The Pittsburgh Steelers have a record of 4-6 against the spread in the regular-season and playoffs versus the Bills since 2007.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Steelers | 9/16/2007 | 1-0 | -575 | vs | +425 | W 26-3 | -9.5 | +13.5 (Y) | 38.5 | -9.5 (U) | 2 | 24 | 420 | 223 | 68.8 | |||
| 2 | | Steelers | 11/28/2010 | 0-1 | -300 | @ | +250 | W 19-16 | -6.5 | -3.5 (N) | 43.5 | -8.5 (U) | 1 | 28 | 426 | 329 | 63.2 | |||
| 3 | | Steelers | 11/10/2013 | 1-0 | -150 | vs | +130 | W 23-10 | -3 | +10 (Y) | 43 | -10 (U) | 2 | 19 | 300 | 227 | 47.1 | |||
| 4 | | Steelers | 12/11/2016 | 1-0 | -125 | @ | +105 | W 27-20 | -2 | +5 (Y) | 46 | +1 (O) | 3 | 24 | 460 | 275 | 42.9 | 100.0 | ||
| 5 | | Steelers | 12/15/2019 | 0-1 | -120 | vs | -101 | L 10-17 | -1.5 | -8.5 (N) | 37 | -10 (U) | 1 | 15 | 229 | 261 | 38.5 | 0.0 | ||
| 6 | | Steelers | 12/13/2020 | 0-1 | +112 | @ | -132 | L 15-26 | +2 | -9 (N) | 48.5 | -7.5 (U) | 2 | 14 | 224 | 334 | 10.0 | |||
| 7 | | Steelers | 9/12/2021 | 1-0 | +229 | @ | -286 | W 23-16 | +6.5 | +13.5 (Y) | 48.5 | -9.5 (U) | 2 | 16 | 252 | 371 | 33.3 | |||
| 8 | | Steelers | 10/9/2022 | 0-1 | +611 | @ | -908 | L 3-38 | +14 | -21 (N) | 44.5 | -3.5 (U) | 0 | 23 | 364 | 552 | 33.3 | 0.0 | ||
| 9 | | Steelers | 1/15/2024 | 0-1 | +383 | @ | -514 | L 17-31 | +10 | -4 (N) | 39.5 | +8.5 (O) | 2 | 22 | 324 | 368 | 45.5 | 0.0 | ||
| 10 | | Steelers | 11/30/2025 | 0-1 | +145 | vs | -175 | L 7-26 | +3 | -16 (N) | 44.5 | -11.5 (U) | 1 | 10 | 166 | 372 | 33.3 | 0.0 | ||
| Average | 4.0 | 1.6 | 19.5 | 316.5 | 331.2 | 44.1 | 2.9 | |||||||||||||
| Total | 4-6 | 16 | 195 | 3,165 | 3,312 | 44.1 | 14.3 |
StatMuse has team, game-level data for spread records going back to the 1979 season.
More Steelers Stats
Team Leaders 
PASS
3,322
Rodgers
RUSH
958
Warren
REC
850
Metcalf
Team Rankings
PPG
23.4
15th
OPP PPG
22.8
17th
RUSH YDS/G
103.3
26th
PASS YDS/G
213.6
22nd
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
