The Buffalo Bills had a point differential of 232 points in the regular-season and playoffs between December 28, 2021 and September 17, 2023.
| TEAM | DATE | DIFF | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 1/2/2022 | 14 | vs | W 29-15 | 4 | 28 | 351 | 265 | 58.3 | 100.0 | ||
| 2 | | Bills | 1/9/2022 | 17 | vs | W 27-10 | 3 | 25 | 424 | 63 | 44.4 | 0.0 | ||
| 3 | | Bills | 1/15/2022 | 30 | vs | W 47-17 | 7 | 29 | 482 | 305 | 85.7 | |||
| 4 | | Bills | 1/23/2022 | -6 | @ | L 36-42 | 5 | 23 | 422 | 552 | 42.9 | 100.0 | ||
| 5 | | Bills | 9/8/2022 | 21 | @ | W 31-10 | 4 | 23 | 413 | 243 | 90.0 | |||
| 6 | | Bills | 9/19/2022 | 34 | vs | W 41-7 | 5 | 23 | 414 | 187 | 38.5 | 66.7 | ||
| 7 | | Bills | 9/25/2022 | -2 | @ | L 19-21 | 2 | 31 | 497 | 212 | 61.1 | 66.7 | ||
| 8 | | Bills | 10/2/2022 | 3 | @ | W 23-20 | 2 | 22 | 326 | 296 | 36.4 | 100.0 | ||
| 9 | | Bills | 10/9/2022 | 35 | vs | W 38-3 | 5 | 21 | 552 | 364 | 55.6 | |||
| 10 | | Bills | 10/16/2022 | 4 | @ | W 24-20 | 3 | 26 | 443 | 387 | 36.4 | 33.3 | ||
| 11 | | Bills | 10/30/2022 | 10 | vs | W 27-17 | 3 | 20 | 369 | 398 | 28.6 | |||
| 12 | | Bills | 11/6/2022 | -3 | @ | L 17-20 | 2 | 19 | 317 | 310 | 61.5 | 0.0 | ||
| 13 | | Bills | 11/13/2022 | -3 | vs | L 30-33 | 3 | 29 | 486 | 481 | 53.8 | 0.0 | ||
| 14 | | Bills | 11/20/2022 | 8 | vs | W 31-23 | 2 | 22 | 357 | 396 | 27.3 | |||
| 15 | | Bills | 11/24/2022 | 3 | @ | W 28-25 | 3 | 28 | 401 | 326 | 58.3 | |||
| 16 | | Bills | 12/1/2022 | 14 | @ | W 24-10 | 3 | 22 | 355 | 242 | 60.0 | |||
| 17 | | Bills | 12/11/2022 | 8 | vs | W 20-12 | 2 | 14 | 232 | 309 | 15.4 | |||
| 18 | | Bills | 12/17/2022 | 3 | vs | W 32-29 | 4 | 29 | 446 | 405 | 57.1 | |||
| 19 | | Bills | 12/24/2022 | 22 | @ | W 35-13 | 5 | 20 | 426 | 209 | 54.5 | 100.0 | ||
| 20 | | Bills | 1/8/2023 | 12 | vs | W 35-23 | 5 | 18 | 327 | 341 | 58.3 | |||
| 21 | | Bills | 1/15/2023 | 3 | vs | W 34-31 | 4 | 25 | 423 | 231 | 56.3 | 0.0 | ||
| 22 | | Bills | 1/22/2023 | -17 | vs | L 10-27 | 1 | 19 | 325 | 412 | 41.7 | 50.0 | ||
| 23 | | Bills | 9/11/2023 | -6 | @ | L 16-22 | 1 | 19 | 314 | 289 | 38.5 | |||
| 24 | | Bills | 9/17/2023 | 28 | vs | W 38-10 | 5 | 29 | 450 | 240 | 53.8 | 75.0 | ||
| Average | 9.7 | 3.5 | 23.5 | 398.0 | 311.0 | 50.3 | 4.7 | |||||||
| Total | 232 | 83 | 564 | 9,552 | 7,463 | 50.3 | 61.5 |
NYJ
CHIMore Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
