The Philadelphia Phillies have lost the most games by a team, with 11,339 losses.

Interpreted as:

MLB franchise with the most regular-season losses ever

	TEAM	L	W	L%	G	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Phillies	11,339	10,223	.526	21,677	.474	741,712	96,244	193,132	33,385	6,676	14,166	86,470	67,688	5,407	105,207	14,946	2,911	829,731	282,367	54,227	11,914	3,010	3,738	9,852	.260	.326	.381	.706
2	Braves	10,964	11,128	.496	22,246	.504	761,669	99,443	197,833	32,086	6,297	15,040	86,492	67,443	5,060	99,993	14,085	3,062	849,727	287,633	53,423	12,681	2,874	3,651	10,374	.260	.323	.378	.701
3	Pirates	10,838	10,850	.500	21,828	.500	747,717	97,118	196,827	32,331	8,932	12,242	86,628	64,258	5,523	99,447	15,668	3,265	833,291	283,748	53,505	12,557	3,113	3,696	10,038	.263	.325	.379	.704
4	Reds	10,779	10,950	.496	21,868	.504	745,127	98,143	194,159	32,351	7,556	14,305	87,290	66,647	5,500	102,095	18,145	3,401	833,136	284,537	54,212	12,661	3,033	3,645	9,707	.261	.325	.382	.707
5	Cubs	10,779	11,345	.487	22,285	.513	762,629	102,601	199,737	33,726	7,356	15,226	88,191	68,512	5,281	104,915	15,776	3,066	852,350	293,853	56,308	13,026	2,902	3,518	9,952	.262	.326	.385	.711
6	Orioles	10,102	9,131	.525	19,343	.475	657,032	83,531	169,543	29,298	4,909	14,414	77,228	63,240	4,470	98,186	10,538	2,777	738,370	251,901	48,621	10,530	3,098	2,574	10,828	.258	.326	.383	.709
7	Dodgers	10,078	11,451	.468	21,668	.532	738,274	97,784	192,871	31,018	7,000	14,101	88,010	68,827	5,144	100,194	17,325	3,547	828,146	280,192	52,119	12,772	3,053	3,729	9,927	.261	.327	.380	.707
8	Giants	10,029	11,560	.465	21,752	.535	742,393	100,586	195,286	31,323	7,035	15,566	90,061	68,245	5,668	99,419	16,511	3,140	830,977	287,377	53,924	11,662	3,009	4,016	10,168	.263	.329	.387	.716
9	Cardinals	9,987	10,517	.487	20,635	.513	705,860	92,315	187,584	31,799	7,049	12,839	84,382	64,130	5,187	98,016	15,006	3,610	790,282	271,998	51,687	11,971	3,134	3,775	10,124	.266	.330	.385	.715
10	Twins	9,972	9,272	.518	19,353	.482	660,197	85,096	173,145	29,733	6,331	11,995	78,341	62,315	5,152	94,324	12,005	3,075	741,015	251,525	48,059	10,189	3,162	2,661	10,959	.262	.329	.381	.710
11	Athletics	9,874	9,344	.514	19,305	.486	654,338	85,206	168,428	29,167	5,331	14,120	78,511	64,454	4,725	98,877	12,094	3,205	737,296	250,617	48,618	10,681	3,098	2,267	10,602	.257	.327	.383	.710
12	White Sox	9,634	9,601	.501	19,338	.499	654,798	84,008	170,032	28,179	5,550	12,273	77,218	62,039	5,244	91,915	13,608	3,481	737,665	246,130	46,002	12,366	3,218	2,461	10,507	.260	.327	.376	.703
13	Tigers	9,579	9,694	.497	19,366	.503	660,389	88,908	174,469	29,559	6,294	14,552	81,869	65,501	4,437	96,577	11,286	2,935	744,438	260,272	50,405	11,009	3,102	2,446	10,699	.264	.333	.394	.727
14	Guardians	9,382	9,868	.487	19,341	.513	659,232	87,443	174,540	31,121	5,496	13,899	80,813	62,562	4,828	94,453	11,894	3,383	741,434	258,350	50,516	11,460	3,352	2,542	10,517	.265	.331	.392	.723
15	Red Sox	9,277	9,972	.482	19,332	.518	661,636	90,290	176,558	33,091	5,596	14,581	83,728	66,766	4,796	95,407	9,619	2,545	747,127	264,584	53,268	10,592	3,337	2,995	11,540	.267	.337	.400	.737
16	Yankees	8,160	10,796	.430	19,044	.570	649,076	92,540	172,333	28,606	5,491	17,292	85,984	68,518	4,922	94,709	11,639	2,799	735,386	263,797	51,389	9,594	3,276	2,826	10,672	.266	.339	.406	.745
17	Rangers	5,316	4,834	.524	10,156	.476	346,722	45,712	89,452	15,951	1,890	10,177	43,191	32,836	2,692	65,034	5,928	2,843	388,038	139,714	28,018	2,962	2,826	2,250	7,789	.258	.325	.403	.728
18	Mets	5,157	4,837	.516	10,002	.484	338,411	41,271	84,561	15,107	1,814	8,558	38,859	32,336	2,848	64,810	5,869	2,733	380,194	128,970	25,479	3,986	2,613	3,136	7,440	.250	.318	.381	.699
19	Angels	5,130	5,033	.505	10,166	.495	344,930	43,984	88,264	15,256	1,808	9,188	41,387	32,258	2,816	62,545	6,038	3,096	386,306	134,700	26,252	3,535	2,767	2,482	7,864	.256	.322	.391	.713
20	Astros	4,978	5,025	.498	10,008	.502	339,636	42,679	86,571	15,876	2,170	8,404	40,164	32,296	2,892	62,790	7,145	3,129	381,562	131,999	26,450	4,027	2,711	3,144	7,393	.255	.323	.389	.711
21	Padres	4,728	4,144	.533	8,874	.467	299,979	35,952	74,802	13,239	1,756	7,242	33,810	28,560	2,119	59,333	5,994	2,600	336,607	113,279	22,237	3,708	2,241	2,685	6,490	.249	.317	.378	.694
22	Royals	4,638	4,223	.523	8,863	.477	303,142	38,767	79,601	14,881	2,284	6,985	36,585	25,958	2,454	52,007	7,072	2,892	336,583	120,005	24,150	2,364	2,665	1,865	6,769	.263	.323	.396	.719
23	Nationals	4,586	4,278	.517	8,868	.483	299,937	37,149	76,114	14,678	1,788	7,588	34,915	28,202	2,612	57,034	6,528	2,770	336,908	117,132	24,054	3,876	2,281	2,880	6,489	.254	.321	.391	.712
24	Brewers	4,545	4,323	.513	8,872	.487	301,187	39,458	77,145	14,377	1,755	8,692	37,382	28,984	2,705	58,763	5,962	2,726	338,448	121,108	24,824	3,160	2,412	2,157	6,601	.256	.325	.402	.727
25	Mariners	3,962	3,615	.523	7,579	.477	258,530	33,656	66,440	12,392	1,258	7,707	31,970	24,512	2,345	49,569	5,011	2,167	289,402	104,469	21,357	1,944	2,071	1,664	5,664	.257	.325	.404	.729