Between the 1942 and 2011 seasons, the New York Yankees had the most wins by a team, with 6,336 wins.

Interpreted as:

MLB most team regular-season wins from 1942 to 2011

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	6,336	4,700	.574	11,056	378,358	53,209	100,370	16,796	2,516	11,037	50,282	40,406	2,691	56,318	5,644	2,480	428,022	155,309	30,349	3,863	2,704	2,540	8,813	.265	.338	.410	.749
2	Dodgers	6,053	5,004	.547	11,077	376,770	48,690	97,829	15,807	2,516	9,073	45,484	37,612	2,264	59,097	7,522	3,206	425,224	145,887	27,396	6,077	2,501	3,278	8,158	.260	.329	.387	.716
3	Cardinals	5,911	5,131	.535	11,075	379,474	49,285	100,635	17,644	3,089	8,033	46,065	36,364	2,362	56,934	7,348	3,243	425,976	148,556	28,766	5,184	2,592	3,417	8,300	.265	.331	.391	.723
4	Red Sox	5,895	5,152	.534	11,067	380,813	53,396	102,318	19,387	2,452	10,478	50,438	41,225	2,631	58,204	4,198	2,201	431,318	158,043	32,317	3,863	2,786	2,591	9,571	.269	.342	.415	.757
5	Braves	5,731	5,296	.520	11,058	376,682	48,591	97,312	16,507	2,219	10,214	45,690	36,762	2,254	58,964	5,335	2,699	423,594	148,899	28,940	5,495	2,401	3,206	8,562	.258	.326	.395	.721
6	Giants	5,692	5,361	.515	11,072	376,632	48,766	96,555	15,888	2,655	10,216	45,647	37,486	2,573	60,338	5,607	2,798	424,531	148,401	28,759	5,390	2,450	3,616	8,268	.256	.326	.394	.720
7	Reds	5,644	5,399	.511	11,063	377,798	48,832	97,753	17,571	2,390	9,859	45,811	36,525	2,462	62,760	7,162	2,919	424,417	149,681	29,820	5,075	2,557	3,278	7,950	.259	.326	.396	.722
8	White Sox	5,597	5,435	.507	11,062	375,705	48,405	97,512	16,172	2,592	8,799	45,412	37,011	2,949	54,921	6,750	3,083	423,167	145,265	27,563	4,735	2,767	2,247	8,637	.260	.329	.387	.715
9	Indians	5,558	5,469	.504	11,050	377,551	49,521	98,682	16,816	2,242	9,920	46,632	37,440	2,625	58,333	5,670	2,980	424,836	149,742	28,978	4,464	2,756	2,198	8,729	.261	.330	.397	.727
10	Tigers	5,524	5,531	.500	11,085	378,306	49,958	98,094	16,372	2,698	10,453	47,009	38,750	2,448	59,358	4,821	2,583	426,306	151,221	29,523	4,217	2,585	2,146	8,796	.259	.330	.400	.730
11	Orioles	5,475	5,548	.497	11,045	375,686	47,902	96,263	16,730	2,087	9,789	45,097	38,589	2,454	58,624	5,077	2,474	423,652	146,534	28,606	4,298	2,625	2,347	9,049	.256	.327	.390	.717
12	Phillies	5,393	5,651	.488	11,065	376,608	47,061	96,359	16,914	2,903	8,816	44,048	37,302	2,576	62,835	6,029	2,570	423,934	145,527	28,633	4,892	2,556	3,340	8,068	.256	.325	.386	.712
13	Twins	5,328	5,714	.483	11,062	378,209	48,541	99,007	17,138	2,905	8,252	45,482	36,796	2,713	56,840	5,575	2,738	424,389	146,711	28,295	4,031	2,640	2,391	9,224	.262	.330	.388	.717
14	Pirates	5,293	5,735	.480	11,063	378,296	47,024	98,520	17,065	3,226	8,215	44,124	33,996	2,539	60,907	6,002	2,791	422,563	146,682	28,506	5,099	2,633	3,302	8,270	.260	.324	.388	.711
15	Athletics	5,289	5,759	.479	11,070	374,970	47,743	94,856	16,084	2,302	9,125	44,722	38,973	2,583	60,075	6,626	2,901	423,472	142,919	27,511	4,340	2,606	2,033	8,711	.253	.325	.381	.707
16	Cubs	5,210	5,823	.472	11,070	378,350	47,124	97,259	16,643	2,743	9,543	44,194	34,980	2,264	62,240	5,189	2,631	423,124	148,017	28,929	5,094	2,436	3,111	8,206	.257	.322	.391	.713
17	Angels	4,053	4,079	.498	8,135	276,260	35,019	71,200	12,029	1,511	6,830	32,842	26,056	2,027	46,404	4,931	2,691	309,821	106,741	20,370	3,242	2,236	2,113	6,306	.258	.324	.386	.710
18	Astros	3,944	4,027	.495	7,976	270,603	33,232	69,004	12,349	1,906	5,849	31,146	25,775	2,129	46,662	5,971	2,687	304,433	102,712	20,104	3,760	2,166	2,867	5,800	.255	.322	.380	.702
19	Rangers	3,843	4,272	.474	8,121	277,777	36,453	72,209	12,652	1,594	7,783	34,384	26,693	1,885	48,379	4,581	2,367	311,316	111,398	22,029	2,657	2,304	1,972	6,424	.260	.327	.401	.728
20	Mets	3,811	4,149	.479	7,968	269,745	32,493	67,684	11,754	1,531	6,246	30,424	25,848	1,880	48,201	4,919	2,395	303,206	101,238	19,531	3,570	2,163	2,740	5,958	.251	.318	.375	.694
21	Royals	3,281	3,546	.481	6,829	234,072	30,283	62,072	11,491	1,860	5,136	28,515	20,740	1,769	37,016	5,488	2,432	260,716	92,691	18,487	2,030	2,105	1,613	5,282	.265	.327	.396	.723
22	Brewers	3,262	3,571	.477	6,837	232,764	30,443	60,300	11,087	1,436	6,295	28,785	22,286	1,888	41,091	4,363	2,270	261,573	93,144	18,818	2,671	1,964	1,793	5,085	.259	.326	.400	.726
23	Nationals	3,247	3,583	.475	6,834	231,167	28,038	58,566	11,204	1,482	5,361	26,261	21,736	1,861	41,115	5,171	2,350	259,863	88,817	18,047	3,348	1,751	2,453	4,998	.253	.320	.384	.705
24	Padres	3,169	3,671	.463	6,842	231,979	27,532	58,363	10,053	1,425	5,124	25,803	22,210	1,462	42,356	4,672	2,166	260,615	86,638	16,602	3,202	1,762	2,357	5,091	.252	.319	.373	.692
25	Blue Jays	2,755	2,790	.497	5,548	190,719	25,670	50,178	9,937	1,269	5,623	24,279	17,494	1,745	32,855	3,586	1,619	212,828	79,522	16,829	1,244	1,626	1,190	4,310	.263	.328	.417	.745