Between October 4, 2005 and October 4, 2025, Albert Pujols has hit the most home runs, with 502 home runs.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Albert Pujols A. Pujols	502	2,290	8,467	1,285	2,402	459	5	1,597	972	79	1,060	88	28	9,613	4,377	966	0	95	246	332	.284	.359	.517	.876
2	Nelson Cruz N. Cruz	464	2,047	7,496	1,089	2,052	371	15	1,325	736	86	1,916	84	32	8,380	3,845	850	2	60	78	179	.274	.343	.513	.856
3	Giancarlo Stanton G. Stanton	453	1,726	6,274	943	1,619	313	11	1,169	805	54	2,059	42	15	7,173	3,313	777	0	40	91	158	.258	.345	.528	.874
4	Miguel Cabrera M. Cabrera	433	2,392	8,826	1,305	2,715	532	11	1,591	1,101	64	1,748	34	17	10,080	4,568	976	1	88	218	312	.308	.385	.518	.903
5	Edwin Encarnacion E. Encarnacion	415	1,891	6,829	1,074	1,783	354	10	1,230	883	102	1,366	58	14	7,880	3,402	779	0	66	52	177	.261	.351	.498	.849
6	Mike Trout M. Trout	404	1,648	5,966	1,196	1,754	325	55	1,018	1,067	106	1,662	214	38	7,200	3,401	784	0	61	130	75	.294	.407	.570	.977
7	Paul Goldschmidt P. Goldschmidt	372	2,074	7,608	1,280	2,190	477	24	1,232	1,086	53	1,979	174	36	8,804	3,831	873	0	57	121	174	.288	.378	.504	.882
8	Manny Machado M. Machado	369	1,894	7,424	1,082	2,069	396	18	1,144	663	30	1,433	113	41	8,195	3,608	783	14	64	72	224	.279	.338	.486	.824
9	Aaron Judge A. Judge	368	1,145	4,105	873	1,205	203	7	830	817	40	1,369	65	21	4,995	2,526	578	0	33	104	116	.294	.413	.615	1.028
10	Freddie Freeman F. Freeman	367	2,179	8,114	1,379	2,431	547	33	1,322	1,070	113	1,763	104	32	9,363	4,145	947	0	66	142	172	.300	.386	.511	.897
11	David Ortiz D. Ortiz	364	1,516	5,532	912	1,595	398	10	1,142	898	23	1,071	12	7	6,507	3,105	772	1	53	171	167	.288	.387	.561	.948
12	Bryce Harper B. Harper	363	1,785	6,435	1,154	1,801	401	24	1,051	1,105	52	1,654	152	52	7,665	3,339	788	13	60	137	139	.280	.387	.519	.905
13	Ryan Howard R. Howard	358	1,465	5,356	791	1,374	255	19	1,126	674	57	1,730	12	4	6,140	2,741	632	0	53	146	108	.257	.343	.512	.855
14	Joey Votto J. Votto	356	2,056	7,252	1,171	2,135	459	22	1,144	1,365	81	1,640	80	29	8,746	3,706	837	0	48	147	168	.294	.409	.511	.920
15	Nolan Arenado N. Arenado	353	1,787	6,807	992	1,921	405	34	1,184	577	43	1,094	31	23	7,512	3,453	792	5	80	80	202	.282	.338	.507	.846
16	Ryan Braun R. Braun	352	1,766	6,622	1,080	1,963	408	49	1,154	586	77	1,363	216	60	7,329	3,525	809	0	44	56	179	.296	.358	.532	.891
17	Jose Bautista J. Bautista	344	1,723	5,935	1,013	1,474	308	17	972	1,022	80	1,347	69	31	7,117	2,848	669	22	58	58	167	.248	.363	.480	.843
18	Evan Longoria E. Longoria	342	1,986	7,306	1,017	1,930	431	26	1,159	730	72	1,696	58	19	8,206	3,439	799	1	97	87	206	.264	.333	.471	.804
19	Kyle Schwarber K. Schwarber	340	1,291	4,544	800	1,050	175	14	784	764	50	1,527	37	19	5,384	2,273	529	1	25	47	53	.231	.346	.500	.846
20	Curtis Granderson C. Granderson	336	2,001	7,049	1,197	1,750	339	91	917	911	67	1,865	152	49	8,104	3,279	766	28	49	31	61	.248	.338	.465	.803
21	Carlos Santana C. Santana	335	2,204	7,815	1,107	1,880	404	17	1,136	1,330	43	1,540	65	18	9,254	3,323	756	0	66	66	188	.241	.352	.425	.777
22	Andrew McCutchen A. McCutchen	332	2,262	8,350	1,290	2,266	451	50	1,152	1,183	94	1,893	220	90	9,705	3,813	833	3	75	74	147	.271	.365	.457	.822
23	J.D. Martinez	331	1,642	6,152	897	1,741	390	24	1,071	601	40	1,714	26	11	6,854	3,172	745	0	61	54	195	.283	.348	.516	.863
24	Eugenio Suárez E. Suárez	325	1,630	5,820	831	1,434	262	15	949	632	103	1,814	36	20	6,627	2,701	602	9	63	16	130	.246	.328	.464	.792
25	Justin Upton J. Upton	325	1,845	6,721	1,058	1,754	350	38	1,003	785	78	1,971	151	59	7,646	3,155	713	3	59	49	142	.261	.342	.469	.812