The San Francisco 49ers had their most assists in a home game versus the Patriots on October 5, 2008, with 44 assists.
Interpreted as:
most assist in a regular-season game at sf all-time| TEAM | AST | DATE | TM | OPP | RESULT | TKL | COMB | SCK | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 44 | 10/5/2008 |  SF | vs |  NE | L 21-30 | 48 | 92 | 5.0 | 26 | 2 | 13 | 0 | 0 | 0 | 0 |
| 2 | | 49ers | 43 | 9/21/2025 | SF | vs |  ARI | W 16-15 | 34 | 77 | 1.0 | 5 | 0 | 0 | 0 | 1 | 0 | 0 |
| 3 | | 49ers | 42 | 11/7/2021 | SF | vs | ARI | L 17-31 | 46 | 88 | 2.0 | 8 | 0 | 0 | 0 | 1 | 0 | 0 |
| 4 | | 49ers | 40 | 12/12/2024 | SF | vs |  LAR | L 6-12 | 38 | 78 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | | 49ers | 40 | 10/7/2007 | SF | vs |  BAL | L 7-9 | 45 | 85 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | | 49ers | 37 | 12/24/2022 | SF | vs |  WAS | W 37-20 | 52 | 89 | 2.0 | 19 | 1 | 0 | 0 | 1 | 1 | 0 |
| 7 | | 49ers | 36 | 12/23/2007 | SF | vs |  TB | W 21-19 | 49 | 85 | 4.0 | 14 | 1 | 62 | 0 | 2 | 1 | 0 |
| 8 | | 49ers | 35 | 1/2/2022 | SF | vs |  HOU | W 23-7 | 41 | 76 | 3.0 | 27 | 1 | 2 | 0 | 2 | 0 | 0 |
| 9 | | 49ers | 35 | 12/26/2004 | SF | vs |  BUF | L 7-41 | 49 | 84 | 1.0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
| 10 | | 49ers | 33 | 10/3/2021 | SF | vs |  SEA | L 21-28 | 29 | 62 | 3.0 | 20 | 0 | 0 | 0 | 2 | 0 | 0 |
| 11 | | 49ers | 33 | 11/11/2019 | SF | vs | SEA | L 24-27 | 51 | 84 | 5.0 | 43 | 1 | 47 | 0 | 5 | 3 | 1 |
| 12 | | 49ers | 32 | 12/25/2023 | SF | vs | BAL | L 19-33 | 42 | 74 | 2.0 | 11 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | | 49ers | 32 | 10/29/2023 | SF | vs |  CIN | L 17-31 | 46 | 78 | 3.0 | 17 | 0 | 0 | 0 | 2 | 1 | 0 |
| 14 | | 49ers | 32 | 12/11/2022 | SF | vs | TB | W 35-7 | 48 | 80 | 0.0 | 0 | 2 | 36 | 0 | 2 | 1 | 0 |
| 15 | | 49ers | 32 | 11/5/2006 | SF | vs |  MIN | W 9-3 | 46 | 78 | 3.0 | 33 | 1 | 4 | 0 | 2 | 2 | 0 |
| 16 | | 49ers | 30 | 10/20/2024 | SF | vs |  KC | L 18-28 | 44 | 74 | 2.0 | 9 | 2 | 35 | 0 | 0 | 0 | 0 |
| 17 | | 49ers | 29 | 11/16/2008 | SF | vs |  STL | W 35-16 | 56 | 85 | 4.0 | 15 | 2 | 37 | 0 | 1 | 1 | 0 |
| 18 | | 49ers | 28 | 10/6/2024 | SF | vs | ARI | L 23-24 | 38 | 66 | 1.0 | 6 | 1 | 30 | 0 | 1 | 0 | 0 |
| 19 | | 49ers | 28 | 10/24/2021 | SF | vs |  IND | L 18-30 | 42 | 70 | 1.0 | 3 | 0 | 0 | 0 | 3 | 2 | 0 |
| 20 | | 49ers | 28 | 1/1/2006 | SF | vs | HOU | W 20-17 | 33 | 61 | 0.0 | 0 | 2 | 71 | 1 | 0 | 0 | 0 |
| 21 | | 49ers | 27 | 11/5/2020 | SF | vs |  GB | L 17-34 | 38 | 65 | 1.0 | 11 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 | | 49ers | 26 | 9/28/2025 | SF | vs |  JAX | L 21-26 | 40 | 66 | 0.0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| 23 | | 49ers | 26 | 12/30/2024 | SF | vs |  DET | L 34-40 | 45 | 71 | 2.0 | 16 | 0 | 0 | 0 | 0 | 0 | 0 |
| 24 | | 49ers | 26 | 9/29/2024 | SF | vs | NE | W 30-13 | 40 | 66 | 6.0 | 25 | 1 | 45 | 1 | 4 | 2 | 0 |
| 25 | | 49ers | 26 | 9/24/2006 | SF | vs |  PHI | L 24-38 | 26 | 52 | 3.0 | 30 | 0 | 0 | 0 | 1 | 1 | 0 |
StatMuse has team, game-level data for assists going back to the 2001 season.
More 49ers Stats
Team Rankings
PPG
20.8
24th
OPP PPG
21.3
15th
RUSH YDS/G
82.2
30th
PASS YDS/G
306.3
1st
NYG 
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Chargers 
Broncos | NFC East | W | L | T | PCT |
|---|---|---|---|---|
| Eagles | 4 | 2 | 0 | .667 |
| Commanders | 3 | 3 | 0 | .500 |
| NFC North | W | L | T | PCT |
| Packers | 3 | 1 | 1 | .700 |
| Lions | 4 | 2 | 0 | .667 |
| NFC South | W | L | T | PCT |
| Buccaneers | 5 | 1 | 0 | .833 |
 Falcons | 3 | 2 | 0 | .600 |
| NFC West | W | L | T | PCT |
| 49ers | 4 | 2 | 0 | .667 |
| Seahawks | 4 | 2 | 0 | .667 |
DAL 
NYJ 
LV 
TEN 
NO 
CHI 
MIA 
CLE 
