Jewell Loyd has the most career games by a guard, with 371 games.

Interpreted as:

most regular-season games played by a pg

	NAME	GP	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	PTS	REB	AST	STL	BLK	TOV	PF	+/-
1	Jewell Loyd J. Loyd	371	30.2	16.2	3.6	3.1	1.2	0.2	5.4	13.5	40.1	1.8	5.1	35.2	3.6	4.1	88.2	53.1	0.9	2.7	2.1	11,194	6,027	1,331	1,133	441	91	780	644	+932
2	Chelsea Gray C. Gray	369	28.2	11.9	3.2	5.1	1.2	0.3	4.5	9.8	45.9	1.1	2.9	38.0	1.9	2.2	86.7	55.8	0.4	2.8	2.4	10,413	4,409	1,188	1,870	436	119	869	603	+1909
3	Erica Wheeler E. Wheeler	341	23.5	9.0	2.5	3.7	1.0	0.1	3.4	8.5	39.9	0.9	2.8	33.8	1.2	1.5	82.5	48.8	0.4	2.1	2.0	8,012	3,060	852	1,256	342	39	665	758	-719
4	Kayla McBride K. McBride	340	30.7	14.6	3.2	2.6	1.1	0.1	4.8	11.6	41.3	2.0	5.3	37.2	3.0	3.3	90.0	55.5	0.4	2.8	1.7	10,433	4,947	1,103	887	385	36	580	469	+329
5	Courtney Williams C. Williams	333	27.7	12.2	5.2	4.1	0.9	0.3	5.3	12.1	43.6	0.8	2.0	37.4	0.9	1.2	75.1	48.4	1.1	4.2	1.9	9,219	4,061	1,747	1,365	308	101	643	553	+880
6	Natasha Cloud N. Cloud	327	28.2	8.8	3.3	5.3	1.0	0.2	3.0	7.7	39.0	1.0	3.2	31.3	1.7	2.1	81.2	50.5	0.3	3.0	2.0	9,223	2,863	1,080	1,733	340	81	665	718	+578
7	Kahleah Copper K. Copper	319	24.1	12.8	3.6	1.5	0.6	0.1	4.6	10.5	44.4	1.1	3.0	35.3	2.4	3.1	79.3	54.2	0.6	2.9	1.8	7,696	4,083	1,140	463	207	45	579	715	-202
8	Courtney Vandersloot C. Vandersloot	317	28.6	10.8	3.5	7.3	1.3	0.4	4.0	8.8	46.2	1.0	2.9	34.0	1.7	2.1	82.8	55.8	0.5	2.9	2.6	9,077	3,419	1,100	2,317	409	136	813	634	+978
9	Sami Whitcomb S. Whitcomb	307	19.3	7.2	2.4	2.0	0.8	0.2	2.4	6.2	39.3	1.7	4.6	36.1	0.7	0.8	86.3	55.0	0.4	2.0	1.4	5,911	2,211	726	623	246	56	416	480	-82
10	Tiffany Mitchell T. Mitchell	305	21.4	8.1	2.2	1.6	0.7	0.1	2.7	7.0	38.2	0.5	1.7	28.0	2.3	2.6	87.4	49.9	0.6	1.7	1.4	6,540	2,480	684	488	209	36	439	604	-855
11	Rachel Banham R. Banham	303	15.3	5.8	1.2	1.6	0.4	0.1	2.0	5.2	38.6	1.2	3.3	36.7	0.6	0.7	81.8	52.9	0.1	1.1	0.9	4,636	1,768	369	495	112	37	284	472	-208
12	Allisha Gray A. Gray	300	30.6	13.9	4.5	2.4	1.2	0.5	4.6	10.7	43.0	1.4	4.0	35.5	3.2	4.0	81.4	55.7	1.2	3.3	1.5	9,192	4,157	1,347	730	349	151	449	706	+90
