David De Gea has the most saves in a Premier League match, with 14 saves versus Arsenal on December 2, 2017.

Interpreted as:

most saves by a player in one match all-time

	NAME	SV	DATE	CLUB		OPP	Rating	MIN	GC	SV-PK	CS	ERR-SH	ERR-G	PKC	OG	TKL	FOUL	YC	RC
1	David De Gea D. De Gea	14	12/2/2017	Man United	@	Arsenal		90	1	0	0	0	0	0	0	0	0	0	0
2	Mads Hermansen M. Hermansen	13	9/28/2024	Leicester	@	Arsenal	8.7	90	4	0	0	1	0	0	0	0	0	0	0
3	Vito Mannone V. Mannone	13	1/2/2017	Sunderland	vs	Liverpool		90	2	0	0	0	0	0	0	0	0	0	0
4	Łukasz Fabiański Ł. Fabiański	13	2/28/2016	Swansea	@	Tottenham		90	2	0	0	0	0	0	0	0	0	0	0
5	Boaz Myhill B. Myhill	13	3/21/2015	West Brom	@	Man City		90	3	0	0	0	0	0	0	0	0	0	0
6	Mark Flekken M. Flekken	12	2/5/2024	Brentford	vs	Man City	7.6	90	3	0	0	0	0	0	0	0	0	0	0
7	Paulo Gazzaniga P. Gazzaniga	12	10/27/2019	Tottenham	@	Liverpool		90	2	0	0	0	0	0	0	0	0	0	0
8	Wayne Hennessey W. Hennessey	12	8/19/2017	Crystal Palace	@	Liverpool		90	1	0	0	0	0	0	0	0	0	0	0
9	José Sá J. Sá	11	5/19/2024	Wolves	@	Liverpool	8.7	90	2	0	0	0	0	0	0	0	0	0	0
10	Arijanet Muric A. Muric	11	3/30/2024	Burnley	@	Chelsea	8.6	90	2	0	0	0	0	0	0	1	0	0	0
11	David Raya D. Raya	11	4/1/2023	Brentford	@	Brighton	7.3	90	3	0	0	1	0	0	0	0	0	0	0
12	Karl Darlow K. Darlow	11	9/27/2020	Newcastle	@	Tottenham		90	1	0	0	0	0	0	0	0	0	0	0
13	David De Gea D. De Gea	11	1/13/2019	Man United	@	Tottenham		90	0	0	1	0	0	0	0	0	0	0	0
14	Jordan Pickford J. Pickford	11	5/16/2017	Sunderland	@	Arsenal		90	2	0	0	0	0	0	0	0	0	0	0
15	Tom Heaton T. Heaton	11	10/29/2016	Burnley	@	Man United		90	0	0	1	0	0	0	0	0	0	1	0
16	Tom Heaton T. Heaton	11	10/16/2016	Burnley	@	Southampton		90	3	0	0	0	0	0	0	0	0	0	0
17	Alphonse Aréola A. Aréola	10	11/22/2025	West Ham	@	Bournemouth	8.3	90	2	0	0	0	0	0	0	0	0	0	0
18	Mark Flekken M. Flekken	10	11/4/2024	Brentford	@	Fulham	8.1	90	2	0	0	0	0	0	0	0	0	0	0
19	Arijanet Muric A. Muric	10	4/20/2024	Burnley	@	Sheffield Utd	9.2	90	1	0	0	1	0	0	0	0	0	0	0
20	Martin Dúbravka M. Dúbravka	10	1/1/2024	Newcastle	@	Liverpool	8.3	90	4	1	0	0	0	1	0	0	1	1	0
21	James Trafford J. Trafford	10	12/9/2023	Burnley	@	Brighton	9.3	90	1	0	0	0	0	0	0	0	0	0	0
22	Alphonse Aréola A. Aréola	10	9/16/2023	West Ham	vs	Man City	8.1	90	3	0	0	0	0	0	0	0	0	0	0
23	Álvaro Fernández Á. Fernández	10	1/16/2022	Brentford	@	Liverpool	7.6	90	3	0	0	0	1	0	0	0	0	0	0
24	Fraser Forster F. Forster	10	12/28/2021	Southampton	vs	Tottenham	8.9	90	1	0	0	0	0	0	0	0	0	0	0
25	Roberto Jiménez R. Jiménez	10	11/9/2019	West Ham	@	Burnley		90	3	0	0	0	0	0	1	0	0	0	0