largest point differential 49ers lose all-time

The San Francisco 49ers had their highest point differential in a loss 22 times, with a -1-point differential.

Interpreted as:

largest point differential in a regular-season game 49ers lose all-time

		TEAM	DIFF	L	DATE	TM		OPP	RESULT	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1		49ers	-1	1	10/6/2024	SF	vs	ARI	L 23-24	2	22	384	358	54.5	0.0
2		49ers	-1	1	1/7/2024	SF	vs	LAR	L 20-21	3	20	300	258	50.0	100.0
3		49ers	-1	1	9/25/2022	SF	@	DEN	L 10-11	1	13	267	261	10.0
4		49ers	-1	1	11/10/2013	SF	vs	CAR	L 9-10	0	10	151	250	15.4
5		49ers	-1	1	12/18/2005	SF	@	JAX	L 9-10	0	11	217	336	7.7	0.0
6		49ers	-1	1	10/12/2003	SF	@	SEA	L 19-20	2	19	261	333	41.7
7		49ers	-1	1	9/21/2003	SF	vs	CLE	L 12-13	0	15	265	251	33.3	0.0
8		49ers	-1	1	12/24/1995	SF	@	ATL	L 27-28	3	23	434	363	50.0	50.0
9		49ers	-1	1	10/15/1995	SF	@	IND	L 17-18	2	21	269	257	50.0	0.0
10		49ers	-1	1	10/1/1989	SF	vs	RAM	L 12-13	0	22	367	287
11		49ers	-1	1	11/6/1988	SF	@	PHX	L 23-24	2	22	357	355
12		49ers	-1	1	10/24/1988	SF	@	CHI	L 9-10	1	12	213	237
13		49ers	-1	1	11/11/1985	SF	@	DEN	L 16-17	1	16	341	336
14		49ers	-1	1	1/2/1983	SF	vs	RAM	L 20-21	3	18	324	374
15		49ers	-1	1	10/26/1980	SF	vs	TB	L 23-24	2	15	305	263
16		49ers	-1	1	10/28/1979	SF	vs	CHI	L 27-28	3	28	455	352
17		49ers	-1	1	9/17/1978	SF	@	HOU	L 19-20	2	18	382	332
18		49ers	-1	1	12/4/1977	SF	@	MIN	L 27-28	3	19	243	309
19		49ers	-1	1	10/4/1970	SF	@	ATL	L 20-21	2	18	326	356
20		49ers	-1	1	11/20/1966	SF	vs	PHI	L 34-35	4	24	404	289
21		49ers	-1	1	10/24/1965	SF	vs	MIN	L 41-42	5	21	438	549
22		49ers	-1	1	10/11/1959	SF	@	GB	L 20-21	2	13	239	371
23		49ers	-2	1	10/15/2023	SF	@	CLE	L 17-19	2	15	215	334	25.0
24		49ers	-2	1	9/26/2021	SF	vs	GB	L 28-30	4	26	298	353	63.6
25		49ers	-2	1	9/30/2018	SF	@	LAC	L 27-29	3	22	364	368	41.7

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More 49ers Stats

PASS

2,167

Purdy

Brock Purdy

RUSH

1,202

McCaffrey

Christian McCaffrey

REC

924

McCaffrey

Christian McCaffrey

PPG

25.7

10th

OPP PPG

21.8

13th

RUSH YDS/G

106.9

24th

PASS YDS/G

254.0

6th

2025 Division Standings

TEAM	W	L	T	PCT
Seahawks	14	3	0	.824
Rams	12	5	0	.706
49ers	12	5	0	.706
Cardinals	3	14	0	.176

1 - 1

6

Final

41

SEA

1 - 0

Sat 17 Jan 2026

NFL 2025 Leaders

Pass Yards Leaders

4,707

Stafford

Matthew Stafford

4,564

Goff

Jared Goff

4,552

Prescott

Dak Prescott

Rush Yards Leaders

1,621

Cook

James Cook III

1,595

Henry

Derrick Henry

1,585

Taylor

Jonathan Taylor

Rec Yards Leaders

1,793

Smith-Njigba

Jaxon Smith-Njigba

1,715

Nacua

Puka Nacua

1,429

Pickens

George Pickens

Pass TD Leaders

46

Stafford

Matthew Stafford

34

Goff

Jared Goff

31

Maye

Drake Maye

Rush TD Leaders

18

Taylor

Jonathan Taylor

16

Henry

Derrick Henry

14

Allen

Josh Allen

14

Adams

Davante Adams

11

McBride

Trey McBride

11

St. Brown

Amon-Ra St. Brown

QB Rating Leaders

113.5

Maye

Drake Maye

109.2

Stafford

Matthew Stafford

105.5

Goff

Jared Goff

23.0

Garrett

Myles Garrett

16.5

Burns

Brian Burns

15.0

Hunter

Danielle Hunter

NFL 2025 Rankings

30.5

28.8

28.4

28.3

28.3

27.9

Opp PPG Rankings

17.2

17.4

18.3

18.8

19.1

19.3

Total Yards Rankings

394.6

391.9

379.4

376.3

373.2

369.5

Rush Yards Rankings

159.6

156.6

144.5

134.7

129.1

128.9

Pass Yards Rankings

278.5

276.9

268.6

262.3

256.1

254.0

68.0

57.0

53.0

49.0

49.0

48.0

NFL Fantasy 2025

Fantasy RB Rankings

316.3

Taylor

Jonathan Taylor

314.6

McCaffrey

Christian McCaffrey

291.8

Robinson

Bijan Robinson

Fantasy WR Rankings

246

Nacua

Puka Nacua

240.9

Smith-Njigba

Jaxon Smith-Njigba

207

St. Brown

Amon-Ra St. Brown

Fantasy TE Rankings

189.9

McBride

Trey McBride

125.1

Goedert

Dallas Goedert

122.8

Pitts

Kyle Pitts Sr.

Fantasy K Rankings

202

Myers

Jason Myers

194

Fairbairn

Ka'imi Fairbairn

187.6

Aubrey

Brandon Aubrey

NFL 2025 Betting

Best Record ATS

15-5

12-6

14-7

12-6-1

12-7

11-7

Worst Record ATS

5-12

5-12-1

6-11

6-11

6-11

7-10

NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - y	14	3	0	.824
Bills - w	12	5	0	.706
Dolphins - e	7	10	0	.412
Jets - e	3	14	0	.176
AFC North	W	L	T	PCT
Steelers - y	10	7	0	.588
Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
AFC South	W	L	T	PCT
Jaguars - y	13	4	0	.765
Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
Titans - e	3	14	0	.176
AFC West	W	L	T	PCT
Broncos - z*	14	3	0	.824
Chargers - w	11	6	0	.647
Chiefs - e	6	11	0	.353
Raiders - e	3	14	0	.176

NFC East	W	L	T	PCT
Eagles - y	11	6	0	.647
Cowboys - e	7	9	1	.441
Commanders - e	5	12	0	.294
Giants - e	4	13	0	.235
NFC North	W	L	T	PCT
Bears - y	11	6	0	.647
Packers - w	9	7	1	.559
Vikings - e	9	8	0	.529
Lions - e	9	8	0	.529
NFC South	W	L	T	PCT
Panthers - y	8	9	0	.471
Buccaneers - e	8	9	0	.471
Falcons - e	8	9	0	.471
Saints - e	6	11	0	.353
NFC West	W	L	T	PCT
Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
49ers - w	12	5	0	.706
Cardinals - e	3	14	0	.176