13	Tiffany Hayes T. Hayes	285	27.8	13.8	3.3	2.5	1.0	0.2	4.6	10.4	44.0	1.3	3.7	34.7	3.4	4.2	79.9	56.3	0.8	2.5	1.7	7,934	3,937	941	722	289	63	474	767	+135
14	Odyssey Sims O. Sims	282	26.0	10.4	2.4	3.8	1.0	0.1	3.8	9.5	39.6	0.6	2.4	26.5	2.3	2.8	81.0	48.6	0.5	1.9	1.9	7,343	2,945	680	1,059	282	29	546	510	+60
15	Brittney Sykes B. Sykes	279	27.2	12.3	4.0	2.9	1.3	0.5	4.4	10.6	41.1	0.8	2.7	30.2	2.7	3.6	75.6	50.2	0.8	3.2	2.0	7,588	3,425	1,105	814	351	129	556	662	-189
16	Kelsey Plum K. Plum	278	29.8	15.1	2.6	4.3	0.9	0.1	5.1	11.8	43.0	2.1	5.5	38.3	2.9	3.2	88.5	57.2	0.3	2.2	2.2	8,277	4,207	715	1,193	253	21	611	658	+1066
17	Kelsey Mitchell K. Mitchell	277	30.6	17.4	2.0	2.9	0.8	0.1	6.1	14.2	43.1	2.4	6.3	38.1	2.7	3.3	82.8	55.5	0.4	1.6	2.0	8,464	4,813	548	799	217	40	549	579	-886
18	Shatori Walker-Kimbrough S. Walker-Kimbrough	274	17.4	5.6	1.5	1.2	0.7	0.3	1.9	4.6	42.2	0.6	1.8	35.0	1.1	1.3	88.2	54.8	0.3	1.2	0.9	4,769	1,544	408	326	204	84	242	282	-3
19	Skylar Diggins S. Diggins	269	32.1	16.9	3.0	5.5	1.3	0.7	5.6	13.1	42.5	1.4	4.1	33.7	4.3	5.1	84.4	54.9	0.7	2.3	2.6	8,648	4,534	808	1,475	353	193	689	637	+534
20	Sydney Colson S. Colson	255	11.1	2.9	0.8	1.7	0.6	0.1	1.0	2.5	39.8	0.2	0.8	31.0	0.6	0.8	78.6	49.9	0.2	0.6	0.9	2,839	728	200	444	158	30	228	309	-385
21	Jasmine Thomas J. Thomas	254	26.5	10.1	2.8	4.1	1.2	0.2	3.7	9.7	38.5	1.1	3.4	33.9	1.5	1.8	83.5	48.3	0.5	2.2	2.2	6,738	2,574	700	1,036	295	61	558	464	+587
22	Ariel Atkins A. Atkins	251	27.8	13.4	3.0	2.6	1.5	0.4	4.7	11.1	42.6	1.8	4.8	36.2	2.2	2.6	85.0	54.9	0.9	2.2	1.7	6,981	3,361	758	646	364	109	437	684	+504
23	Kia Nurse K. Nurse	245	23.5	8.9	2.4	1.6	0.5	0.1	2.8	7.9	36.1	1.5	4.5	32.6	1.8	2.1	84.3	50.7	0.5	2.0	1.3	5,749	2,188	598	397	133	20	313	463	-1182
24	Allie Quigley A. Quigley	245	26.1	13.1	2.4	2.4	0.6	0.3	4.9	10.5	46.3	1.8	4.6	40.0	1.6	1.7	89.8	58.1	0.4	2.0	1.5	6,394	3,214	582	596	154	75	370	375	+181
25	Jackie Young J. Young	243	30.0	14.0	4.1	4.2	1.1	0.3	5.0	10.8	46.7	1.3	3.4	37.8	2.7	3.1	86.0	57.7	0.9	3.3	1.7	7,281	3,412	1,002	1,029	271	64	424	503	+1576