largest margin of victory in an mlb game since 2021

Since 2021, the Los Angeles Angels have the highest run differential by a team in a game, with a differential of 24 runs versus the Rockies on June 24, 2023.

Interpreted as:

largest margin of victory in an MLB regular-season game since 2021

	TEAM	DIFF	DATE	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Angels	24	6/24/2023	LAA	@	COL	W 25-1	52	25	28	5	0	5	25	6	1	3	0	0	59	48	10	0	0	0	3	.538	.593	.923	1.516
2	Blue Jays	23	7/22/2022	TOR	@	BOS	W 28-5	57	28	29	5	0	5	28	5	1	9	0	0	63	49	10	0	0	0	0	.509	.556	.860	1.415
3	Reds	22	4/20/2025	CIN	@	BAL	W 24-2	51	24	25	4	1	3	23	11	2	6	1	0	64	40	8	0	0	0	1	.490	.594	.784	1.378
4	Padres	21	5/10/2025	SDP	@	COL	W 21-0	50	21	24	4	1	5	20	5	0	4	0	0	56	45	10	0	1	0	0	.480	.518	.900	1.418
5	Cubs	21	4/23/2022	CHC	vs	PIT	W 21-0	48	21	23	4	0	1	19	4	1	3	2	0	53	30	5	0	0	0	1	.479	.528	.625	1.153
6	Dodgers	21	7/10/2021	LAD	vs	ARI	W 22-1	44	22	21	2	1	8	22	8	1	4	0	0	53	49	11	0	0	0	2	.477	.566	1.114	1.680
7	Blue Jays	19	5/23/2023	TOR	@	TBR	W 20-1	52	20	27	3	1	4	18	1	0	9	2	0	54	44	8	0	1	0	1	.519	.519	.846	1.365
8	Braves	19	5/21/2021	ATL	vs	PIT	W 20-1	41	20	20	7	0	7	20	5	0	9	0	0	49	48	14	1	2	0	0	.488	.521	1.171	1.692
9	Braves	18	8/12/2023	ATL	@	NYM	W 21-3	48	21	22	5	0	6	21	6	1	8	3	0	55	45	11	0	0	0	0	.458	.527	.938	1.465
10	Braves	18	6/30/2021	ATL	vs	NYM	W 20-2	43	20	20	4	0	4	20	6	1	6	1	1	50	36	8	0	0	0	0	.465	.540	.837	1.377
11	Astros	17	7/4/2025	HOU	@	LAD	W 18-1	44	18	20	6	0	5	17	8	1	8	0	1	54	41	11	0	1	1	1	.455	.537	.932	1.469
12	Dodgers	17	5/15/2025	LAD	vs	ATH	W 19-2	40	19	18	2	0	5	19	8	0	6	2	0	50	35	7	0	2	0	0	.450	.520	.875	1.395
13	Diamondbacks	17	7/30/2024	ARI	vs	WSH	W 17-0	45	17	22	6	0	3	17	3	0	3	1	0	49	37	9	0	1	0	0	.489	.510	.822	1.332
14	Red Sox	17	4/27/2024	BOS	vs	CHC	W 17-0	43	17	21	6	0	2	17	2	2	6	1	0	49	33	8	1	1	0	0	.488	.521	.767	1.288
15	Reds	17	9/29/2023	CIN	@	STL	W 19-2	45	19	17	3	2	6	17	2	1	7	1	0	48	42	11	0	0	0	0	.378	.417	.933	1.350
16	Cardinals	17	5/15/2023	STL	vs	MIL	W 18-1	38	18	16	2	0	4	18	8	1	7	0	0	48	30	6	0	1	0	1	.421	.521	.789	1.310
17	Brewers	17	7/1/2022	MIL	@	PIT	W 19-2	44	19	16	5	0	5	18	7	0	2	2	0	51	36	10	0	0	0	0	.364	.451	.818	1.269
18	Athletics	17	8/12/2021	OAK	@	CLE	W 17-0	40	17	14	3	0	2	17	10	3	4	0	0	54	23	5	0	1	0	1	.350	.500	.575	1.075
19	Nationals	17	7/19/2021	WSH	vs	MIA	W 18-1	41	18	18	3	1	6	18	2	1	6	0	0	44	41	10	0	0	0	1	.439	.477	1.000	1.477
20	Dodgers	16	5/31/2025	LAD	vs	NYY	W 18-2	43	18	21	5	0	5	18	7	0	5	0	0	51	41	10	0	1	0	1	.488	.549	.953	1.503
21	Cubs	16	4/12/2025	CHC	@	LAD	W 16-0	47	16	21	5	0	4	16	4	1	4	1	0	53	38	9	0	1	0	0	.447	.491	.809	1.299
22	Dodgers	16	9/19/2024	LAD	@	MIA	W 20-4	39	20	16	3	0	3	19	10	2	6	4	0	53	28	6	0	2	0	0	.410	.528	.718	1.246
23	Athletics	16	5/4/2024	OAK	vs	MIA	W 20-4	45	20	21	1	1	6	20	6	3	3	0	0	54	42	8	0	0	0	1	.467	.556	.933	1.489
24	Diamondbacks	16	4/19/2024	ARI	@	SFG	W 17-1	48	17	22	6	0	1	16	5	0	5	0	0	53	31	7	0	0	0	1	.458	.509	.646	1.155
25	Red Sox	16	8/24/2023	BOS	@	HOU	W 17-1	49	17	25	6	0	3	17	6	2	7	1	0	58	40	9	0	1	0	2	.510	.569	.816	1.385