Brent Burns has the most games with 1+ blocked shot and 1+ takeaway, with 427 games.

Interpreted as:

most regular-season games by a player with 1 or more block and 1 or more takeaway

	NAME	GP	BKS	TKA	G	A	P	+/-	PIM	PPG	PPA	SHG	SHA	GWG	OTG	S	S%	FOW	FO	FOW%	HIT	GVA	TOI/GP
1	Brent Burns B. Burns	427	831	616	74	207	281	+27	221	24	83	1	4	18	7	1,219	6.1	10	28	35.7	446	488	24:04
2	Erik Karlsson E. Karlsson	392	746	593	73	257	330	-22	174	16	98	0	4	16	5	1,097	6.7	0	3	0.0	299	487	25:59
3	Alex Pietrangelo A. Pietrangelo	392	893	574	57	179	236	+80	128	18	62	0	4	13	1	962	5.9	1	3	33.3	294	226	24:46
4	Duncan Keith D. Keith	368	785	512	37	173	210	+76	154	9	48	1	6	4	1	789	4.7	0	1	0.0	198	349	25:05
5	John Carlson J. Carlson	363	844	502	55	211	266	+96	108	17	78	0	2	16	1	867	6.3	1	2	50.0	334	385	23:54
6	Zdeno Chara Z. Chara	361	713	477	50	97	147	+63	352	23	31	2	4	4	0	786	6.4	5	13	38.5	947	347	24:34
7	Kris Letang K. Letang	341	672	470	60	177	237	+29	236	13	74	2	3	12	6	909	6.6	0	2	0.0	687	355	25:19
8	Andrei Markov A. Markov	329	667	483	37	160	197	+12	183	16	80	2	6	5	0	562	6.6	1	2	50.0	213	442	23:30
9	Jaccob Slavin J. Slavin	328	671	563	21	105	126	+49	44	3	9	2	9	4	2	570	3.7	0	1	0.0	187	209	22:45
10	Victor Hedman V. Hedman	325	673	418	50	178	228	+69	208	11	70	0	6	10	5	704	7.1	0	1	0.0	364	290	24:15
11	Ryan McDonagh R. McDonagh	322	788	420	36	105	141	+116	113	5	18	1	4	6	2	547	6.6	1	3	33.3	341	278	23:15
12	Mark Giordano M. Giordano	319	736	433	47	147	194	+33	278	15	56	6	5	5	3	716	6.6	0	0		318	224	23:31
13	Ryan Suter R. Suter	311	603	378	24	126	150	+50	177	11	48	0	3	3	0	520	4.6	0	0		279	174	25:11
14	Ryan Getzlaf R. Getzlaf	292	474	424	65	230	295	+40	230	20	78	3	1	10	1	629	10.3	2,221	4,585	48.4	512	305	20:18
15	Joe Pavelski J. Pavelski	289	449	388	106	149	255	+68	110	42	49	2	4	21	2	855	12.4	1,892	3,422	55.3	306	194	19:05
16	TJ Brodie	288	550	392	17	97	114	+36	98	3	18	0	4	3	1	301	5.6	0	0		134	294	22:28
17	Anze Kopitar A. Kopitar	287	414	389	84	165	249	+54	68	23	56	4	4	13	2	689	12.2	2,810	5,310	52.9	265	195	21:01
18	Patrice Bergeron P. Bergeron	286	406	397	89	161	250	+86	104	24	45	9	5	10	1	915	9.7	3,282	5,765	56.9	225	108	19:04
19	Dan Hamhuis D. Hamhuis	278	497	392	15	91	106	+44	115	4	13	1	4	3	0	423	3.5	0	0		377	200	22:16
20	Ryan O'Reilly R. O'Reilly	275	360	425	77	129	206	-9	36	22	47	1	1	17	6	594	13.0	2,802	5,071	55.3	119	125	19:53
21	Justin Faulk J. Faulk	274	537	391	31	89	120	-37	125	10	32	1	4	7	2	654	4.7	0	0		467	214	23:20
22	Ryan Kesler R. Kesler	271	412	374	81	105	186	+28	256	25	31	5	2	12	0	684	11.8	2,641	4,775	55.3	366	101	19:26
23	Tyler Myers T. Myers	266	505	330	36	76	112	+18	201	6	17	2	4	10	1	441	8.2	0	1	0.0	314	198	22:31
24	Erik Johnson E. Johnson	262	569	347	26	67	93	+26	144	5	22	0	3	4	1	546	4.8	0	1	0.0	446	143	22:27
25	Marc Staal M. Staal	258	461	317	15	50	65	+9	108	3	7	1	1	1	0	284	5.3	2	3	66.7	415	142	21:10