Since 2000, Alex Rodriguez has smashed the most home runs by a third baseman in a season, with 54 home runs in 2007.

	NAME	HR	SEASON	TM	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Alex Rodriguez A. Rodriguez	54	2007	NYY	158	583	143	183	31	0	156	95	21	120	24	4	708	376	85	0	9	11	15	.314	.422	.645	1.067	155	67.5	.445	175	66.2
2	Eugenio Suárez E. Suárez	49	2025	TOT	159	588	91	134	28	0	118	46	16	196	4	1	657	309	77	0	7	2	11	.228	.298	.526	.824	96	18	.347	124	18.9
3	Eugenio Suárez E. Suárez	49	2019	CIN	159	575	87	156	22	2	103	70	11	189	3	2	662	329	73	0	6	4	12	.271	.358	.572	.930	118	34.8	.381	130	26.6
4	Alex Rodriguez A. Rodriguez	48	2005	NYY	162	605	124	194	29	1	130	91	16	139	21	6	715	369	78	0	3	8	8	.321	.421	.610	1.031	151	65	.436	174	64.2
5	Adrian Beltre A. Beltre	48	2004	LAD	156	598	104	200	32	0	121	53	2	87	7	2	657	376	80	0	4	9	15	.334	.388	.629	1.017	133	51.9	.423	161	52
6	Troy Glaus T. Glaus	47	2000	ANA	159	563	120	160	37	1	102	112	2	163	14	11	678	340	85	0	1	6	14	.284	.404	.604	1.008	138	49	.424	150	46
7	Junior Caminero J. Caminero	45	2025	TBR	154	602	93	159	28	0	110	41	3	125	7	1	653	322	73	0	7	1	31	.264	.311	.535	.846	100	23	.357	134	26.3
8	Miguel Cabrera M. Cabrera	44	2013	DET	148	555	103	193	26	1	137	90	5	94	3	0	652	353	71	0	2	19	19	.348	.442	.636	1.078	144	72.1	.455	193	68.8
9	Miguel Cabrera M. Cabrera	44	2012	DET	161	622	109	205	40	0	139	66	3	98	4	1	697	377	84	0	6	17	28	.330	.393	.606	.999	137	57.3	.417	166	53.7
10	Mark Reynolds M. Reynolds	44	2009	ARI	155	578	98	150	30	1	102	76	5	223	24	9	662	314	75	0	3	3	8	.260	.349	.543	.892	108	28.4	.381	127	22.3
11	Nolan Arenado N. Arenado	42	2015	COL	157	616	97	177	43	4	130	34	4	110	2	5	665	354	89	0	11	13	17	.287	.323	.575	.898	106	30.8	.371	121	16.1
12	Nolan Arenado N. Arenado	41	2019	COL	155	588	102	185	31	2	118	62	4	93	3	2	662	343	74	0	8	11	14	.315	.379	.583	.962	124	41	.392	130	26.1
13	Alex Bregman A. Bregman	41	2019	HOU	156	554	122	164	37	2	112	119	9	83	5	1	690	328	80	0	8	2	9	.296	.423	.592	1.015	146	58.7	.418	167	59.1
14	Joey Gallo J. Gallo	41	2017	TEX	145	449	85	94	18	3	80	75	8	196	7	2	532	241	62	0	0	1	3	.209	.333	.537	.869	84	19.2	.364	119	12.6
15	Nolan Arenado N. Arenado	41	2016	COL	160	618	116	182	35	6	133	68	2	103	2	3	696	352	82	0	8	10	17	.294	.362	.570	.932	121	39	.386	126	22.2
16	Josh Donaldson J. Donaldson	41	2015	TOR	158	620	122	184	41	2	123	73	6	133	6	0	711	352	84	2	10	0	16	.297	.371	.568	.939	128	47.9	.398	154	44.8
17	Troy Glaus T. Glaus	41	2001	ANA	161	588	100	147	38	2	108	107	6	158	10	3	708	312	81	0	7	7	16	.250	.367	.531	.898	118	30.4	.378	133	29.8
18	Phil Nevin P. Nevin	41	2001	SDP	149	546	97	167	31	0	126	71	4	147	4	4	624	321	72	0	3	7	13	.306	.388	.588	.976	120	42.9	.408	154	44.2
19	Tony Batista T. Batista	41	2000	TOR	154	620	96	163	32	2	114	35	6	121	5	4	664	322	75	0	3	1	15	.263	.307	.519	.827	92	4.5	.348	100	-0.2
20	Todd Frazier T. Frazier	40	2016	CWS	158	590	89	133	21	0	98	64	4	163	15	5	666	274	61	1	7	1	11	.225	.302	.464	.767	83	4.2	.326	104	3.5
21	José Ramírez J. Ramírez	39	2024	CLE	158	620	114	173	39	2	118	54	1	82	41	7	681	333	80	0	6	12	9	.279	.335	.537	.872	109	29.7	.364	141	32.2
22	José Ramírez J. Ramírez	39	2018	CLE	157	578	110	156	38	4	105	106	8	80	34	6	698	319	81	0	6	15	2	.270	.387	.552	.939	125	43.7	.391	147	39.4
23	Kris Bryant K. Bryant	39	2016	CHC	155	603	121	176	35	3	102	75	18	154	8	5	699	334	77	0	3	5	3	.292	.385	.554	.939	127	45.1	.396	148	41.4
24	Austin Riley A. Riley	38	2022	ATL	159	615	90	168	39	2	93	57	17	168	2	0	693	325	79	0	4	1	13	.273	.349	.528	.878	116	36.8	.377	143	34.7
25	Rafael Devers R. Devers	38	2021	BOS	156	591	101	165	37	1	113	62	7	143	5	5	664	318	76	0	4	7	13	.279	.352	.538	.890	113	32.2	.373	133	26.5