The San Francisco 49ers are 23-14 against the spread against the NFC on the road since January 22, 2021.

	TEAM	DATE	ATS	TM			OPP		RESULT	SPREAD	ATS DIFF	O/U	O/U DIFF	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	49ers	9/12/2021	1-0	SF	-371	@	DET	+285	W 41-33	-7.5	+0.5 (Y)	45	+29 (O)	5	21	442	430	33.3
2	49ers	9/19/2021	1-0	SF	-150	@	PHI	+127	W 17-11	-3	+3 (Y)	49	-21 (U)	2	23	306	328	42.9	100.0
3	49ers	10/10/2021	0-1	SF	+208	@	ARI	-257	L 10-17	+5.5	-1.5 (N)	48.5	-21.5 (U)	1	19	338	304	27.3	20.0
4	49ers	10/31/2021	1-0	SF	-210	@	CHI	+172	W 33-22	-4.5	+6.5 (Y)	40	+15 (O)	3	21	467	324	40.0	100.0
5	49ers	12/5/2021	0-1	SF	-143	@	SEA	+122	L 23-30	-2.5	-9.5 (N)	44.5	+8.5 (O)	3	17	365	327	30.0	50.0
6	49ers	1/9/2022	1-0	SF	+151	@	LAR	-178	W 27-24	+3.5	+6.5 (Y)	46.5	+4.5 (O)	3	23	449	265	64.3
7	49ers	1/16/2022	1-0	SF	+153	@	DAL	-181	W 23-17	+3.5	+9.5 (Y)	51	-11 (U)	2	21	341	307	46.2
8	49ers	1/22/2022	1-0	SF	+208	@	GB	-254	W 13-10	+5.5	+8.5 (Y)	47	-24 (U)	1	12	212	263	36.4	0.0
9	49ers	1/30/2022	1-0	SF	+155	@	LAR	-183	L 17-20	+3.5	+0.5 (Y)	45.5	-8.5 (U)	2	16	282	396	33.3
10	49ers	9/11/2022	0-1	SF	-285	@	CHI	+230	L 10-19	-6.5	-15.5 (N)	38	-9 (U)	1	17	331	204	47.1	0.0
11	49ers	10/9/2022	1-0	SF	-261	@	CAR	+211	W 37-15	-6	+16 (Y)	39.5	+12.5 (O)	5	22	397	308	58.3
12	49ers	10/16/2022	0-1	SF	-192	@	ATL	+161	L 14-28	-3.5	-17.5 (N)	46	-4 (U)	2	21	346	289	37.5	0.0
13	49ers	10/30/2022	1-0	SF	-107	@	LAR	-113	W 31-14	-1.5	+15.5 (Y)	42	+3 (O)	4	22	368	223	55.6
14	49ers	11/21/2022	1-0	SF	-442	@	ARI	+341	W 38-10	-9.5	+18.5 (Y)	43	+5 (O)	5	21	387	314	54.5
15	49ers	12/15/2022	1-0	SF	-181	@	SEA	+152	W 21-13	-3	+5 (Y)	42.5	-8.5 (U)	3	15	381	277	46.2
16	49ers	1/29/2023	0-1	SF	+131	@	PHI	-155	L 7-31	+3	-21 (N)	44.5	-6.5 (U)	1	11	164	269	25.0	0.0
17	49ers	9/17/2023	0-1	SF	-343	@	LAR	+273	W 30-23	-7.5	-0.5 (N)	45	+8 (O)	3	21	365	386	22.2
18	49ers	10/23/2023	0-1	SF	-315	@	MIN	+251	L 17-22	-7	-12 (N)	44	-5 (U)	2	19	325	452	55.6	100.0
19	49ers	11/23/2023	1-0	SF	-334	@	SEA	+260	W 31-13	-7	+11 (Y)	43	+1 (O)	4	23	377	220	45.5
20	49ers	12/3/2023	1-0	SF	-158	@	PHI	+134	W 42-19	-3	+20 (Y)	46.5	+14.5 (O)	6	24	456	333	72.7	100.0
21	49ers	12/17/2023	1-0	SF	-771	@	ARI	+529	W 45-29	-12.5	+3.5 (Y)	48	+26 (O)	6	24	406	436	57.1
22	49ers	12/31/2023	1-0	SF	-967	@	WAS	+633	W 27-10	-14	+3 (Y)	48.5	-11.5 (U)	3	28	408	225	44.4	0.0
23	49ers	9/15/2024	0-1	SF	-213	@	MIN	+176	L 17-23	-4	-10 (N)	46.5	-6.5 (U)	2	24	396	403	20.0	33.3
24	49ers	9/22/2024	0-1	SF	-270	@	LAR	+220	L 24-27	-6	-9 (N)	44.5	+6.5 (O)	3	25	425	296	54.5	100.0
25	49ers	10/10/2024	1-0	SF	-199	@	SEA	+165	W 36-24	-3.5	+8.5 (Y)	49	+11 (O)	4	21	483	358	41.7
	Average		1.7											2.8	20.8	363.3	321.0	45.0	0.0
	Total		23-14											105	770	13,442	11,877	45.0	40.5

