Since 2020, the Buffalo Bills have the most wins by a team when the point differential has been 21 or above points, with 25 wins.
Interpreted as:
NFL team with most regular-season wins by 21 or more points since 2020| TEAM | W | DIFF | GP | L | T | TD | PTS | PPG | OPP PTS | OPP PPG | 1DWN | 3DWN% | 4DWN% | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 25 | 699 | 25 | 0 | 0 | 122 | 960 | 38.4 | 261 | 10.4 | 598 | 52.4 | 70.0 |
| 2 |  | Ravens | 17 | 474 | 17 | 0 | 0 | 79 | 606 | 35.6 | 132 | 7.8 | 373 | 49.7 | 53.3 |
| 3 |  | Cowboys | 15 | 464 | 15 | 0 | 0 | 82 | 648 | 43.2 | 184 | 12.3 | 352 | 54.3 | 76.5 |
| 4 |  | Saints | 13 | 362 | 13 | 0 | 0 | 56 | 459 | 35.3 | 97 | 7.5 | 277 | 46.6 | 72.7 |
| 5 |  | Buccaneers | 13 | 356 | 13 | 0 | 0 | 70 | 549 | 42.2 | 193 | 14.8 | 346 | 52.5 | 66.7 |
| 6 |  | 49ers | 13 | 333 | 13 | 0 | 0 | 62 | 482 | 37.1 | 149 | 11.5 | 304 | 54.0 | 61.5 |
| 7 |  | Patriots | 12 | 376 | 12 | 0 | 0 | 57 | 470 | 39.2 | 94 | 7.8 | 278 | 47.4 | 83.3 |
| 8 |  | Dolphins | 11 | 295 | 11 | 0 | 0 | 53 | 428 | 38.9 | 133 | 12.1 | 249 | 45.2 | 68.8 |
| 9 |  | Lions | 10 | 303 | 10 | 0 | 0 | 54 | 435 | 43.5 | 132 | 13.2 | 263 | 45.9 | 66.7 |
| 10 |  | Eagles | 10 | 279 | 10 | 0 | 0 | 46 | 362 | 36.2 | 83 | 8.3 | 232 | 44.2 | 71.4 |
| 11 |  | Seahawks | 10 | 256 | 10 | 0 | 0 | 42 | 359 | 35.9 | 103 | 10.3 | 210 | 43.9 | 60.0 |
| 12 |  | Chiefs | 10 | 272 | 10 | 0 | 0 | 50 | 391 | 39.1 | 119 | 11.9 | 261 | 54.3 | 75.0 |
| 13 |  | Rams | 9 | 245 | 9 | 0 | 0 | 43 | 335 | 37.2 | 90 | 10.0 | 220 | 37.6 | 92.3 |
| 14 |  | Jaguars | 8 | 219 | 8 | 0 | 0 | 32 | 268 | 33.5 | 49 | 6.1 | 180 | 41.4 | 69.2 |
| 15 |  | Colts | 8 | 218 | 8 | 0 | 0 | 36 | 291 | 36.4 | 73 | 9.1 | 184 | 47.1 | 90.0 |
| 16 |  | Packers | 8 | 204 | 8 | 0 | 0 | 37 | 299 | 37.4 | 95 | 11.9 | 203 | 53.6 | 58.3 |
| 17 |  | Cardinals | 7 | 181 | 7 | 0 | 0 | 33 | 263 | 37.6 | 82 | 11.7 | 170 | 53.7 | 100.0 |
| 18 |  | Chargers | 6 | 146 | 6 | 0 | 0 | 22 | 195 | 32.5 | 49 | 8.2 | 136 | 57.8 | 100.0 |
| 19 |  | Bengals | 6 | 146 | 6 | 0 | 0 | 31 | 240 | 40.0 | 94 | 15.7 | 146 | 51.3 | 85.7 |
| 20 |  | Broncos | 6 | 172 | 6 | 0 | 0 | 24 | 201 | 33.5 | 29 | 4.8 | 150 | 54.8 | 80.0 |
| 21 |  | Commanders | 6 | 152 | 6 | 0 | 0 | 27 | 224 | 37.3 | 72 | 12.0 | 146 | 58.0 | 83.3 |
| 22 |  | Steelers | 6 | 148 | 6 | 0 | 0 | 24 | 206 | 34.3 | 58 | 9.7 | 122 | 42.0 | 100.0 |
| 23 |  | Titans | 6 | 147 | 6 | 0 | 0 | 26 | 207 | 34.5 | 60 | 10.0 | 142 | 58.6 | 80.0 |
| 24 |  | Vikings | 5 | 139 | 5 | 0 | 0 | 24 | 183 | 36.6 | 44 | 8.8 | 106 | 46.6 | 100.0 |
| 25 |  | Texans | 5 | 131 | 5 | 0 | 0 | 17 | 160 | 32.0 | 29 | 5.8 | 112 | 41.9 | 71.4 |
More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |