Between May 28, 2015 and May 28, 2025, the Columbus Blue Jackets have the highest goal differential by a team in a game, with a differential of 10 goals against the Canadiens on November 4, 2016.

biggest win margin in one regular-season game in NHL last 10 years

	TEAM	DIFF	DATE	TM		OPP	RESULT	G	GA	PPG	PPO	OPP PPG	OPP PPO	S	SA
1	Blue Jackets	10	11/4/2016	CBJ	vs	MTL	W 10-0	10	0	4	5	0	1	40	30
2	Canucks	9	11/2/2023	VAN	@	SJS	W 10-1	10	1	4	5	1	3	33	31
3	Penguins	9	3/27/2022	PIT	vs	DET	W 11-2	11	2	3	6	1	5	35	35
4	Rangers	9	3/17/2021	NYR	vs	PHI	W 9-0	9	0	1	4	0	2	29	26
5	Canadiens	9	12/2/2017	MTL	vs	DET	W 10-1	10	1	1	2	0	1	34	23
6	Blackhawks	9	10/5/2017	CHI	vs	PIT	W 10-1	10	1	0	6	1	2	44	29
7	Canadiens	9	12/10/2016	MTL	vs	COL	W 10-1	10	1	1	2	0	3	36	16
8	Lightning	8	3/27/2025	TBL	vs	UTA	W 8-0	8	0	1	2	0	2	22	25
9	Penguins	8	11/4/2023	PIT	@	SJS	W 10-2	10	2	2	4	2	6	35	26
10	Canadiens	8	4/29/2022	MTL	vs	FLA	W 10-2	10	2	1	2	1	1	37	39
11	Flames	8	4/16/2022	CGY	vs	ARI	W 9-1	9	1	0	2	0	2	41	26
12	Predators	8	3/5/2022	NSH	@	SJS	W 8-0	8	0	1	4	0	3	36	20
13	Blues	8	4/9/2021	STL	vs	MIN	W 9-1	9	1	1	2	0	2	38	25
14	Avalanche	8	1/15/2021	COL	vs	STL	W 8-0	8	0	5	7	0	4	38	21
15	Penguins	8	10/25/2018	PIT	@	CGY	W 9-1	9	1	2	2	0	3	36	39
16	Blue Jackets	7	4/12/2025	CBJ	vs	WSH	W 7-0	7	0	0	2	0	2	26	22
17	Rangers	7	4/10/2025	NYR	@	NYI	W 9-2	9	2	1	1	1	2	32	46
18	Kings	7	3/30/2025	LAK	vs	SJS	W 8-1	8	1	2	5	0	3	36	23
19	Penguins	7	12/12/2024	PIT	@	MTL	W 9-2	9	2	2	3	0	4	33	23
20	Jets	7	12/10/2024	WPG	vs	BOS	W 8-1	8	1	3	6	1	2	35	24
21	Lightning	7	12/5/2024	TBL	vs	SJS	W 8-1	8	1	1	2	0	3	35	21
22	Capitals	7	11/9/2024	WSH	@	STL	W 8-1	8	1	2	2	0	3	27	25
23	Senators	7	10/29/2024	OTT	vs	STL	W 8-1	8	1	2	3	1	4	35	27
24	Oilers	7	4/15/2024	EDM	vs	SJS	W 9-2	9	2	0	0	0	1	38	21
25	Jets	7	4/13/2024	WPG	@	COL	W 7-0	7	0	2	3	0	1	26	30