Sheryl Swoopes has played the most minutes in a game, with 55 minutes on the court versus the Mercury on August 10, 2006.

Interpreted as:

most minutes by a player in one regular-season game all-time

	NAME	MIN	DATE	TM		OPP	PTS	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	+/-
1	Sheryl Swoopes S. Swoopes	55	8/10/2006	HOU	vs	PHX	30	8	6	2	2	11	23	47.8	1	6	16.7	7	9	77.8	55.6	0	8	4	3	-1
2	Vicky Bullett V. Bullett	55	7/3/2001	WAS	@	SEA	5	11	2	2	3	1	12	8.3	1	4	25.0	2	3	66.7	18.8	3	8	3	1	+1
3	Lauren Jackson L. Jackson	55	7/3/2001	SEA	vs	WAS	24	12	0	3	5	10	29	34.5	3	6	50.0	1	2	50.0	40.2	2	10	1	3	-1
4	Audrey Sauret A. Sauret	54	7/3/2001	WAS	@	SEA	7	7	3	2	0	3	6	50.0	0	1	0.0	1	1	100.0	54.3	4	3	2	2	-1
5	Chamique Holdsclaw C. Holdsclaw	54	7/3/2001	WAS	@	SEA	15	15	3	0	2	5	19	26.3	0	0		5	10	50.0	32.1	3	12	5	1	-1
6	Chasity Melvin C. Melvin	53	6/8/2002	CLE	@	ORL	23	6	1	1	2	8	13	61.5	0	0		7	10	70.0	66.1	3	3	1	4	0
7	Lindsey Harding L. Harding	52	6/1/2014	LAS	@	WAS	13	2	4	2	0	5	18	27.8	2	4	50.0	1	1	100.0	35.2	1	1	2	3	-1
8	Kelly Miller K. Miller	52	8/10/2006	PHX	@	HOU	9	7	5	1	0	3	7	42.9	0	0		3	4	75.0	51.4	1	6	2	5	+3
9	Candice Dupree C. Dupree	52	7/14/2010	PHX	vs	SEA	18	14	1	2	0	9	18	50.0	0	0		0	0		50.0	4	10	1	3	-6
10	Tina Thompson T. Thompson	52	7/22/2009	LAS	@	SEA	22	6	2	1	1	7	14	50.0	2	5	40.0	6	7	85.7	64.4	1	5	5	5	-10
11	Tina Thompson T. Thompson	52	8/10/2006	HOU	vs	PHX	37	16	8	1	0	13	27	48.1	2	5	40.0	9	12	75.0	57.3	8	8	5	3	+8
12	Shameka Christon S. Christon	51	6/26/2008	NYL	vs	IND	23	5	2	0	0	5	17	29.4	2	5	40.0	11	12	91.7	51.6	2	3	5	3	+7
13	Camille Little C. Little	51	7/22/2009	SEA	vs	LAS	17	14	2	2	0	7	12	58.3	0	1	0.0	3	3	100.0	63.8	5	9	2	1	+10
14	Kristen Rasmussen K. Rasmussen	51	8/10/2006	PHX	@	HOU	2	10	1	2	0	1	3	33.3	0	1	0.0	0	0		33.3	2	8	2	4	+3
15	Penny Taylor P. Taylor	51	7/14/2010	PHX	vs	SEA	16	6	5	1	0	5	11	45.5	3	5	60.0	3	3	100.0	64.9	0	6	5	5	-3
16	Shannon Johnson S. Johnson	50	6/8/2002	ORL	vs	CLE	35	6	2	2	0	11	17	64.7	2	4	50.0	11	12	91.7	78.5	2	4	4	5	-1
17	Tammy Sutton-Brown T. Sutton-Brown	50	6/26/2008	IND	@	NYL	23	15	3	2	2	10	13	76.9	0	0		3	4	75.0	77.9	6	9	7	5	-2
18	Sue Bird S. Bird	50	7/14/2010	SEA	@	PHX	14	5	8	2	0	6	18	33.3	2	8	25.0	0	0		38.9	0	5	3	2	+4
19	Dawn Staley D. Staley	50	8/10/2006	HOU	vs	PHX	11	1	7	2	1	3	8	37.5	2	6	33.3	3	4	75.0	56.4	0	1	1	1	-8
20	Arike Ogunbowale A. Ogunbowale	50	6/9/2024	DAL	vs	PHX	25	7	10	4	0	9	27	33.3	3	11	27.3	4	6	66.7	42.2	2	5	3	3	-7
21	Nikki Teasley N. Teasley	50	7/15/2003	LAS	vs	PHX	10	7	9	3	1	4	7	57.1	0	3	0.0	2	3	66.7	60.1	0	7	9	3	+3
22	La'Keshia Frett L. Frett	50	6/13/2002	SAC	vs	NYL	14	7	1	0	2	7	9	77.8	0	1	0.0	0	0		77.8	3	4	0	3	+1
23	Merlakia Jones M. Jones	50	6/8/2002	CLE	@	ORL	17	8	4	2	0	5	16	31.3	0	1	0.0	7	8	87.5	43.5	1	7	3	4	+4
24	Adrienne Johnson A. Johnson	50	8/9/2000	ORL	@	MIA	13	4	3	2	0	5	12	41.7	1	7	14.3	2	2	100.0	50.5	2	2	2	3	-4
25	Tina Thompson T. Thompson	50	6/30/1998	HOU	@	UTA	9	14	1	2	1	2	15	13.3	0	8	0.0	5	5	100.0	26.2	5	9	2	1	+2