The San Francisco 49ers have a 15-13 record in the regular-season and playoffs versus the Saints since September 17, 1995.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 10/29/1995 | 0-1 |  SF | vs |  NO | L 7-11 | .000 | 1 | 19 | 286 | 252 | 50.0 | 100.0 |
| 2 | | 49ers | 9/1/1996 | 1-0 | SF | vs | NO | W 27-11 | 1.000 | 3 | 23 | 338 | 231 | 31.3 | 100.0 |
| 3 | | 49ers | 11/3/1996 | 1-0 | SF | @ | NO | W 24-17 | 1.000 | 2 | 17 | 306 | 293 | 23.1 | 100.0 |
| 4 | | 49ers | 9/14/1997 | 1-0 | SF | vs | NO | W 33-7 | 1.000 | 3 | 17 | 304 | 260 | 37.5 | 100.0 |
| 5 | | 49ers | 10/26/1997 | 1-0 | SF | @ | NO | W 23-0 | 1.000 | 2 | 21 | 347 | 142 | 43.8 | |
| 6 | | 49ers | 10/11/1998 | 1-0 | SF | @ | NO | W 31-0 | 1.000 | 3 | 30 | 459 | 167 | 46.7 | 0.0 |
| 7 | | 49ers | 11/22/1998 | 1-0 | SF | vs | NO | W 31-20 | 1.000 | 4 | 23 | 443 | 401 | 66.7 | |
| 8 | | 49ers | 9/19/1999 | 1-0 | SF | vs | NO | W 28-21 | 1.000 | 4 | 21 | 311 | 324 | 18.2 | 50.0 |
| 9 | | 49ers | 11/14/1999 | 0-1 | SF | @ | NO | L 6-24 | .000 | 0 | 16 | 234 | 365 | 27.3 | 100.0 |
| 10 | | 49ers | 11/5/2000 | 0-1 | SF | @ | NO | L 15-31 | .000 | 2 | 19 | 346 | 360 | 36.4 | 100.0 |
| 11 | | 49ers | 12/10/2000 | 0-1 | SF | vs | NO | L 27-31 | .000 | 4 | 21 | 398 | 388 | 45.5 | 0.0 |
| 12 | | 49ers | 11/11/2001 | 1-0 | SF | vs | NO | W 28-27 | 1.000 | 4 | 21 | 415 | 488 | 41.7 | |
| 13 | | 49ers | 1/6/2002 | 1-0 | SF | @ | NO | W 38-0 | 1.000 | 5 | 22 | 407 | 126 | 35.7 | 50.0 |
| 14 | | 49ers | 10/20/2002 | 0-1 | SF | @ | NO | L 27-35 | .000 | 3 | 26 | 418 | 422 | 75.0 | |
| 15 | | 49ers | 9/19/2004 | 0-1 | SF | @ | NO | L 27-30 | .000 | 3 | 22 | 370 | 302 | 38.5 | |
| 16 | | 49ers | 12/3/2006 | 0-1 | SF | @ | NO | L 10-34 | .000 | 1 | 10 | 202 | 375 | 27.3 | |
| 17 | | 49ers | 10/28/2007 | 0-1 | SF | vs | NO | L 10-31 | .000 | 1 | 15 | 260 | 438 | 52.6 | 0.0 |
| 18 | | 49ers | 9/28/2008 | 0-1 | SF | @ | NO | L 17-31 | .000 | 1 | 20 | 312 | 467 | 30.0 | 100.0 |
| 19 | | 49ers | 9/20/2010 | 0-1 | SF | vs | NO | L 22-25 | .000 | 3 | 24 | 417 | 287 | 55.6 | |
| 20 | | 49ers | 1/14/2012 | 1-0 | SF | vs | NO | W 36-32 | 1.000 | 4 | 17 | 407 | 472 | 26.7 | |
| 21 | | 49ers | 11/25/2012 | 1-0 | SF | @ | NO | W 31-21 | 1.000 | 4 | 18 | 375 | 290 | 46.2 | |
| 22 | | 49ers | 11/17/2013 | 0-1 | SF | @ | NO | L 20-23 | .000 | 2 | 12 | 196 | 387 | 40.0 | |
| 23 | | 49ers | 11/9/2014 | 1-0 | SF | @ | NO | W 27-24 | 1.000 | 3 | 21 | 330 | 423 | 40.0 | 100.0 |
| 24 | | 49ers | 11/6/2016 | 0-1 | SF | vs | NO | L 23-41 | .000 | 2 | 19 | 486 | 571 | 22.2 | 0.0 |
| 25 | | 49ers | 12/8/2019 | 1-0 | SF | @ | NO | W 48-46 | 1.000 | 6 | 25 | 516 | 465 | 50.0 | 100.0 |
| Average | .536 | 2.7 | 20.1 | 350.9 | 339.3 | 41.4 | 3.4 | ||||||||
| Total | 15-13 | .536 | 75 | 564 | 9,825 | 9,500 | 41.4 | 58.3 | |||||||
More 49ers Stats
Team Rankings
PPG
21.2
21st
OPP PPG
19.6
8th
RUSH YDS/G
85.2
29th
PASS YDS/G
298.2
2nd
Rams 
Cardinals 
HOU 
NYG 
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 0 | 0 | 1.000 |
 Commanders | 2 | 2 | 0 | .500 |
| NFC North | W | L | T | PCT |
 Lions | 3 | 1 | 0 | .750 |
 Packers | 2 | 1 | 1 | .625 |
| NFC South | W | L | T | PCT |
 Buccaneers | 3 | 1 | 0 | .750 |
 Falcons | 2 | 2 | 0 | .500 |
| NFC West | W | L | T | PCT |
| 49ers | 4 | 1 | 0 | .800 |
 Seahawks | 3 | 1 | 0 | .750 |
Bills 
Patriots 
Steelers 
Bengals 
Colts 
Jaguars 
Chargers 
Chiefs 
DAL 
NYJ 
LV 
MIN 
CLE 
BAL 
DEN 
