Since 1900, the New York Yankees have the most wins by a team, with 10,820 wins.

Interpreted as:

MLB team with most regular-season wins since 1900

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	10,820	8,175	.570	19,083	650,391	92,737	172,658	28,672	5,498	17,350	86,173	68,677	4,935	95,024	11,669	2,807	736,890	264,376	51,520	9,596	3,291	2,840	10,699	.265	.339	.406	.745
2	Giants	10,368	9,073	.533	19,534	664,556	87,399	173,923	28,420	5,652	14,993	80,434	61,971	5,107	96,786	12,571	3,149	745,972	258,626	49,065	11,313	3,025	4,019	10,201	.262	.328	.389	.717
3	Dodgers	10,342	9,099	.532	19,536	664,203	85,163	173,204	28,235	5,724	13,702	78,494	62,338	4,445	97,583	13,411	3,553	746,288	253,993	47,661	12,232	3,070	3,742	9,962	.261	.327	.382	.709
4	Cardinals	10,142	9,297	.522	19,545	667,991	86,964	177,532	30,640	6,412	12,603	79,964	60,758	4,804	95,745	13,494	3,618	748,094	258,805	49,655	11,394	3,147	3,777	10,151	.266	.330	.387	.717
5	Red Sox	9,991	9,299	.518	19,373	663,066	90,483	176,922	33,171	5,601	14,631	83,914	66,894	4,818	95,789	9,647	2,554	748,720	265,188	53,403	10,598	3,344	3,002	11,562	.267	.337	.400	.737
6	Guardians	9,887	9,403	.513	19,381	660,541	87,603	174,842	31,178	5,500	13,939	80,964	62,693	4,844	94,792	11,931	3,392	742,903	258,837	50,617	11,465	3,360	2,549	10,544	.265	.331	.392	.723
7	Cubs	9,815	9,636	.505	19,558	664,993	85,299	172,673	29,667	5,722	14,316	78,376	60,972	4,745	102,039	11,984	3,075	746,040	256,732	49,705	12,415	2,915	3,523	9,973	.260	.325	.386	.711
8	Pirates	9,801	9,635	.504	19,532	667,119	84,885	175,884	29,517	7,432	11,845	78,025	58,298	4,795	96,768	12,670	3,279	745,135	255,800	48,794	11,802	3,121	3,701	10,075	.264	.326	.383	.709
9	Tigers	9,722	9,593	.503	19,408	661,832	89,117	174,840	29,629	6,301	14,603	82,068	65,617	4,455	96,932	11,299	2,939	746,025	260,880	50,533	11,009	3,112	2,450	10,727	.264	.333	.394	.727
10	Reds	9,692	9,766	.498	19,553	664,043	84,352	172,543	29,433	6,017	13,775	77,861	60,171	4,843	99,762	13,980	3,412	744,117	255,335	49,225	12,016	3,044	3,649	9,732	.260	.324	.385	.709
11	White Sox	9,617	9,660	.499	19,380	656,175	84,158	170,351	28,252	5,553	12,303	77,361	62,175	5,251	92,284	13,636	3,489	739,203	246,618	46,108	12,373	3,229	2,463	10,532	.260	.327	.376	.703
12	Braves	9,525	9,884	.491	19,520	663,774	82,523	170,981	28,158	4,853	14,226	76,213	60,253	4,435	97,414	10,522	3,070	743,343	251,523	47,237	11,996	2,885	3,658	10,397	.258	.322	.379	.701
13	Athletics	9,357	9,903	.486	19,347	655,792	85,390	168,799	29,243	5,334	14,169	78,692	64,598	4,740	99,245	12,125	3,208	738,920	251,217	48,746	10,683	3,107	2,272	10,638	.257	.327	.383	.710
14	Twins	9,295	9,989	.482	19,393	661,561	85,272	173,484	29,789	6,335	12,044	78,510	62,432	5,175	94,663	12,024	3,083	742,528	252,075	48,168	10,190	3,170	2,664	10,989	.262	.329	.381	.710
15	Orioles	9,149	10,124	.475	19,383	658,390	83,684	169,886	29,364	4,914	14,457	77,371	63,351	4,484	98,536	10,573	2,785	739,867	252,449	48,735	10,532	3,110	2,577	10,862	.258	.326	.383	.709
16	Phillies	9,115	10,302	.469	19,494	663,483	83,060	171,546	29,911	5,451	13,617	76,531	61,196	4,665	102,425	11,590	2,918	743,611	253,210	48,979	11,248	3,019	3,741	9,873	.259	.324	.382	.706
17	Angels	5,054	5,151	.495	10,208	346,329	44,174	88,595	15,315	1,812	9,248	41,568	32,376	2,837	62,956	6,058	3,106	387,859	135,278	26,375	3,540	2,777	2,485	7,889	.256	.322	.391	.713
18	Astros	5,049	4,995	.503	10,049	341,017	42,856	86,941	15,942	2,174	8,450	40,335	32,405	2,909	63,092	7,167	3,137	383,082	132,581	26,566	4,030	2,721	3,145	7,430	.255	.323	.389	.711
19	Mets	4,861	5,174	.484	10,043	339,783	41,454	84,903	15,169	1,819	8,617	39,039	32,497	2,879	65,136	5,909	2,738	381,774	129,561	25,605	3,989	2,626	3,145	7,481	.250	.318	.381	.700
20	Rangers	4,853	5,338	.476	10,197	348,082	45,873	89,757	15,997	1,893	10,223	43,345	32,962	2,708	65,369	5,965	2,853	389,553	140,209	28,113	2,964	2,837	2,254	7,804	.258	.324	.403	.727
21	Brewers	4,346	4,564	.488	8,914	302,563	39,618	77,456	14,434	1,759	8,729	37,535	29,125	2,720	59,120	6,010	2,738	339,996	121,595	24,922	3,167	2,421	2,160	6,620	.256	.324	.402	.726
22	Nationals	4,295	4,609	.482	8,908	301,267	37,314	76,431	14,751	1,792	7,621	35,072	28,308	2,639	57,336	6,557	2,784	338,383	117,629	24,164	3,880	2,289	2,883	6,518	.254	.321	.390	.711
23	Royals	4,242	4,660	.477	8,904	304,554	38,908	79,976	14,945	2,294	7,018	36,722	26,045	2,466	52,277	7,105	2,903	338,115	120,563	24,257	2,374	2,676	1,870	6,794	.263	.323	.396	.719
24	Padres	4,165	4,748	.467	8,915	301,368	36,133	75,139	13,294	1,764	7,276	33,977	28,689	2,130	59,632	6,020	2,608	338,159	113,789	22,334	3,717	2,255	2,688	6,515	.249	.317	.378	.694
25	Blue Jays	3,799	3,820	.499	7,622	261,136	35,237	67,914	13,571	1,493	8,286	33,425	24,218	2,430	49,101	4,582	1,965	291,423	109,329	23,350	1,507	2,132	1,405	5,946	.260	.326	.419	.745