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More 49ers Stats

Team Leaders

PASS

205

Purdy

RUSH

68

McCaffrey

REC

50

Robinson

Team Rankings

PPG

27.0

1st

OPP PPG

7.0

1st

RUSH YDS/G

174.0

1st

PASS YDS/G

205.0

1st

2026 Division Standings

TEAM	W	L	PCT
49ers	1	0	1.000
Seahawks	1	0	1.000
Cardinals	0	0
Rams	0	1	.000

Schedule

DATE	MATCHUP			TIME (ET)
Sun 9/20	MIA	@	SF	4:25 PM
Sun 9/27	ARI	@	SF	4:05 PM
Sun 10/4	DEN	@	SF	4:25 PM
Sun 10/11	SF	@	SEA	4:25 PM
Mon 10/19	WAS	@	SF	8:15 PM

Last Game

49ers

1 - 0

Final

Rams

0 - 1

Thu 10 Sep 2026

NFL 2026 Leaders

Pass Yards Leaders

205

Purdy

187

Lock

178

Maye

Rush Yards Leaders

68

McCaffrey

65

Black

54

Corum

Rec Yards Leaders

122

Smith-Njigba

74

Nacua

51

Hollins

Pass TD Leaders

3

Purdy

1

Maye

1

Lock

Rush TD Leaders

1

Williams

Rec TD Leaders

1

Smith-Njigba

1

Samuel

1

Robinson

QB Rating Leaders

113.3

Lock

105.6

Purdy

61.3

Stafford

Sack Leaders

1.0

Jacas

1.0

Thomas

1.0

Hall

NFL 2026 Rankings

PPG Rankings

27.0

13.0

10.0

7.0

Opp PPG Rankings

7.0

10.0

13.0

27.0

Total Yards Rankings

379.0

290.0

285.0

277.0

Rush Yards Rankings

174.0

122.0

109.0

97.0

Pass Yards Rankings

205.0

200.0

178.0

168.0

Sack Leaders

3.0

2.0

NFL Fantasy 2026

Fantasy RB Rankings

12.5

Williams

9.5

Stevenson

8.8

McCaffrey

Fantasy WR Rankings

18.2

Smith-Njigba

12

Samuel

11

Robinson

Fantasy TE Rankings

6.2

Raridon

2.6

Henry

1.9

Farrell

Fantasy K Rankings

11

Pineiro

7

Myers

6

Borregales

NFL 2026 Betting

Best Record ATS

1-0

0-0-1

Worst Record ATS

0-1

0-0-1

1-0

NFL 2026 Standings

NFC East	W	L	T	PCT
Giants	0	0	0
Eagles	0	0	0
Cowboys	0	0	0
Commanders	0	0	0
NFC North	W	L	T	PCT
Bears	0	0	0
Lions	0	0	0
Vikings	0	0	0
Packers	0	0	0
NFC South	W	L	T	PCT
Buccaneers	0	0	0
Saints	0	0	0
Panthers	0	0	0
Falcons	0	0	0
NFC West	W	L	T	PCT
49ers	1	0	0	1.000
Seahawks	1	0	0	1.000
Cardinals	0	0	0
Rams	0	1	0	.000

AFC East	W	L	T	PCT
Bills	0	0	0
Dolphins	0	0	0
Jets	0	0	0
Patriots	0	1	0	.000
AFC North	W	L	T	PCT
Ravens	0	0	0
Bengals	0	0	0
Browns	0	0	0
Steelers	0	0	0
AFC South	W	L	T	PCT
Colts	0	0	0
Texans	0	0	0
Titans	0	0	0
Jaguars	0	0	0
AFC West	W	L	T	PCT
Raiders	0	0	0
Chiefs	0	0	0
Chargers	0	0	0
Broncos	0	0	0