Chris Sale has a record of 46-30 with an ERA of 3.27 and 945 strikeouts in 115 appearances for the Red Sox in his career.
| NAME | SEASON | TM | G | W | L | W% | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | C. Sale | 2017 |  BOS | 32 | 17 | 8 | .680 | 32 | 2.90 | 308 | 1 | 0 | 0 | 214.1 | 165 | 69 | 73 | 24 | 43 | 8 | 0 | 0 | 851 | 3 | 12.93 | 1.81 | 7.16 | 1.01 | 36.2 | 5.1 | 0.97 | .301 | 3.07 | 63 | 2.45 | 56 | 6.93 | 45.5 |
| 2 | | C. Sale | 2018 | BOS | 27 | 12 | 4 | .750 | 27 | 2.11 | 237 | 0 | 0 | 0 | 158.0 | 102 | 37 | 39 | 11 | 34 | 14 | 0 | 0 | 617 | 4 | 13.50 | 1.94 | 6.97 | 0.63 | 38.4 | 5.5 | 0.86 | .283 | 2.22 | 48 | 1.97 | 47 | 5.81 | 39.2 |
| 3 | | C. Sale | 2019 | BOS | 25 | 6 | 11 | .353 | 25 | 4.40 | 218 | 1 | 1 | 0 | 147.1 | 123 | 72 | 80 | 24 | 37 | 13 | 0 | 0 | 612 | 2 | 13.32 | 2.26 | 5.89 | 1.47 | 35.6 | 6.0 | 1.09 | .309 | 4.89 | 91 | 3.38 | 75 | 7.51 | 18.8 |
| 4 | | C. Sale | 2021 | BOS | 9 | 5 | 1 | .833 | 9 | 3.16 | 52 | 0 | 0 | 0 | 42.2 | 45 | 15 | 19 | 6 | 12 | 4 | 0 | 1 | 183 | 0 | 10.97 | 2.53 | 4.33 | 1.27 | 28.4 | 6.6 | 1.34 | .358 | 4.01 | 69 | 3.68 | 85 | 9.49 | 3 |
| 5 | | C. Sale | 2022 | BOS | 2 | 0 | 1 | .000 | 2 | 3.18 | 5 | 0 | 0 | 0 | 5.2 | 5 | 2 | 3 | 0 | 1 | 1 | 0 | 0 | 25 | 0 | 7.94 | 1.59 | 5.00 | 0.00 | 20.0 | 4.0 | 1.06 | .278 | 4.76 | 77 | 2.40 | 60 | 7.94 | 1 |
| 6 | | C. Sale | 2023 | BOS | 20 | 6 | 5 | .545 | 20 | 4.30 | 125 | 0 | 0 | 0 | 102.2 | 87 | 49 | 52 | 15 | 29 | 8 | 0 | 0 | 425 | 3 | 10.96 | 2.54 | 4.31 | 1.31 | 29.4 | 6.8 | 1.13 | .290 | 4.56 | 95 | 3.80 | 88 | 7.63 | 6 |
| Total | 115 | 46 | 30 | .605 | 115 | 3.27 | 945 | 2 | 1 | 0 | 670.2 | 527 | 244 | 266 | 80 | 156 | 48 | 0 | 1 | 2,713 | 12 | 12.68 | 2.09 | 6.06 | 1.07 | 34.8 | 5.8 | 1.02 | .301 | 3.57 | 71 | 2.82 | 65 | 7.07 | 113.5 |
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