The San Francisco 49ers have a record of 31-22 against the spread as favorites against the NFC since January 26, 2020.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 9/13/2020 | 0-1 |  SF | -312 | vs |  ARI | +245 | L 20-24 | -6.5 | -10.5 (N) | 48 | -4 (U) | 2 | 18 | 366 | 404 | 18.2 | 0.0 |
| 2 | | 49ers | 9/27/2020 | 1-0 | SF | -161 | @ |  NYG | +136 | W 36-9 | -3 | +24 (Y) | 43.5 | +1.5 (O) | 4 | 29 | 420 | 231 | 66.7 | |
| 3 | | 49ers | 10/4/2020 | 0-1 | SF | -351 | vs |  PHI | +283 | L 20-25 | -8.5 | -13.5 (N) | 45.5 | -0.5 (U) | 3 | 25 | 417 | 267 | 45.5 | 0.0 |
| 4 | | 49ers | 12/13/2020 | 0-1 | SF | -150 | vs |  WAS | +127 | L 15-23 | -3 | -11 (N) | 43 | -5 (U) | 2 | 21 | 344 | 193 | 26.7 | 0.0 |
| 5 | | 49ers | 12/20/2020 | 0-1 | SF | -194 | @ |  DAL | +163 | L 33-41 | -3.5 | -11.5 (N) | 45.5 | +28.5 (O) | 4 | 28 | 458 | 291 | 40.0 | 100.0 |
| 6 | | 49ers | 9/12/2021 | 1-0 | SF | -371 | @ |  DET | +285 | W 41-33 | -7.5 | +0.5 (Y) | 45 | +29 (O) | 5 | 21 | 442 | 430 | 33.3 | |
| 7 | | 49ers | 9/19/2021 | 1-0 | SF | -150 | @ | PHI | +127 | W 17-11 | -3 | +3 (Y) | 49 | -21 (U) | 2 | 23 | 306 | 328 | 42.9 | 100.0 |
| 8 | | 49ers | 9/26/2021 | 0-1 | SF | -174 | vs |  GB | +148 | L 28-30 | -3 | -5 (N) | 50.5 | +7.5 (O) | 4 | 26 | 298 | 353 | 63.6 | |
| 9 | | 49ers | 10/3/2021 | 0-1 | SF | -137 | vs |  SEA | +115 | L 21-28 | -2.5 | -9.5 (N) | 52 | -3 (U) | 3 | 23 | 457 | 234 | 14.3 | 75.0 |
| 10 | | 49ers | 10/31/2021 | 1-0 | SF | -210 | @ |  CHI | +172 | W 33-22 | -4.5 | +6.5 (Y) | 40 | +15 (O) | 3 | 21 | 467 | 324 | 40.0 | 100.0 |
| 11 | | 49ers | 11/7/2021 | 0-1 | SF | -247 | vs | ARI | +199 | L 17-31 | -5.5 | -19.5 (N) | 44.5 | +3.5 (O) | 2 | 22 | 337 | 437 | 40.0 | |
| 12 | | 49ers | 11/28/2021 | 1-0 | SF | -200 | vs |  MIN | +168 | W 34-26 | -4 | +4 (Y) | 49 | +11 (O) | 4 | 23 | 423 | 323 | 41.7 | |
| 13 | | 49ers | 12/5/2021 | 0-1 | SF | -143 | @ | SEA | +122 | L 23-30 | -2.5 | -9.5 (N) | 44.5 | +8.5 (O) | 3 | 17 | 365 | 327 | 30.0 | 50.0 |
| 14 | | 49ers | 12/19/2021 | 1-0 | SF | -408 | vs |  ATL | +311 | W 31-13 | -9 | +9 (Y) | 47.5 | -3.5 (U) | 4 | 23 | 397 | 275 | 54.5 | |
| 15 | | 49ers | 9/11/2022 | 0-1 | SF | -285 | @ | CHI | +230 | L 10-19 | -6.5 | -15.5 (N) | 38 | -9 (U) | 1 | 17 | 331 | 204 | 47.1 | 0.0 |
| 16 | | 49ers | 9/18/2022 | 1-0 | SF | -394 | vs | SEA | +306 | W 27-7 | -8.5 | +11.5 (Y) | 39.5 | -5.5 (U) | 3 | 25 | 373 | 216 | 40.0 | 66.7 |
| 17 | | 49ers | 10/3/2022 | 1-0 | SF | -125 | vs |  LAR | +105 | W 24-9 | -2 | +13 (Y) | 42 | -9 (U) | 3 | 13 | 327 | 257 | 41.7 | 0.0 |
| 18 | | 49ers | 10/9/2022 | 1-0 | SF | -261 | @ |  CAR | +211 | W 37-15 | -6 | +16 (Y) | 39.5 | +12.5 (O) | 5 | 22 | 397 | 308 | 58.3 | |
| 19 | | 49ers | 10/16/2022 | 0-1 | SF | -192 | @ | ATL | +161 | L 14-28 | -3.5 | -17.5 (N) | 46 | -4 (U) | 2 | 21 | 346 | 289 | 37.5 | 0.0 |
| 20 | | 49ers | 10/30/2022 | 1-0 | SF | -107 | @ | LAR | -113 | W 31-14 | -1.5 | +15.5 (Y) | 42 | +3 (O) | 4 | 22 | 368 | 223 | 55.6 | |
| 21 | | 49ers | 11/21/2022 | 1-0 | SF | -442 | @ | ARI | +341 | W 38-10 | -9.5 | +18.5 (Y) | 43 | +5 (O) | 5 | 21 | 387 | 314 | 54.5 | |
| 22 | | 49ers | 11/27/2022 | 1-0 | SF | -426 | vs |  NO | +325 | W 13-0 | -8.5 | +4.5 (Y) | 43.5 | -30.5 (U) | 1 | 21 | 317 | 260 | 38.5 | 50.0 |
| 23 | | 49ers | 12/11/2022 | 1-0 | SF | -182 | vs |  TB | +152 | W 35-7 | -3.5 | +24.5 (Y) | 38.5 | +3.5 (O) | 5 | 24 | 404 | 322 | 44.4 | 50.0 |
| 24 | | 49ers | 12/15/2022 | 1-0 | SF | -181 | @ | SEA | +152 | W 21-13 | -3 | +5 (Y) | 42.5 | -8.5 (U) | 3 | 15 | 381 | 277 | 46.2 | |
| 25 | | 49ers | 12/24/2022 | 1-0 | SF | -299 | vs |  WAS | +240 | W 37-20 | -6.5 | +10.5 (Y) | 37 | +20 (O) | 4 | 14 | 371 | 349 | 36.4 | 50.0 |
| Average | 1.1 | 3.3 | 22.0 | 381.3 | 299.4 | 45.1 | 1.6 | |||||||||||||
| Total | 31-22 | 174 | 1,164 | 20,209 | 15,869 | 45.1 | 51.1 | |||||||||||||
StatMuse has team, game-level data for spread records going back to the 1979 season.
More 49ers Stats
Team Rankings
PPG
23.7
14th
OPP PPG
22.9
16th
RUSH YDS/G
94.8
28th
PASS YDS/G
267.0
3rd
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