| NAME | DATE | L | TM | OPP | DEC | W | L% | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | E. Santana | 9/1/2021 | 1 |  KCR | vs |  CLE | L | 0 | 1.000 | 0 | 9.00 | 1 | 0 | 0 | 0 | 1.0 | 2 | 1 | 2 | 0 | 1 | 0 | 1 | 1 | 5 | 0 |
| 2 | | E. Santana | 5/29/2021 | 1 | KCR | @ |  MIN | L | 0 | 1.000 | 1 | 9.00 | 2 | 0 | 0 | 0 | 3.0 | 4 | 3 | 3 | 1 | 1 | 0 | 0 | 0 | 14 | 0 |
| 3 |  | E. Santana | 4/24/2019 | 1 |  CWS | @ |  BAL | L | 0 | 1.000 | 1 | 7.71 | 1 | 0 | 0 | 0 | 4.2 | 6 | 4 | 4 | 1 | 0 | 0 | 0 | 0 | 20 | 0 |
| 4 | | E. Santana | 4/9/2019 | 1 | CWS | vs |  TBR | L | 0 | 1.000 | 1 | 17.18 | 1 | 0 | 0 | 0 | 3.2 | 7 | 7 | 7 | 3 | 3 | 0 | 0 | 0 | 21 | 0 |
| 5 |  | E. Santana | 8/10/2018 | 1 | MIN | @ |  DET | L | 0 | 1.000 | 1 | 7.50 | 5 | 0 | 0 | 0 | 6.0 | 4 | 5 | 5 | 2 | 2 | 0 | 0 | 0 | 24 | 0 |
| 6 | | E. Santana | 9/18/2017 | 1 | MIN | @ |  NYY | L | 0 | 1.000 | 1 | 3.18 | 3 | 0 | 0 | 0 | 5.2 | 7 | 2 | 2 | 1 | 1 | 0 | 0 | 1 | 26 | 2 |
| 7 | | E. Santana | 7/21/2017 | 1 | MIN | vs | DET | L | 0 | 1.000 | 1 | 13.50 | 3 | 0 | 0 | 0 | 3.1 | 7 | 5 | 5 | 2 | 2 | 0 | 0 | 0 | 18 | 1 |
| 8 | | E. Santana | 7/5/2017 | 1 | MIN | vs |  LAA | L | 0 | 1.000 | 1 | 2.00 | 5 | 1 | 0 | 0 | 9.0 | 7 | 2 | 2 | 1 | 2 | 0 | 0 | 0 | 34 | 0 |
| 9 | | E. Santana | 6/30/2017 | 1 | MIN | @ | KCR | L | 0 | 1.000 | 1 | 8.44 | 5 | 0 | 0 | 0 | 5.1 | 8 | 5 | 7 | 2 | 2 | 0 | 0 | 0 | 26 | 0 |
| 10 | | E. Santana | 6/14/2017 | 1 | MIN | vs |  SEA | L | 0 | 1.000 | 1 | 9.00 | 5 | 0 | 0 | 0 | 5.0 | 9 | 5 | 5 | 2 | 1 | 2 | 0 | 0 | 27 | 1 |
Results may be incomplete. StatMuse has complete game-level data for pitcher losses going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
Guardians 
CIN 
STL 
Phillies 
Mets 
Cubs 
Dodgers 
Padres 
Astros 
MIL 
TOR 
PIT 
WSH 
ATL 
BOS 
SFG 
