The Buffalo Bills have a record of 55-88 against the AFC in the regular-season and playoffs on the road since 2002.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 9/22/2002 | 0-1 |  BUF | @ |  DEN | L 23-28 | .000 | 3 | 17 | 291 | 342 | 42.9 | |
| 2 | | Bills | 10/13/2002 | 1-0 | BUF | @ |  HOU | W 31-24 | 1.000 | 4 | 25 | 403 | 338 | 42.9 | |
| 3 | | Bills | 10/20/2002 | 1-0 | BUF | @ |  MIA | W 23-10 | 1.000 | 2 | 15 | 294 | 287 | 23.1 | 0.0 |
| 4 | | Bills | 11/17/2002 | 0-1 | BUF | @ |  KC | L 16-17 | .000 | 1 | 21 | 344 | 320 | 53.8 | |
| 5 | | Bills | 11/24/2002 | 0-1 | BUF | @ |  NYJ | L 13-31 | .000 | 1 | 17 | 258 | 325 | 40.0 | 50.0 |
| 6 | | Bills | 12/8/2002 | 0-1 | BUF | @ |  NE | L 17-27 | .000 | 2 | 24 | 390 | 275 | 71.4 | |
| 7 | | Bills | 9/14/2003 | 1-0 | BUF | @ |  JAX | W 38-17 | 1.000 | 5 | 20 | 371 | 287 | 57.1 | 50.0 |
| 8 | | Bills | 9/21/2003 | 0-1 | BUF | @ | MIA | L 7-17 | .000 | 1 | 8 | 118 | 313 | 11.1 | |
| 9 | | Bills | 10/12/2003 | 0-1 | BUF | @ | NYJ | L 3-30 | .000 | 0 | 15 | 193 | 233 | 33.3 | 25.0 |
| 10 | | Bills | 10/26/2003 | 0-1 | BUF | @ | KC | L 5-38 | .000 | 0 | 15 | 266 | 375 | 27.3 | 0.0 |
| 11 | | Bills | 12/14/2003 | 0-1 | BUF | @ |  TEN | L 26-28 | .000 | 3 | 13 | 241 | 349 | 16.7 | 100.0 |
| 12 | | Bills | 12/27/2003 | 0-1 | BUF | @ | NE | L 0-31 | .000 | 0 | 16 | 256 | 321 | 47.1 | 33.3 |
| 13 | | Bills | 9/19/2004 | 0-1 | BUF | @ |  OAK | L 10-13 | .000 | 1 | 14 | 243 | 273 | 30.8 | 66.7 |
| 14 | | Bills | 10/10/2004 | 0-1 | BUF | @ | NYJ | L 14-16 | .000 | 2 | 17 | 252 | 383 | 38.5 | 0.0 |
| 15 | | Bills | 10/24/2004 | 0-1 | BUF | @ |  BAL | L 6-20 | .000 | 0 | 15 | 270 | 160 | 37.5 | 0.0 |
| 16 | | Bills | 11/14/2004 | 0-1 | BUF | @ | NE | L 6-29 | .000 | 1 | 8 | 125 | 428 | 0.0 | 0.0 |
| 17 | | Bills | 12/5/2004 | 1-0 | BUF | @ | MIA | W 42-32 | 1.000 | 6 | 16 | 362 | 403 | 23.1 | |
| 18 | | Bills | 12/19/2004 | 1-0 | BUF | @ |  CIN | W 33-17 | 1.000 | 3 | 13 | 212 | 275 | 23.1 | 0.0 |
| 19 | | Bills | 10/23/2005 | 0-1 | BUF | @ | OAK | L 17-38 | .000 | 2 | 15 | 210 | 416 | 30.0 | 0.0 |
| 20 | | Bills | 10/30/2005 | 0-1 | BUF | @ | NE | L 16-21 | .000 | 1 | 24 | 394 | 273 | 50.0 | 0.0 |
| 21 | | Bills | 11/20/2005 | 0-1 | BUF | @ |  SD | L 10-48 | .000 | 1 | 12 | 202 | 478 | 23.1 | 50.0 |
| 22 | | Bills | 12/4/2005 | 0-1 | BUF | @ | MIA | L 23-24 | .000 | 3 | 16 | 294 | 434 | 42.9 | |
| 23 | | Bills | 12/24/2005 | 1-0 | BUF | @ | CIN | W 37-27 | 1.000 | 4 | 19 | 355 | 374 | 45.5 | 0.0 |
| 24 | | Bills | 1/1/2006 | 0-1 | BUF | @ | NYJ | L 26-30 | .000 | 2 | 21 | 331 | 207 | 57.1 | 0.0 |
| 25 | | Bills | 9/10/2006 | 0-1 | BUF | @ | NE | L 17-19 | .000 | 2 | 12 | 240 | 319 | 27.3 | 0.0 |
| Average | .385 | 2.2 | 18.5 | 320.1 | 336.0 | 38.8 | 0.5 | ||||||||
| Total | 55-88 | .385 | 321 | 2,651 | 45,773 | 48,046 | 38.8 | 48.5 | |||||||
More Bills Stats
Team Rankings
PPG
33.3
2nd
OPP PPG
22.5
17th
RUSH YDS/G
163.5
1st
PASS YDS/G
249.0
7th
Jets 
CAR 
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 0 | 0 | 1.000 |
 Commanders | 2 | 2 | 0 | .500 |
| NFC North | W | L | T | PCT |
 Lions | 3 | 1 | 0 | .750 |
 Packers | 2 | 1 | 1 | .625 |
| NFC South | W | L | T | PCT |
 Buccaneers | 3 | 1 | 0 | .750 |
 Falcons | 2 | 2 | 0 | .500 |
| NFC West | W | L | T | PCT |
 49ers | 4 | 1 | 0 | .800 |
 Seahawks | 3 | 1 | 0 | .750 |
Steelers 
Colts 
DAL 
MIN 
CLE 
NYG 
NO 
