Tom Cheney has struck out the most hitters in a game, with 21 strikeouts against the Orioles on September 12, 1962.
Interpreted as:
MLB pitchers with the most strikeouts in a regular-season game| NAME | SO | DATE | TM | OPP | DEC | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | T. Cheney | 21 | 9/12/1962 | @ | W | 1 | 0.56 | 1 | 0 | 0 | 16.0 | 10 | 1 | 1 | 0 | 4 | 0 | 0 | 0 | 62 | 1 | ||
| 2 |  | M. Scherzer | 20 | 5/11/2016 | vs | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 6 | 2 | 2 | 2 | 0 | 0 | 0 | 0 | 33 | 0 | ||
| 3 |  | R. Johnson | 20 | 5/8/2001 | vs | 1 | 1.00 | 0 | 0 | 0 | 9.0 | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 29 | 0 | |||
| 4 | | K. Wood | 20 | 5/6/1998 | vs | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 29 | 0 | ||
| 5 |  | R. Clemens | 20 | 9/18/1996 | @ | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 32 | 1 | ||
| 6 | | R. Clemens | 20 | 4/29/1986 | vs | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 30 | 0 | ||
| 7 |  | R. Johnson | 19 | 8/8/1997 | vs | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 5 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 35 | 0 | ||
| 8 | | R. Johnson | 19 | 6/24/1997 | vs | L | 1 | 4.00 | 1 | 0 | 0 | 9.0 | 11 | 4 | 4 | 2 | 0 | 0 | 0 | 0 | 37 | 0 | ||
| 9 | | D. Cone | 19 | 10/6/1991 | @ | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 31 | 0 | ||
| 10 |  | N. Ryan | 19 | 6/8/1977 | vs | 1 | 0.00 | 0 | 0 | 0 | 10.0 | 6 | 0 | 1 | 0 | 5 | 0 | 0 | 1 | 41 | 2 | |||
| 11 | | N. Ryan | 19 | 8/20/1974 | vs | L | 1 | 0.82 | 1 | 0 | 0 | 11.0 | 4 | 1 | 1 | 0 | 5 | 0 | 0 | 0 | 41 | 0 | ||
| 12 | | N. Ryan | 19 | 8/12/1974 | vs | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 7 | 2 | 2 | 0 | 2 | 0 | 0 | 0 | 36 | 1 | ||
| 13 | | N. Ryan | 19 | 6/14/1974 | vs | 1 | 2.08 | 0 | 0 | 0 | 13.0 | 8 | 3 | 3 | 1 | 10 | 0 | 0 | 0 | 58 | 0 | |||
| 14 |  | T. Seaver | 19 | 4/22/1970 | vs | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 2 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 31 | 0 | ||
| 15 |  | S. Carlton | 19 | 9/15/1969 | vs | L | 1 | 4.00 | 1 | 0 | 0 | 9.0 | 9 | 4 | 4 | 2 | 2 | 0 | 0 | 0 | 38 | 1 | ||
| 16 | | L. Tiant | 19 | 7/3/1968 | vs | W | 1 | 0.00 | 1 | 1 | 0 | 10.0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 36 | 0 | ||
| 17 |  | C. Kluber | 18 | 5/13/2015 | vs | W | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 26 | 0 | ||
| 18 | | B. Sheets | 18 | 5/16/2004 | vs | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 31 | 0 | ||
| 19 |  | R. Clemens | 18 | 8/25/1998 | vs | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 30 | 0 | ||
| 20 | | R. Johnson | 18 | 9/27/1992 | @ | 1 | 2.25 | 0 | 0 | 0 | 8.0 | 6 | 2 | 2 | 0 | 4 | 0 | 0 | 0 | 34 | 0 | |||
