Chris Sale has struck out the most hitters by an active pitcher in a game, with 17 strikeouts versus the Rockies on May 14, 2019.
Interpreted as:
most pitching strikeouts in a regular-season game by active players| NAME | SO | DATE | TM | OPP | DEC | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | C. Sale | 17 | 5/14/2019 |  BOS | vs |  COL | 1 | 2.57 | 0 | 0 | 0 | 7.0 | 3 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 24 | 0 | |
| 2 |  | S. Strider | 16 | 9/1/2022 |  ATL | vs | COL | W | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27 | 0 |
| 3 |  | G. Cole | 16 | 5/4/2018 |  HOU | @ |  ARI | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 29 | 0 |
| 4 |  | G. Holmes | 15 | 6/15/2025 | ATL | vs | COL | L | 1 | 2.84 | 0 | 0 | 0 | 6.1 | 3 | 2 | 3 | 1 | 2 | 1 | 0 | 0 | 24 | 0 |
| 5 |  | B. Snell | 15 | 7/27/2024 |  SFG | vs | COL | 1 | 0.00 | 0 | 0 | 0 | 6.0 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 22 | 1 | |
| 6 |  | G. Cole | 15 | 9/1/2021 |  NYY | @ |  LAA | W | 1 | 1.29 | 0 | 0 | 0 | 7.0 | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 25 | 0 |
| 7 |  | C. Burnes | 15 | 8/11/2021 |  MIL | @ |  CHC | W | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27 | 0 |
| 8 |  | J. deGrom | 15 | 4/23/2021 |  NYM | vs |  WSH | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 29 | 0 |
| 9 | | G. Cole | 15 | 9/8/2019 | HOU | vs |  SEA | W | 1 | 1.13 | 0 | 0 | 0 | 8.0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 25 | 0 |
| 10 |  | S. Bieber | 15 | 5/19/2019 |  CLE | vs |  BAL | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 31 | 0 |
| 11 | | C. Sale | 15 | 5/11/2018 | BOS | @ |  TOR | 1 | 3.00 | 0 | 0 | 0 | 9.0 | 6 | 3 | 3 | 1 | 0 | 0 | 0 | 0 | 33 | 0 | |
| 12 |  | C. Sale | 15 | 8/16/2015 |  CWS | vs | CHC | W | 1 | 0.00 | 0 | 0 | 0 | 7.0 | 1 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 26 | 0 |
| 13 |  | Y. Darvish | 15 | 8/12/2013 |  TEX | @ | HOU | W | 1 | 1.13 | 0 | 0 | 0 | 8.0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 26 | 0 |
| 14 | | C. Sale | 15 | 5/28/2012 | CWS | @ |  TBR | W | 1 | 1.23 | 0 | 0 | 0 | 7.1 | 3 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 27 | 0 |
| 15 | | G. Kirby | 14 | 9/14/2025 | SEA | vs | LAA | W | 1 | 2.84 | 0 | 0 | 0 | 6.1 | 3 | 2 | 2 | 2 | 0 | 0 | 0 | 0 | 22 | 0 |
| 16 | | G. Kirby | 14 | 6/8/2025 | SEA | @ | LAA | W | 1 | 2.57 | 0 | 0 | 0 | 7.0 | 2 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 23 | 0 |
| 17 | | M. Meyer | 14 | 4/21/2025 |  MIA | vs |  CIN | W | 1 | 0.00 | 0 | 0 | 0 | 6.0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 23 | 0 |
| 18 |  | P. López | 14 | 6/23/2024 |  MIN | @ |  OAK | W | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 27 | 0 |
| 19 |  | L. Gil | 14 | 5/18/2024 | NYY | vs | CWS | W | 1 | 1.50 | 0 | 0 | 0 | 6.0 | 5 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 24 | 0 |
| 20 |  | J. Flaherty | 14 | 4/30/2024 |  DET | vs |  STL | 1 | 0.00 | 0 | 0 | 0 | 6.2 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 23 | 0 | |
| 21 | | T. Glasnow | 14 | 4/9/2024 |  LAD | @ | MIN | W | 1 | 0.00 | 0 | 0 | 0 | 7.0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 24 | 0 |
| 22 |  | H. Greene | 14 | 9/20/2023 | CIN | vs | MIN | 1 | 1.29 | 0 | 0 | 0 | 7.0 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 25 | 0 | |
| 23 | | P. López | 14 | 9/10/2023 | MIN | vs | NYM | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 28 | 0 | |
| 24 | | T. Glasnow | 14 | 9/6/2023 | TBR | vs | BOS | W | 1 | 1.50 | 0 | 0 | 0 | 6.0 | 3 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 22 | 0 |
| 25 | | C. Burnes | 14 | 9/8/2022 | MIL | vs | SFG | W | 1 | 1.13 | 0 | 0 | 0 | 8.0 | 3 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 27 | 0 |
Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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