5 | 51 | 33.3 | 100.0 |
| 17 |  | Jaguars | 1 | 3 | 2 | 0 | 4 | 39 | 13.0 | 85 | 28.3 | 44 | 35.1 | 66.7 |
| 18 |  | Bears | 1 | 4 | 3 | 0 | 12 | 92 | 23.0 | 123 | 30.8 | 77 | 45.1 | 100.0 |
| 19 |  | Colts | 1 | 2 | 1 | 0 | 7 | 57 | 28.5 | 66 | 33.0 | 36 | 45.8 | 50.0 |
| 20 |  | Lions | 1 | 2 | 1 | 0 | 9 | 73 | 36.5 | 75 | 37.5 | 54 | 44.8 | 50.0 |
More Rams Stats
Team Leaders 
PASS
4,707
Stafford
RUSH
1,252
Williams
REC
1,715
Nacua
Team Rankings
PPG
30.5
1st
OPP PPG
20.4
10th
RUSH YDS/G
126.6
7th
PASS YDS/G
276.9
2nd
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