| 21 | | R. Martinez | 18 | 6/4/1990 | vs | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 31 | 0 | ||
| 22 | | B. Gullickson | 18 | 9/10/1980 | vs | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 4 | 2 | 2 | 0 | 2 | 0 | 0 | 0 | 33 | 1 | ||
| 23 | | R. Guidry | 18 | 6/17/1978 | vs | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 4 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 33 | 0 | ||
| 24 | | N. Ryan | 18 | 9/10/1976 | @ | W | 1 | 2.00 | 1 | 0 | 0 | 9.0 | 3 | 2 | 2 | 0 | 9 | 0 | 0 | 0 | 41 | 0 | ||
| 25 | | D. Wilson | 18 | 7/14/1968 | @ | W | 1 | 1.00 | 1 | 0 | 0 | 9.0 | 5 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 33 | 1 | ||
WSH
BAL
WSH
DET
ARI
CIN
CHC
HOU
BOS
SEA
SEA
CWS
OAK
NYM
PHI
CAL
TOR
BOS
SDP
STL
CLE
MIN
MIL
ATL
TOR
KCR
SEA
TEX
LAD
MON
NYY
CWS
HOUResults may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
More MLB News
Slumping shortstop Dansby Swanson out of Cubs starting lineup against the Giants on Saturday
Twins recall former top prospect Royce Lewis from Triple-A
This Date in Baseball - Joe Torre becomes the 10th manager in MLB history to get 2,000 victories
Roki Sasaki’s 10 strikeouts, a harder splitter and a long-awaited breakthrough for the Dodgers
GarcÃa hits 1st grand slam for his 2nd HR of game in Nationals' 14-1 romp over Diamondbacks
Brewers score 8 late runs, stun Rockies 9-7 in wild 10-inning victory
More Rangers Stats
Team Batting Leaders 
HR
10
Burger
RBI
37
Burger
AVG
.311
Jung
Team Pitching Leaders 
W
5
Eovaldi
K
78
deGrom
ERA
3.48
deGrom
Team Rankings
HR
62
21st
R
252
26th
SO
530
14th
ERA
3.70
6th
Rangers
Astros
Angels
CLE
MLB 2026 Batting Leaders
MLB 2026 Pitching Leaders
MLB Fantasy 2026
MLB 2026 Betting
MLB 2026 Standings
| NL East | W | L | PCT | GB |
|---|---|---|---|---|
43 | 21 | .672 | ||
34 | 29 | .540 | 8.5 | |
32 | 32 | .500 | 11.0 | |
29 | 35 | .453 | 14.0 | |
28 | 35 | .444 | 14.5 | |
| NL Central | W | L | PCT | GB |
38 | 23 | .623 | ||
33 | 28 | .541 | 5.0 | |
34 | 30 | .531 | 5.5 | |
33 | 31 | .516 | 6.5 | |
31 | 31 | .500 | 7.5 | |
| NL West | W | L | PCT | GB |
41 | 23 | .641 | ||
33 | 30 | .524 | 7.5 | |
32 | 30 | .516 | 8.0 | |
26 | 38 | .406 | 15.0 | |
24 | 40 | .375 | 17.0 |
Phillies
Marlins
Brewers
Pirates
Diamondbacks
Padres
Giants
Rockies| AL East | W | L | PCT | GB |
|---|---|---|---|---|
37 | 23 | .617 | ||
37 | 26 | .587 | 1.5 | |
31 | 33 | .484 | 8.0 | |
30 | 34 | .469 | 9.0 | |
27 | 35 | .435 | 11.0 | |
| AL Central | W | L | PCT | GB |
36 | 29 | .554 | ||
33 | 30 | .524 | 2.0 | |
30 | 35 | .462 | 6.0 | |
26 | 38 | .406 | 9.5 | |
25 | 39 | .391 | 10.5 | |
| AL West | W | L | PCT | GB |
33 | 31 | .516 | ||
31 | 32 | .492 | 1.5 | |
30 | 33 | .476 | 2.5 | |
29 | 36 | .446 | 4.5 | |
24 | 40 | .375 | 9.0 |
Rays
Red Sox