The Carolina Panthers are 43-55-1 against the AFC in the regular-season and playoffs since February 1, 2003.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Panthers | 9/7/2003 | 1-0 |  CAR | vs |  JAX | W 24-23 | 1.000 | 3 | 17 | 242 | 331 | 28.6 | 100.0 |
| 2 | | Panthers | 10/12/2003 | 1-0 | CAR | @ |  IND | W 23-20 | 1.000 | 2 | 17 | 341 | 369 | 33.3 | |
| 3 | | Panthers | 10/19/2003 | 0-1 | CAR | vs |  TEN | L 17-37 | .000 | 2 | 19 | 383 | 348 | 28.6 | 50.0 |
| 4 | | Panthers | 11/2/2003 | 0-1 | CAR | @ |  HOU | L 10-14 | .000 | 1 | 21 | 367 | 267 | 44.4 | 100.0 |
| 5 | | Panthers | 2/1/2004 | 0-1 | CAR | @ |  NE | L 29-32 | .000 | 4 | 17 | 387 | 481 | 33.3 | |
| 6 | | Panthers | 9/19/2004 | 1-0 | CAR | @ |  KC | W 28-17 | 1.000 | 4 | 23 | 358 | 281 | 42.9 | |
| 7 | | Panthers | 10/10/2004 | 0-1 | CAR | @ |  DEN | L 17-20 | .000 | 2 | 12 | 227 | 434 | 41.7 | |
| 8 | | Panthers | 10/24/2004 | 0-1 | CAR | vs |  SD | L 6-17 | .000 | 0 | 20 | 263 | 302 | 35.7 | 0.0 |
| 9 | | Panthers | 11/7/2004 | 0-1 | CAR | vs |  OAK | L 24-27 | .000 | 3 | 24 | 304 | 297 | 62.5 | |
| 10 | | Panthers | 9/18/2005 | 1-0 | CAR | vs | NE | W 27-17 | 1.000 | 3 | 17 | 250 | 288 | 35.7 | |
| 11 | | Panthers | 9/25/2005 | 0-1 | CAR | @ |  MIA | L 24-27 | .000 | 3 | 23 | 299 | 315 | 46.2 | |
| 12 | | Panthers | 11/13/2005 | 1-0 | CAR | vs |  NYJ | W 30-3 | 1.000 | 3 | 15 | 220 | 214 | 45.5 | |
| 13 | | Panthers | 11/27/2005 | 1-0 | CAR | @ |  BUF | W 13-9 | 1.000 | 1 | 19 | 295 | 216 | 64.3 | |
| 14 | | Panthers | 10/8/2006 | 1-0 | CAR | vs |  CLE | W 20-12 | 1.000 | 2 | 15 | 288 | 248 | 0.0 | |
| 15 | | Panthers | 10/15/2006 | 1-0 | CAR | @ |  BAL | W 23-21 | 1.000 | 2 | 20 | 414 | 292 | 46.7 | |
| 16 | | Panthers | 10/22/2006 | 0-1 | CAR | @ |  CIN | L 14-17 | .000 | 2 | 17 | 277 | 342 | 18.2 | |
| 17 | | Panthers | 12/17/2006 | 0-1 | CAR | vs |  PIT | L 3-37 | .000 | 0 | 12 | 240 | 306 | 23.1 | 50.0 |
| 18 | | Panthers | 9/16/2007 | 0-1 | CAR | vs | HOU | L 21-34 | .000 | 3 | 17 | 353 | 346 | 53.8 | |
| 19 | | Panthers | 10/28/2007 | 0-1 | CAR | vs | IND | L 7-31 | .000 | 1 | 20 | 293 | 395 | 47.6 | 100.0 |
| 20 | | Panthers | 11/4/2007 | 0-1 | CAR | @ | TEN | L 7-20 | .000 | 1 | 15 | 191 | 236 | 25.0 | |
| 21 | | Panthers | 12/9/2007 | 0-1 | CAR | @ | JAX | L 6-37 | .000 | 0 | 10 | 149 | 427 | 16.7 | 33.3 |
| 22 | | Panthers | 9/7/2008 | 1-0 | CAR | @ | SD | W 26-24 | 1.000 | 2 | 20 | 388 | 316 | 33.3 | 50.0 |
| 23 | | Panthers | 10/5/2008 | 1-0 | CAR | vs | KC | W 34-0 | 1.000 | 4 | 20 | 441 | 127 | 55.6 | 50.0 |
| 24 | | Panthers | 11/9/2008 | 1-0 | CAR | @ | OAK | W 17-6 | 1.000 | 2 | 10 | 219 | 259 | 23.1 | |
| 25 | | Panthers | 12/14/2008 | 1-0 | CAR | vs | DEN | W 30-10 | 1.000 | 3 | 18 | 400 | 279 | 40.0 | |
| Average | .439 | 2.1 | 18.8 | 313.0 | 324.8 | 37.9 | 0.9 | ||||||||
| Total | 43-55-1 | .439 | 211 | 1,859 | 30,987 | 32,156 | 37.9 | 53.8 | |||||||
More Panthers Stats
Team Rankings
PPG
19.3
27th
OPP PPG
24.0
20th
RUSH YDS/G
136.9
5th
PASS YDS/G
197.6
30th
2025 Division Standings
| TEAM | W | L | T | PCT |
|---|---|---|---|---|
 Buccaneers | 6 | 2 | 0 | .750 |
| Panthers | 4 | 4 | 0 | .500 |
 Falcons | 3 | 4 | 0 | .429 |
 Saints | 1 | 7 | 0 | .125 |
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