6 players were tied for the most runs in a game in 2000, with 5 runs. The first three are Luis Alicea on August 31, 2000, Larry Walker on July 27, 2000 and Jeff Cirillo on June 28, 2000.

Interpreted as:

highest scoring by a player baseball regular-season game 2000

	NAME	R	DATE	TM		OPP	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Luis Alicea L. Alicea	5	8/31/2000	TEX	vs	CLE	5	4	1	0	1	2	1	0	0	0	0	6	8	2	0	0	0	0
2	Larry Walker L. Walker	5	7/27/2000	COL	vs	LAD	4	4	1	0	1	2	1	0	0	0	0	5	8	2	0	0	0	0
3	Jeff Cirillo J. Cirillo	5	6/28/2000	COL	vs	SFG	5	4	1	0	3	6	1	0	0	0	0	6	14	4	0	0	0	0
4	Barry Bonds B. Bonds	5	4/18/2000	SFG	@	CIN	2	1	0	0	1	2	4	0	0	0	0	6	4	1	0	0	1	0
5	Al Martin A. Martin	5	4/16/2000	SDP	vs	HOU	5	4	0	0	1	2	0	0	0	1	0	5	7	1	0	0	0	0
6	Alex Rodriguez A. Rodriguez	5	4/16/2000	SEA	@	TOR	5	4	0	0	3	7	1	0	1	0	0	6	13	3	0	0	0	0
7	Alex Rodriguez A. Rodriguez	4	9/30/2000	SEA	@	ANA	6	4	0	0	2	7	0	0	1	0	0	7	10	2	0	1	0	0
8	Jeromy Burnitz J. Burnitz	4	9/29/2000	MIL	@	HOU	4	3	0	0	1	2	2	0	0	0	0	6	6	1	0	0	0	0
9	Dmitri Young D. Young	4	9/28/2000	CIN	@	MIL	4	4	0	2	0	0	0	0	0	0	0	4	8	2	0	0	0	0
10	Brady Anderson B. Anderson	4	9/28/2000	BAL	vs	TOR	2	2	1	0	1	4	2	0	0	0	0	5	6	2	0	1	0	0
11	Brook Fordyce B. Fordyce	4	9/28/2000	BAL	vs	TOR	5	4	0	0	1	2	0	0	0	0	0	5	7	1	0	0	0	0
12	Jerry Hairston J. Hairston	4	9/28/2000	BAL	vs	TOR	6	2	0	0	0	2	0	0	1	0	0	6	2	0	0	0	0	0
13	Nomar Garciaparra N. Garciaparra	4	9/23/2000	BOS	vs	BAL	3	2	0	0	1	2	2	0	0	0	0	5	5	1	0	0	1	0
14	Todd Hollandsworth T. Hollandsworth	4	9/20/2000	COL	vs	SDP	3	2	2	0	0	0	2	0	0	0	0	5	4	2	0	0	0	0
15	Ryan Klesko R. Klesko	4	9/20/2000	SDP	@	COL	2	1	0	0	0	1	3	0	1	0	0	5	1	0	0	0	0	0
16	Miguel Tejada M. Tejada	4	9/18/2000	OAK	@	BAL	4	3	1	0	1	3	1	0	0	0	0	5	7	2	0	0	0	0
17	Moises Alou M. Alou	4	9/15/2000	HOU	vs	PIT	5	3	2	0	1	4	0	0	0	0	0	5	8	3	0	0	0	0
18	Jeremy Giambi J. Giambi	4	9/15/2000	OAK	@	TBD	4	2	0	0	1	1	2	0	0	0	0	6	5	1	0	0	0	0
19	Richard Hidalgo R. Hidalgo	4	9/8/2000	HOU	@	CHC	4	3	1	0	0	3	1	0	1	0	0	5	4	1	0	0	0	0
20	Jose Offerman J. Offerman	4	9/7/2000	BOS	vs	MIN	4	3	1	0	2	2	1	0	1	0	0	5	10	3	0	0	0	0
21	Kenny Lofton K. Lofton	4	9/3/2000	CLE	vs	BAL	7	4	0	0	1	1	1	0	1	5	0	8	7	1	0	0	1	0
22	Jeff Bagwell J. Bagwell	4	8/22/2000	HOU	vs	CHC	3	3	2	0	1	2	1	0	0	0	0	4	8	3	0	0	0	0
23	Chipper Jones C. Jones	4	8/20/2000	ATL	@	SFG	5	4	0	0	2	2	0	0	0	1	0	5	10	2	0	0	0	0
24	Jose Valentin J. Valentin	4	8/20/2000	CWS	vs	TBD	4	3	1	0	0	3	2	0	1	2	0	6	4	1	0	0	0	0
25	Neifi Perez N. Perez	4	8/12/2000	COL	@	MON	6	3	0	0	1	1	0	0	0	0	0	6	6	1	0	0	0	0