The Seattle Mariners have an 87-102 record against the Red Sox since 2000.

	OPP	REC	W%	G	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Red Sox	87-102	.460	189	87	102	6,509	823	1,613	318	33	174	784	602	72	1,535	163	41	7,268	2,519	525	36	49	35	129	.248	.316	.387	.703
2	Yankees	78-115	.404	193	78	115	6,501	748	1,554	297	16	176	721	550	73	1,547	108	56	7,213	2,411	489	40	49	37	123	.239	.303	.371	.674
3	Tigers	98-90	.521	188	98	90	6,465	855	1,675	319	35	198	813	599	72	1,374	115	50	7,219	2,658	552	32	51	37	141	.259	.326	.411	.738
4	Blue Jays	94-93	.503	187	94	93	6,502	863	1,711	313	31	212	829	648	73	1,354	128	45	7,311	2,722	556	44	44	47	136	.263	.335	.419	.753
5	White Sox	91-100	.476	191	91	100	6,560	859	1,649	292	23	210	821	641	66	1,399	147	32	7,363	2,617	525	41	55	40	143	.251	.322	.399	.721
6	Royals	110-78	.585	188	110	78	6,502	976	1,779	360	35	218	932	656	70	1,311	106	47	7,330	2,863	613	36	66	37	140	.274	.343	.440	.784
7	Guardians	89-94	.486	183	89	94	6,232	795	1,535	322	27	207	757	587	60	1,381	106	45	6,940	2,532	556	27	34	27	129	.246	.316	.406	.722
8	Twins	103-96	.518	199	103	96	6,875	871	1,812	321	35	222	829	511	56	1,411	104	41	7,545	2,869	578	46	57	23	147	.264	.317	.417	.735
9	Angels	213-237	.473	450	213	237	15,328	1,957	3,905	743	57	469	1,855	1,368	177	3,309	299	122	17,072	6,169	1,269	90	109	94	322	.255	.321	.402	.723
10	Rangers	231-225	.507	456	231	225	15,701	2,139	4,111	796	69	456	2,016	1,492	201	3,274	291	84	17,610	6,413	1,321	82	134	77	338	.262	.331	.408	.740
11	Athletics	245-209	.540	454	245	209	15,321	1,895	3,827	733	51	442	1,812	1,363	158	3,222	255	108	17,041	5,988	1,226	89	110	102	362	.250	.315	.391	.706
12	Rays	101-83	.549	184	101	83	6,215	786	1,524	273	27	187	748	574	56	1,450	107	54	6,927	2,412	487	43	39	33	126	.245	.313	.388	.701
13	Orioles	97-93	.511	190	97	93	6,476	855	1,641	311	26	201	816	611	58	1,287	114	53	7,245	2,607	538	42	58	42	117	.253	.321	.403	.723
14	Padres	66-54	.550	120	66	54	4,079	568	1,059	193	20	141	542	376	42	909	98	25	4,555	1,715	354	26	32	29	72	.260	.326	.420	.747
15	Rockies	25-22	.532	47	25	22	1,578	216	405	61	14	57	204	159	19	338	33	10	1,777	665	132	8	13	10	42	.257	.330	.421	.751
16	Giants	21-18	.538	39	21	18	1,292	152	325	48	4	28	144	162	18	300	40	9	1,496	465	80	11	13	6	36	.252	.340	.360	.700
17	Dodgers	12-23	.343	35	12	23	1,178	132	263	39	2	41	123	102	12	318	21	8	1,309	429	82	10	7	5	11	.223	.290	.364	.654
18	Diamondbacks	23-13	.639	36	23	13	1,245	186	329	64	11	47	177	122	7	288	24	11	1,391	556	122	7	10	9	32	.264	.331	.447	.778
19	Cubs	8-17	.320	25	8	17	867	83	190	42	3	19	77	87	7	225	15	7	971	295	64	6	4	7	15	.219	.294	.340	.635
20	Cardinals	11-13	.458	24	11	13	790	92	188	36	3	25	90	79	5	193	12	6	883	305	64	2	7	3	16	.238	.309	.386	.695
21	Reds	21-6	.778	27	21	6	885	129	219	42	4	46	126	105	18	207	18	9	1,025	407	92	8	9	8	14	.247	.336	.460	.796
22	Astros	92-131	.413	223	92	131	7,472	870	1,707	311	32	231	831	719	94	2,019	131	28	8,329	2,775	574	10	34	16	167	.228	.303	.371	.674
23	Phillies	14-11	.560	25	14	11	850	102	219	39	5	29	97	87	12	223	19	7	967	355	73	8	10	8	17	.258	.332	.418	.749
24	Mets	16-8	.667	24	16	8	813	133	234	40	2	22	123	80	13	206	17	4	921	344	64	7	8	5	20	.288	.358	.423	.781
25	Nationals	12-22	.353	34	12	22	1,138	103	278	38	2	30	100	81	8	257	23	6	1,239	410	70	6	6	7	27	.244	.298	.360	.658