which afc qb has the most passing td in a season against the nfc

Peyton Manning has the most passing touchdowns by an AFC quarterback against the NFC in a season, with 19 touchdowns in 2004.

	NAME	TD	SEASON	TM	GP	CMP	ATT	PCT	YDS	AVG	YDS/G	INT	RTG	TD%	INT%	SCK	SCKY
1	Peyton Manning P. Manning	19	2004	IND	4	91	125	72.8	1,108	8.9	277.0	1	135.9	15.2	0.8	1	4
2	Lamar Jackson L. Jackson	14	2024	BAL	5	93	124	75.0	1,313	10.6	262.6	1	143.0	11.3	0.8	9	73
3	Justin Herbert J. Herbert	14	2023	LAC	5	141	200	70.5	1,513	7.6	302.6	2	111.5	7.0	1.0	4	33
4	Patrick Mahomes P. Mahomes	14	2022	KC	5	121	180	67.2	1,576	8.8	315.2	3	113.6	7.8	1.7	5	31
5	Ben Roethlisberger B. Roethlisberger	14	2018	PIT	4	104	142	73.2	1,311	9.2	327.8	2	128.6	9.9	1.4	7	40
6	Patrick Mahomes P. Mahomes	14	2018	KC	4	101	152	66.4	1,314	8.6	328.5	3	116.0	9.2	2.0	11	82
7	Peyton Manning P. Manning	14	2013	DEN	4	121	163	74.2	1,402	8.6	350.5	4	118.2	8.6	2.5	3	21
8	Peyton Manning P. Manning	14	2003	IND	4	102	136	75.0	1,283	9.4	320.8	2	132.1	10.3	1.5	3	23
9	Josh Allen J. Allen	13	2021	BUF	5	121	185	65.4	1,256	6.8	251.2	7	92.5	7.0	3.8	9	44
10	Josh Allen J. Allen	13	2020	BUF	4	119	160	74.4	1,385	8.7	346.3	3	119.4	8.1	1.9	12	73
11	Dan Marino D. Marino	13	1985	MIA	4	94	154	61.0	1,164	7.6	291.0	5	99.1	8.4	3.2	4	33
12	Dan Marino D. Marino	13	1984	MIA	4	88	138	63.8	1,326	9.6	331.5	3	117.6	9.4	2.2	3	33
13	Bo Nix B. Nix	12	2025	DEN	5	122	197	61.9	1,391	7.1	278.2	2	99.2	6.1	1.0	5	34
14	Patrick Mahomes P. Mahomes	12	2025	KC	5	108	164	65.9	1,228	7.5	245.6	3	104.9	7.3	1.8	13	84
15	Joe Burrow J. Burrow	12	2022	CIN	5	135	182	74.2	1,386	7.6	277.2	1	115.3	6.6	0.5	15	104
16	Patrick Mahomes P. Mahomes	12	2020	KC	4	117	185	63.2	1,366	7.4	341.5	1	104.9	6.5	0.5	8	39
17	Andrew Luck A. Luck	12	2014	IND	4	79	129	61.2	1,005	7.8	251.3	4	103.7	9.3	3.1	2	18
18	Carson Palmer C. Palmer	12	2005	CIN	4	93	136	68.4	1,017	7.5	254.3	4	107.4	8.8	2.9	5	32
19	Peyton Manning P. Manning	12	2000	IND	4	98	152	64.5	1,167	7.7	291.8	5	100.4	7.9	3.3	7	55
20	Boomer Esiason B. Esiason	12	1989	CIN	4	96	157	61.1	1,147	7.3	286.8	4	98.3	7.6	2.5	11	95
21	Boomer Esiason B. Esiason	12	1988	CIN	4	63	106	59.4	1,026	9.7	256.5	2	121.8	11.3	1.9	6	43
22	Drake Maye D. Maye	11	2025	NE	5	91	134	67.9	1,275	9.5	255.0	2	119.5	8.2	1.5	12	46
23	Josh Allen J. Allen	11	2024	BUF	5	100	145	69.0	1,367	9.4	273.4	1	121.3	7.6	0.7	3	12
24	Joe Burrow J. Burrow	11	2021	CIN	5	109	158	69.0	1,368	8.7	273.6	6	103.0	7.0	3.8	20	148
25	Ben Roethlisberger B. Roethlisberger	11	2020	PIT	4	110	161	68.3	1,079	6.7	269.8	1	107.1	6.8	0.6	3	29

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Patriots - y	14	3	0	.824
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Jets - e	3	14	0	.176
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Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
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Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
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Peyton Manning has the most passing touchdowns by an AFC quarterback against the NFC in a season, with 19 touchdowns in 2004.

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