22 quarterbacks are tied for the highest passer rating by a quarterback in a game, with a 158.3 rating. The first three are Tom Brady on December 26 and on November 25, 2010, Lamar Jackson on November 10, 2019 and on September 8, 2019 and Aaron Rodgers on October 20, 2019.

which qb has the best qb rating in a game
Interpreted as:
Which qb has the best qb rating in a regular-season game?

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